Sharif Digital Repository

Immediate control of pandemic influenza to avoid casualties and financial losses is an important issue. In this thesis, two types of controllers including optimal controller and adaptive generalized predictive controller based on linear input-output model, with vaccine, treatment and quarantine being controlling variables, have been used to control influenza. Each controlling methods were investigated for different states including single-input single-output and multi-input single-output. Single-input single-output and multi-input single-output models are identified as online and offline using least squares method. Since it is difficult to exactly identify the model parameters, especially at... 

Infectious diseases have always threatened the health of human beings. One of the most important causes of mortality in human societies is infectious diseases. The spread of these diseases in society, even if does not lead to death, can have devastating effects on society. Influenza is one of the infectious diseases that has attracted much attention today. It can be mild or severe and even cause hospitalization and death. Therefore, controlling and preventing the epidemic of this disease is very important. Epidemic models are commonly used to simulate the spread of infectious diseases. In this study to identify the influenza outbreak, a stochastic multigroup SEIR model with the migration...