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Design and Simulation of Integrated Bio-Impedance Driver and Sensor Circuits

Ghouchani, Arman | 2024

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 56866 (05)
  4. University: Sharif University of Technology
  5. Department: Electrical Engineering
  6. Advisor(s): Sharifkhani, Mohammad
  7. Abstract:
  8. Cardiovascular diseases stand as leading contributors to human mortality and disability, with heart muscle diseases, particularly acute and chronic failures, prevalent among them. While various diagnostic methods exist, an accurate, non-invasive, portable, easily accessible, and minimally disruptive approach for monitoring, requiring no frequent clinic visits, takes precedence. Early diagnosis and continuous fluid status monitoring through bioimpedance measurements of chest size are crucial in mitigating the mortality associated with these diseases. Utilizing bioimpedance as a non-invasive signal, this system facilitates ongoing vital parameter monitoring, treatment strategy optimization, and patient care. This thesis presents the design of a digital block chain including a direct digital synthesizer, mixed signal blocks including a digital-to-analog converter, and analog blocks consisting of a sample and hold block, a low-pass filter block, a current driver, and a current feedback instrumentation amplifier. These integrated blocks collectively measure chest impedance. The system attains a remarkable resolution of 100 mΩ, coupled with low noise and distortion levels, ensuring precise and dependable measurements. Implemented in 65 nm technology, the circuit operates with a supply voltage of 1.2 V and a power consumption of 720 microwatts. Operating within the frequency range of 10 KHz to 1 MHz, the system captures 16 distinct samples, facilitating the generation of a Cole-Cole diagram for in-depth patient condition analysis
  9. Keywords:
  10. Bioimpedance Meter ; Bioimpedance Spectroscopy ; Chronic Heart Failure Disease ; Digital to Analog Converter ; Low Pass Filters ; Current Driver (CD) ; Current Feedback Instrumentation Amplifier (CFIA) ; Sampler and Holder

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