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A novel synthesis of some 2-imino-4-thiazolidinone derivatives

Matloubi Moghaddam, F ; Sharif University of Technology | 2007

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  1. Type of Document: Article
  2. DOI: 10.1002/jhet.5570440106
  3. Publisher: HeteroCorporation , 2007
  4. Abstract:
  5. (Chemical Equation Presented) An efficient and simple route is presented to the synthesis of some iminothiazolidinone derivatives. α-Chloro amide derivatives undergo coupling reaction with isothiocyanate in the presence of a mild base, followed by nucleophilic substitution of chlorine by the sulfur atom of isothiocyanate
  6. Keywords:
  7. Amide ; Base ; Chloride ; Imine ; Isothiocyanic acid derivative ; Sulfur ; Thiazolidine derivative ; Cross coupling reaction ; Quantum yield ; Reaction analysis ; Stereochemistry ; Substitution reaction ; Synthesis
  8. Source: Journal of Heterocyclic Chemistry ; Volume 44, Issue 1 , 2007 , Pages 35-38 ; 0022152X (ISSN)
  9. URL: https://onlinelibrary.wiley.com/doi/10.1002/jhet.5570440106