Loading...

Iron oxyhydroxide nanoparticles: green synthesis and their cytotoxicity activity against A549 human lung adenocarcinoma cells

Sadeghi, H ; Sharif University of Technology | 2022

144 Viewed
  1. Type of Document: Article
  2. DOI: 10.1007/s12210-022-01065-w
  3. Publisher: Springer Science and Business Media Deutschland GmbH , 2022
  4. Abstract:
  5. Iron oxyhydroxide (α-FeOOH, Goethite) is one of the most thermodynamically stable iron oxides and a widespread soil mineral. In this study, a mixture of two phenolic extracts of rosemary and Echinacea was utilized as stabilizing and reducing agents for the synthesis of Goethite (FeOOH) nanoparticles without utilizing harmful toxic solvents. The resulting nanoparticles were characterized by X-ray powder diffraction (XRD), field emission scanning electron microscopy (FESEM)-energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), vibrating-sample magnetometer (VSM), thermogravimetry/differential thermal analysis (TG/DTA), and Brunauer–Emmett-Teller (BET). MTT assay was applied for evaluating the possible toxicity of the nanoparticles against A549 human lung adenocarcinoma cells. © 2022, The Author(s), under exclusive licence to Accademia Nazionale dei Lincei
  6. Keywords:
  7. Iron oxide ; Iron oxyhydroxide ; Lung adenocarcinoma cells ; Plant ; Field emission microscopes ; High resolution transmission electron microscopy ; Iron oxides ; Nanoparticles ; Reducing agents ; Scanning electron microscopy ; Synthesis (chemical) ; Thermogravimetric analysis ; X ray powder diffraction ; Adenocarcinoma cells ; Green synthesis ; Human lung adenocarcinoma cells ; Iron oxyhydroxides ; Lung adenocarcinoma cell ; Phenolic extracts ; Plant ; Soil minerals ; Thermodynamically stable ; α-FeOOH ; Biological organs
  8. Source: Rendiconti Lincei ; Volume 33, Issue 2 , 2022 , Pages 461-469 ; 20374631 (ISSN)
  9. URL: https://link.springer.com/article/10.1007/s12210-022-01065-w