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metabolomics
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The Pattern Recognition Methods in Combination with Nuclear Magnetic Resonance (NMR)Spectroscopy in Order to Develop a Metabolomic Approach to Breast Cancer Prognosis
, M.Sc. Thesis Sharif University of Technology ; Parastar Shahri, Hadi (Supervisor)
Abstract
The emerging field of “metabolomics” focuses on investigating into the changes of low-molecular-weight – less than 1500 Daltons – molecules, or metabolites, and it has significantly developed in the field of detecting diseases, particularly cancer in recent years. Regarding the importance of breast cancer (BC), especially among women, developing simple, trusted metabolic approaches are crucial. In the present work, utilizing multivariate class-modelling techniques combined to nuclear magnetic resonance (NMR) in order to predict breast cancer based on analyzing the blood serum of healthy and BC patients is presented. To do so, using 42 blood samples, 18 BC patients and 24 healthy individuals,...