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Recent advances in the modification of carbon-based quantum dots for biomedical applications

Alaghmandfard, A ; Sharif University of Technology | 2021

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  1. Type of Document: Article
  2. DOI: 10.1016/j.msec.2020.111756
  3. Publisher: Elsevier Ltd , 2021
  4. Abstract:
  5. Carbon-based quantum dots (CDs) are mainly divided into two sub-groups; carbon quantum dots (CQDs) and graphene quantum dots (GQDs), which exhibit outstanding photoluminescence (PL) properties, low toxicity, superior biocompatibility and facile functionalization. Regarding these features, they have been promising candidates for biomedical science and engineering applications. In this work, we reviewed the efforts made to modify these zero-dimensional nano-materials to obtain the best properties for bio-imaging, drug and gene delivery, cancer therapy, and bio-sensor applications. Five main surface modification techniques with outstanding results are investigated, including doping, surface functionalization, polymer capping, nano-composite and core-shell structures, and the drawbacks and challenges in each of these methods are discussed. © 2020 Elsevier B.V
  6. Keywords:
  7. Biocompatibility ; Carbon ; Carbon Quantum Dots ; Composite structures ; Gene transfer ; Graphene quantum dots ; Medical applications ; Nanocomposites ; Nanocrystals ; Nanosensors ; Biomedical applications ; Biomedical science ; Core shell structure ; Functionalizations ; Photoluminescence properties ; Surface Functionalization ; Surface modification techniques ; Zero-dimensional ; Semiconductor quantum dots ; Polymer ; Quantum dot ; Gene Transfer Techniques ; Graphite ; Polymers ; Quantum Dots
  8. Source: Materials Science and Engineering C ; Volume 120 , 2021 ; 09284931 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S0928493120336754