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Bioresorbable composite polymeric materials for tissue engineering applications

Hajebi, S ; Sharif University of Technology | 2021

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  1. Type of Document: Article
  2. DOI: 10.1080/00914037.2020.1765365
  3. Publisher: Bellwether Publishing, Ltd , 2021
  4. Abstract:
  5. This review covers the development of bioresorbable polymeric composites for applications in tissue engineering. Various commercially available bioresobable polymers are described, with emphasis on recent bioresorbable composites based on natural and synthetic polymers. Bioresorbable polymers contain hydrolyzable bonds, which are subjected to chemical degradation via either reactive hydrolysis or enzyme-catalyzed active hydrolysis. For synthetic polymers, chemical hydrolysis is the most important mode of degradation. The degradation rate can be controlled by varying the molecular weight and crystallinity. Examples of bioresorbable polymers are: polyurethane, poly(D,L)lactide, poly(lactic-co-glycolic) acid, poly(α-hydroxy acids), cross-linked polyester hydrogels, poly(orthoesters), polyanhydrides and polyethylene glycol. © 2020 Taylor & Francis Group, LLC
  6. Keywords:
  7. Crosslinking ; Crystallinity ; Degradation ; Hydrolysis ; Natural polymers ; Tissue ; Alpha hydroxy acids ; Bioresorbable polymers ; Chemical degradation ; Chemical hydrolysis ; Hydrolyzable bonds ; Poly lactic-co-glycolic acid ; Polymeric composites ; Tissue engineering applications ; Tissue engineering
  8. Source: International Journal of Polymeric Materials and Polymeric Biomaterials ; Volume 70, Issue 13 , 2021 , Pages 926-940 ; 00914037 (ISSN)
  9. URL: https://ieeexplore.ieee.org/document/9406816