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A new protocol for the Baylis-Hillman reaction: The reaction of iminium salts prepared in situ with methyl acrylate

Azizi, N ; Sharif University of Technology | 2002

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  1. Type of Document: Article
  2. DOI: 10.1016/S0040-4039(02)00803-1
  3. Publisher: 2002
  4. Abstract:
  5. In situ prepared iminium salts are very effective electrophiles in Baylis-Hillman reactions and react with methyl acrylate in the presence of a catalytic amount of a tertiary amine at ambient temperatures to afford the corresponding Baylis-Hillman adducts. The product undergoes conjugated addition with (trimethylsilyl)dialkylamines to give the diamine 5 in good yields. © 2002 Elsevier Science Ltd. All rights reserved
  6. Keywords:
  7. Baylis-Hillman reaction ; Diamine ; Iminium salt ; Lithium perchlorate
  8. Source: Tetrahedron Letters ; Volume 43, Issue 24 , 2002 , Pages 4305-4308 ; 00404039 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/pii/S0040403902008031?via%3Dihub