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Lithium perchlorate-catalyzed three-component coupling: a facile and general method for the synthesis of α-aminophosphonates under solvent-free conditions

Azizi, N ; Sharif University of Technology | 2003

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  1. Type of Document: Article
  2. DOI: 10.1002/ejoc.200300479
  3. Publisher: Wiley-VCH Verlag , 2003
  4. Abstract:
  5. A simple, efficient, and general method has been developed for the synthesis of α-aminophosphonates in the presence of solid lithium perchlorate under solvent-free conditions. Thus secondary and tertiary α-aminophosphonates were synthesized relatively quickly in good yields at room temperature. © Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003
  6. Keywords:
  7. Lewis acids ; Nucleophilic addition ; Phosphonate ; Solvent effects
  8. Source: European Journal of Organic Chemistry ; Issue 23 , 2003 , Pages 4630-4633 ; 1434193X (ISSN)
  9. URL: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.200300479