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Unified Modeling and Simulation of Cardio-Pulmonary System in Human Body to Mimic Central Nervous System Behavior to Control the Oxygen & CO2 Levels in this System

Hashemi, Mostafa | 2021

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 54305 (06)
  4. University: Sharif University of Technology
  5. Department: Chemical and Petroleum Engineering
  6. Advisor(s): Bozorgmehry Boozarjomehry, Ramin
  7. Abstract:
  8. A mathematical model helps to understand any system with any level of complication, such as the human body. The heart, vascular system, and lungs are three important parts of each body that life is impossible without them. The performance of the cardiovascular and respiratory systems is tuned by a group of complex mechanisms which are called regulatory mechanisms. Therefore, a model which describes the behavior of these mechanisms has great importance. The goal of this research is to provide and simulate the newest and most complete model in this field. The presented model should consist of the heart, vascular system, lungs, respiratory system, gas exchange and transport, and finally regulatory mechanisms. The model is lumped and zero-dimensional with all of the mentioned parts. The performance of the model in basal conditions, hypoxia, and hypercapnia was compared with physiological data. This complete model provides the opportunity to study lots of related topics. It can simulate the behavior of regulatory mechanisms and their effects on the cardiorespiratory system in different situations like doing exercises, sleep, stress, excitement, …. Furthermore, it can help studying cardiovascular-related sickness, prescribing appropriate drugs, and resuscitation scenarios
  9. Keywords:
  10. Cardio Respiratory System ; Central Nervious System ; Baroreceptor ; Chemoreceptor ; Cardiorespiratory System Simulation ; Regulatory Mechanisms

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