Detection of Nanometer Size Species using a Nanofluidic Sensor

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Khansari, Ali Asghar | 2020

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Type of Document: M.Sc. Thesis
Language: Farsi
Document No: 56494 (08)
University: Sharif University of Technology
Department: Mechanical Engineering
Advisor(s): Taghipoor, Mojtaba; Nouri Broujerdi, Ali
Abstract:
Detecting small particles is one of the needs of researchers. Industrial and research developments in nano and biotechnology expands the need of suitable equipments. One of the challenges in this field is detecting the qualitative and quantitative properties in the sample. Until today there are numerous methods to detect the properties of the particles and different commercial machines are presented for this purpose. In this method, based on one the methods of detecting particles, called resistive pulse sensing, a mechanism is composed and by its help 7 um and 800 to 2000 nm particles are distinguished separately. This sensor has two important parts: the fluid and the electronic. In the fluid part the sample is transitted through the micropipette by a syringe pump. The most challenging part of this investigation was composing a geometric micropipette. For this purpose, the method of pulling capillary tubes was useful. In the electronic part of the system, the current made by transited particles are perceived and amplified. And ultimately by analyzing the datas, the number of particles is countable
Keywords:
Resistive Pulse Sensing ; Micropipette Aspiration ; Particle Size Detection ; Microfluidic Devices ; Nanometric Particle Size ; Sensing

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