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    A rewiring mechanism to improve synchronization in Kuramoto networks

    , Article Journal of Statistical Mechanics: Theory and Experiment ; Volume 2022, Issue 11 , 2022 ; 17425468 (ISSN) Hossein Ghorban, S ; Hesaam, B ; Sarbazi Azad, H ; Sharif University of Technology
    Institute of Physics  2022
    Abstract
    The emergence of synchronization among a set of individual oscillators that are coupled in a network is an amazing physical phenomenon that appears in many different systems, from natural sciences to even human behavior. The phenomenon has attracted the attention of many researchers in many fields of science and engineering by the science behind its unique collective behavior without some kind of external organization. One of the most popular models for the dynamical evolution of coupled phase oscillators is the Kuramoto model, which gives a simple yet powerful formalization together with a numerical measure called the degree of synchronization. The crucial role of structural properties of... 

    Developing a multi-objective multi-layer model for optimal design of residential complex energy systems

    , Article International Journal of Electrical Power and Energy Systems ; Volume 138 , 2022 ; 01420615 (ISSN) Davoudi, M ; Jooshaki, M ; Moeini Aghtaie, M ; Hossein Barmayoon, M ; Aien, M ; Sharif University of Technology
    Elsevier Ltd  2022
    Abstract
    Optimal planning of residential complex energy systems requires thorough mathematical modelling to address the interconnections between all the energy installations from the largest ones, shared by all the residents, to the smallest ones in each distinct unit. Besides, conflicting desires of investors and residents in various aspects such as reliability index make this problem more challenging. In response, this paper presents a thorough framework to obtain the optimum design and operation of a residential complex energy system from scratch. To address the appropriate interconnection between various components of such an energy system, a multi-layer energy hub structure is proposed. Besides,... 

    CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells

    , Article BioImpacts ; Volume 12, Issue 4 , 2022 , Pages 337-347 ; 22285652 (ISSN) Azadbakht, M ; Sayadmanesh, A ; Nazer, N ; Ahmadi, A ; Hemmati, S ; Mohammadzade, H ; Ebrahimi, M ; Baharvand, H ; Khalaj, B ; Aghamaali, M. R ; Basiri, M ; Sharif University of Technology
    Tabriz University of Medical Sciences  2022
    Abstract
    Introduction: B lymphocyte-induced maturation protein 1 (BLIMP1) encoded by the positive regulatory domain 1 gene (PRDM1), is a key regulator in T cell differentiation in mouse models. BLIMP1-deficiency results in a lower effector phenotype and a higher memory phenotype. Methods: In this study, we aimed to determine the role of transcription factor BLIMP1 in human T cell differentiation. Specifically, we investigated the role of BLIMP1 in memory differentiation and exhaustion of human T cells. We used CRISPR interference (CRISPRi) to knock-down BLIMP1 and investigated the differential expressions of T cell memory and exhaustion markers in BLIMP1-deficient T cells in comparison with... 

    Main and interaction effects of manufacturing variables on microstructure and fracture of solder-copper connections

    , Article Engineering Failure Analysis ; Volume 139 , 2022 ; 13506307 (ISSN) Mohammadiamiri, M ; Nourani, A ; Hossein Farrahi, G ; Sharif University of Technology
    Elsevier Ltd  2022
    Abstract
    Finding the optimized set of manufacturing parameters to produce strong solder-copper connections requires investigating the main and interaction effects of processing variables on the joint strength and microstructure. In this study, solder joint specimens were prepared at different levels of cooling rate, time above liquidus (TAL), and soldering temperature. Mode I fracture experiments were designed and performed at a strain rate of 0.5 s−1. The fracture load remained constant from the cooling rate of 0.1 to 1.4 °C/s and then decreased by almost 34% with further increase in the cooling rate to 34 °C/s. Increasing TAL from 60 to 120 s reduced the fracture load by almost 27%, while it was... 

    Correction: Know-how-first anti-intellectualism: Williamson against Williamson (Synthese, (2022), 200, 4, (340), 10.1007/s11229-022-03823-7)

    , Article Synthese ; Volume 200, Issue 5 , 2022 ; 00397857 (ISSN) Khalaj, M. H. M. A ; Sharif University of Technology
    Springer Science and Business Media B.V  2022
    Abstract
    The article was originally published with the splitting of the corresponding author name into two author names. The original article has been corrected. © The Author(s), under exclusive licence to Springer Nature B.V. 2022  

    On learning-assisted content-based secure image transmission for delay-aware systems with randomly-distributed eavesdroppers

    , Article IEEE Transactions on Communications ; Volume 70, Issue 2 , 2022 , Pages 1125-1139 ; 00906778 (ISSN) Letafati, M ; Behroozi, H ; Khalaj, B. H ; Jorswieck, E. A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2022
    Abstract
    In this paper, a learning-aided content-based image transmission scheme is proposed, where a multi-antenna source wishes to securely deliver an image to a legitimate destination in the presence of randomly-distributed passive eavesdroppers (Eves). We take into account the fact that not all regions of an image have the same importance from the security perspective. Hence, we employ a hybrid method to realize both the error-free data delivery of public regions - containing less-important pixels; and an artificial noise (AN)-aided transmission scheme for securing the confidential packets. To reinforce system's security, fountain-based packet delivery is also adopted, where the source node... 

    Folic acid-adorned curcumin-loaded iron oxide nanoparticles for cervical cancer

    , Article ACS Applied Bio Materials ; Volume 5, Issue 3 , 2022 , Pages 1305-1318 ; 25766422 (ISSN) Ramezani Farani, M ; Azarian, M ; Heydari Sheikh Hossein, H ; Abdolvahabi, Z ; Mohammadi Abgarmi, Z ; Moradi, A ; Mousavi, S. M ; Ashrafizadeh, M ; Makvandi, P ; Saeb, M. R ; Rabiee, N ; Sharif University of Technology
    American Chemical Society  2022
    Abstract
    Cancer is a deadly disease that has long plagued humans and has become more prevalent in recent years. The common treatment modalities for this disease have always faced many problems and complications, and this has led to the discovery of strategies for cancer diagnosis and treatment. The use of magnetic nanoparticles in the past two decades has had a significant impact on this. One of the objectives of the present study is to introduce the special properties of these nanoparticles and how they are structured to load and transport drugs to tumors. In this study, iron oxide (Fe3O4) nanoparticles with 6 nm sizes were coated with hyperbranched polyglycerol (HPG) and folic acid (FA). The... 

    Hardware-Impaired PHY Secret Key Generation With Man-in-the-Middle Adversaries

    , Article IEEE Wireless Communications Letters ; Volume 11, Issue 4 , 2022 , Pages 856-860 ; 21622337 (ISSN) Letafati, M ; Behroozi, H ; Khalaj, B. H ; Jorswieck, E. A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2022
    Abstract
    In this letter, we examine the PHY layer secret key generation (PHY-SKG) scheme in the presence of man-in-the-middle (MiM) adversary, while legitimate parties suffer from hardware impairments (HIs). Different from previous works on PHY-SKG that consider adversaries who simply try to make an interference in the communication link, the MiM aims to deceive legitimate entities about the source of common randomness. To conquer the MiM attack, legitimate parties utilize randomized pilots (RPs) in our proposed scheme. We analyze the effect of HIs on the performance of system by deriving the achievable secret key rate (SKR). Our results highlight a fundamental limit, as a ceiling phenomena, on the... 

    Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance

    , Article Expert Opinion on Drug Delivery ; Volume 19, Issue 4 , 2022 , Pages 355-382 ; 17425247 (ISSN) Ashrafizadeh, M ; Saebfar, H ; Gholami, M.H ; Hushmandi, K ; Zabolian, A ; Bikarannejad, P ; Hashemi, M ; Daneshi, S ; Mirzaei, S ; Sharifi, E ; Kumar, A.P ; Khan, H ; Heydari Sheikh Hossein, H ; Vosough, M ; Rabiee, N ; Kumar Thakur, V ; Makvandi, P ; Mishra, Y. K ; Tay, F. R ; Wang, Y ; Zarrabi, A ; Orive, G ; Mostafavi, E ; Sharif University of Technology
    Taylor and Francis Ltd  2022
    Abstract
    Introduction: The application of doxorubicin (DOX) in cancer therapy has been limited due to its drug resistance and poor internalization. Graphene oxide (GO) nanostructures have the capacity for DOX delivery while promoting its cytotoxicity in cancer. Areas covered: The favorable characteristics of GO nanocomposites, preparation method, and application in cancer therapy are described. Then, DOX resistance in cancer, GO-mediated photothermal therapy, and DOX delivery for cancer suppression are described. Preparation of stimuli-responsive GO nanocomposites, surface functionalization, hybrid nanoparticles, and theranostic applications are emphasized in DOX chemotherapy. Expert opinion: GO... 

    Energy efficiency through joint routing and function placement in different modes of SDN/NFV networks

    , Article Computer Networks ; Volume 200 , 2021 ; 13891286 (ISSN) Moosavi, R ; Parsaeefard, S ; Maddah Ali, M. A ; Shah-Mansouri, V ; Khalaj, B. H ; Bennis, M ; Sharif University of Technology
    Elsevier B.V  2021
    Abstract
    Network function virtualization (NFV) and software-defined networking (SDN) are two promising technologies to enable 5G and 6G services and achieve cost reduction, network scalability, and deployment flexibility. However, migration to full SDN/NFV networks in order to serve these services is a time-consuming process and costly for mobile operators. This paper focuses on energy efficiency during the transition of mobile core networks (MCN) to full SDN/NFV networks and explores how energy efficiency can be addressed during such migration. We propose a general system model containing a combination of legacy nodes and links, in addition to newly introduced NFV and SDN nodes. We refer to this... 

    On statistical learning of simplices: Unmixing problem revisited

    , Article Annals of Statistics ; Volume 49, Issue 3 , 2021 , Pages 1626-1655 ; 00905364 (ISSN) Najafi, A ; Ilchi, S ; Saberi, A. H ; Motahari, S. A ; Hossein Khalaj, B ; Rabiee, H. R ; Sharif University of Technology
    Institute of Mathematical Statistics  2021
    Abstract
    We study the sample complexity of learning a high-dimensional simplex from a set of points uniformly sampled from its interior. Learning of simplices is a long studied problem in computer science and has applications in computational biology and remote sensing, mostly under the name of “spectral unmixing.” We theoretically show that a sufficient sample complexity for reliable learning of a K-dimensional simplex up to a total-variation error of ε is O(Kε2 log Kε ), which yields a substantial improvement over existing bounds. Based on our new theoretical framework, we also propose a heuristic approach for the inference of simplices. Experimental results on synthetic and real-world datasets... 

    The nano-based theranostics for respiratory complications of COVID-19

    , Article Drug Development and Industrial Pharmacy ; 2021 ; 03639045 (ISSN) Ghasemzad, M ; Hashemian, S. M. R ; Memarnejadian, A ; Akbarzadeh, I ; Hossein Khannazer, N ; Vosough, M ; Sharif University of Technology
    Taylor and Francis Ltd  2021
    Abstract
    High morbidity and mortality caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made coronavirus disease 2019 (COVID-19) the leading challenge for health experts all over the world. Currently, there is no specific treatment for COVID-19; however, thanks to worldwide intense attempts, novel vaccines such as mRNA-1273 (Moderna TX, Inc.) and BNT162b2 (Biontech/Pfizer) were developed very fast and FDA approved them for emergency use. Nanomedicine-based drug delivery can be an advanced therapeutic strategy to deal with clinical complications of COVID-19. Given the fact that SARS-CoV-2 typically affects the respiratory tract, application of inhalable nanoparticles (NPs)... 

    Investigation of the continuum-rarefied flow and isotope separation using a hybrid CFD-DSMC simulation for UF6 in a gas centrifuge

    , Article Annals of Nuclear Energy ; Volume 152 , 2021 ; 03064549 (ISSN) Ghazanfari, V ; Akbar Salehi, A ; Reza Keshtkar, A ; Mahdi Shadman, M ; Hossein Askari, M ; Sharif University of Technology
    Elsevier Ltd  2021
    Abstract
    UF6 gas flow in the total regions of a rotor with the radius of 0.1 m and the length of 1 m in axisymmetric and steady states was simulated using a new hybrid CFD-DSMC method in the OpenFOAM framework. Implicit coupled density-based scheme was performed for CFD method, and Variable Hard Sphere (VHS) and diffuse model were employed in DSMC method. Also, as an initial estimation, the local Knudsen number was applied to determine the interface location between the continuum-rarefied regions (r = 0.0855 m). Then it was modified (r = 0.084 m) to reduce the computational cost. The comparison results of pure CFD and CFD-DSMC methods illustrated that there were large differences between the flow... 

    Linearization error in synchronization of Kuramoto oscillators

    , Article Applied Mathematics and Computation ; Volume 411 , December , 2021 ; 00963003 (ISSN) Hossein Ghorban, S ; Baharifard, F ; Hesaam, B ; Zarei, M ; Sarbazi Azad, H ; Sharif University of Technology
    Elsevier Inc  2021
    Abstract
    Synchronization among a set of networked nodes has attracted much attention in different fields. This paper thoroughly investigates linear formulation of the Kuramoto model, with and without frustration, for an arbitrarily weighted undirected network where all nodes may have different intrinsic frequencies. We develop a mathematical framework to estimate errors of the linear approximation for globally and locally coupled networks. We mathematically prove that the eigenvector corresponding to the largest eigenvalue of the network's Laplacian matrix is enough for examining synchrony alignment and that the functionality of this vector depends on the corresponding eigenvalue. Moreover, we prove... 

    Investigation uncovered the impact of anions on CO2 absorption by low viscous ether functionalized pyridinium ionic liquids

    , Article Journal of Molecular Liquids ; Volume 336 , August , 2021 ; 01677322 (ISSN) Hossein, S ; Dong, H ; Zeng, S ; Umair Ahmad, M ; Khurum Shehzad, F ; Wu, H ; Zhang, Y ; Sharif University of Technology
    Elsevier B. V  2021
    Abstract
    Ionic liquids, which are designable and nonvolatile, have become a hot topic in the field of CO2 separation from industrial gases. In order to utilize the nonvolatile and low heat capacity of ionic liquids, it is necessary to solve the problem of high viscosity of pure ionic liquids. In the present study, ether functionalized pyridinium ion [E1Py]+ with good biodegradability and low viscosity was selected as cation. Ions containing cyano groups were used as anions, such as thiocyanate ion [SCN]-, dicyanamide ion [N(CN)2]-, tricyanomethanide ion [C(CN)3]-. Three ionic liquids with low viscosity were synthesized and characterized by 1HNMR, 13CNMR and FTIR. The physiochemical properties of... 

    Adsorption and oxidation of dye and tetracycline over hydrothermally synthesized polyresorcinol – Ferrite nanoparticles

    , Article Desalination and Water Treatment ; Volume 212 , 2021 , Pages 376-389 ; 19443994 (ISSN) Kaveh, R ; Alijani, H ; Hossein Beyki, M ; Jafari Pirouz, M ; Sharif University of Technology
    Desalination Publications  2021
    Abstract
    This study focuses on developing an efficient material that integrates high adsorption performances of dye and antibiotics as well as effective oxidation activity of it. Herein, we report a facile method to synthesize polyresorcinol@CoFe2 O4 via a one-step hydrothermally route. The prepared composite possesses multifunctional performance for methylene blue (MB) and tetracycline (TC) removal with appropriate magnetic separation operation and significant removal ability with an adsorption capacity of 51.48 and 28.16 mg g–1, respectively. Meanwhile, the aforementioned composite exhibits a high oxidation activity toward MB and TC molecules where the adsorption capacity increases to 1,723 and 120... 

    On learning-assisted content-based secure image transmission for delay-aware systems with randomly-distributed eavesdroppers

    , Article IEEE Transactions on Communications ; 2021 ; 00906778 (ISSN) Letafati, M ; Behroozi, H ; Khalaj, B. H ; Jorswieck, E. A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2021
    Abstract
    In this paper, a learning-aided content-based image transmission scheme is proposed, where a multi-antenna source wishes to securely deliver an image to a legitimate destination in the presence of randomly-distributed passive eavesdroppers (Eves). We take into account the fact that not all regions of an image have the same importance from the security perspective. Hence, we employ a hybrid method to realize both the error-free data delivery of public regions—containing less-important pixels; and an artificial noise (AN)-aided transmission scheme for securing the confidential packets. To reinforce system’s security, fountain-based packet delivery is also adopted, where the source node encodes... 

    Content-Based medical image transmission against randomly-distributed passive eavesdroppers

    , Article 2021 IEEE International Conference on Communications Workshops, ICC Workshops 2021, 14 June 2021 through 23 June 2021 ; 2021 ; 9781728194417 (ISBN) Letafati, M ; Behroozi, H ; Hossein Khalaj, B ; Jorswieck, E. A ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2021
    Abstract
    In this paper, a content-aware medical image transmission scheme is investigated over a multiple-input single-output (MISO) channel in wireless healthcare systems. The multi-antenna-aided access point, as a source node, wishes to wirelessly send medical images of a patient to a trusted destination node, while multiple randomly-located totally passive and non-colluding eavesdroppers (Eves) try to wiretap the transmission. Considering the fact that not all regions of an image have the same importancy level from the security view-point, we first segment the image into two parts: the region of interest (RoI), which more likely contains important diagnostic information regarding the medical image... 

    Performance analysis of heterogeneous cellular caching networks with overlapping small cells

    , Article IEEE Transactions on Vehicular Technology ; 2021 ; 00189545 (ISSN) Rezaei, F ; Hossein Khalaj, B ; Xiao, M ; Skoglund, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2021
    Abstract
    Caching at network edges has attracted more and more research interests recently for the purpose of alleviating the network traffic pressure especially in backhaul links and improving user experience. We study Heterogeneous Cellular Caching Networks (HCCNs) consisting of macro cells in which N small cell base stations (SBSs) equipped with cache memory operate in conjunction with the macro cell base station (MBS). We provide closed-form expressions of the MBS and SBSs utilization factors and average user-experienced-delay in HCCNs with overlapping coverage regions, considering general traffic models for the request arrivals based on the Independent Reference Model (IRM) and renewal traffic... 

    A nine-step approach for developing and implementing an “agricultural drought risk management plan”; case study: Alamut River basin in Qazvin, Iran

    , Article Natural Hazards ; Volume 102, Issue 3 , 2020 , Pages 1187-1205 Fatehi Marj, A ; Hosseini Hossein Abadi, F ; Sharif University of Technology
    Springer  2020
    Abstract
    Occurrence of drought, as an inevitable natural climate feature, cannot be ceased while happening. However, costs of the consequences could be alleviated using mature scientific integrated approaches. To reduce the amount of damage, it is required to provide “Contingency” and “Mitigation” action plans. For this reason, development of efficient operating instructions for various regions based on weather conditions and field studies is needed as well as having a sophisticated understanding of socioeconomic situations. This paper describes an approach to provide the first national agricultural drought risk management plan for a river basin in Iran country as a pilot. The study lasted for...