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Synthesis of the core/shell structure of polycaprolactone@curcumin-gluten for drug delivery applications

Rami, M.R ; Sharif University of Technology | 2023

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  1. Type of Document: Article
  2. DOI: 10.33263/BRIAC131.087
  3. Publisher: AMG Transcend Association , 2023
  4. Abstract:
  5. In this study, polycaprolactone (PCL) nanoparticles were effectively synthesized as novel drug delivery systems by the electrospray method. Curcumin (Cur) was selected as the model drug with further enhanced stability of its composition with gluten (GLU). The physical-chemical characterization, including FTIR, UV-vis, and thermal analysis of PCL@Cur-GLU nanocapsules, are explored. The in vitro release profiles described by Ritger–Peppas models were also investigated, showing sustained release for 15 h after a burst release within the first five hours. © 2022 by the authors
  6. Keywords:
  7. Curcumin ; Drug delivery ; Gluten ; Polycaprolactone
  8. Source: Biointerface Research in Applied Chemistry ; Volume 13, Issue 1 , 2023 ; 20695837 (ISSN)
  9. URL: https://biointerfaceresearch.com/wp-content/uploads/2022/02/BRIAC131.087.pdf