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The effect of TiO2 nanotubes on the biological properties of porous titanium foam by anodization technique for orthopedic application
Haghjoo, R ; Sharif University of Technology | 2023
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- Type of Document: Article
- DOI: 10.22059/jufgnsm.2023.01.10
- Publisher: University of Tehran , 2023
- Abstract:
- In the present study, the TiO2 nanotubes were grown on the surface of porous titanium foam by the anodization method. The surface of titanium foam before and after the coating of TiO2 nanotubes was structurally and morphologically characterized by X-ray diffraction (XRD), field emission electron microscope (FESEM) equipped with energy-dispersive X-ray (EDX). Additionally, the cytocompatibility of TiO2-coated porous titanium foam was evaluated by methyl thiazol tetrazolium (MTT) assay. The results have shown that the anatase crystalline phase was formed on the surface with a uniform thickness of 2.5 μm. Finally, TiO2-coated porous titanium foam was biocompatible and significantly enhanced the proliferation and attachment ofMG-63 osteoblast cells compared to the uncoated substrate. All the results postulated that the coating of titanium substrate with TiO2 nanotube shows excellent promise for orthopedic implant application. © 2023, Journal of Ultrafine Grained and Nanostructured Materials. All Rights Reserved
- Keywords:
- Bone implant ; Cytocompatibility ; Nanotube ; Powder metallurgy ; Titanium foam
- Source: Journal of Ultrafine Grained and Nanostructured Materials ; Volume 56, Issue 1 , 2023 , Pages 99-107 ; 24236845 (ISSN)
- URL: https://jufgnsm.ut.ac.ir/article_92936.html