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    Simulation of Clogging in Porous Media by Pore Network Model

    , M.Sc. Thesis Sharif University of Technology Razavy, Sina (Author) ; Jamshidi, Saeed (Supervisor) ; Raoof, Amir (Co-Supervisor)
    Abstract
    Clogging of the pores of the porous medium occurs in different processes such as geothermal injection pumps, hydrocarbon wells, and underground water extraction wells. We need a model that can simulate these blockages in order to predict how fundamental variables of the porous medium change under different flow regimes and different particle sizes in the fluid (for example, the relationship between porosity and permeability changes). The aim is to simulate clogging in a porous medium using a pore network model. Simulations should model pore clogging and show how the permeability of the sample changes due to pore clogging. In the pore network, there are often thousands (or millions) of pores... 

    Separation of Plasma from Blood Using a Dielectrophoresis-Assisted Microfluidic Device

    , M.Sc. Thesis Sharif University of Technology Shams, Mehran (Author) ; Mohammadi, Ali Asghar (Supervisor) ; Soltanieh, Mohammad (Supervisor)
    Abstract
    % of human blood makes up of plasma, that this plasma is a rich source of proteins that can be used as biomarkers for a variety of clinical diseases and laboratory research, therefore, it is necessary that the plasma be separate by a high purity percentage. Using a centrifuge It is a common method used to separate plasma from blood, but because it requires large equipment and a large volume of blood, as well as stress caused by centrifugal force, increases the probability of damage to the biomarkers, so it has been tried today that Use methods that are easy to transport and require a small amount of blood. The idea of using the microfluidic device has been put forward for the purpose of... 

    Investigation of the Leading Edge Flap Effects on the Aerodynamic Coefficients of a Cranked Arrow Delta Wing

    , M.Sc. Thesis Sharif University of Technology Karimshahian Bidgoli, Alireza (Author) ; Soltani, Mohammad Reza (Supervisor)
    Abstract
    In this study, investigated the simulation flow over a double-delta wing. The flow field was simulated by three dimension grid and RANS flow equation by K-ω-SST model. In order to investigate effect of AOA and leading edge flap simulated variable AOA and leading edge flap angle. The results shows created two vortex in inside and outside the wing. The vortex burst at high AOA and the Lift decrease after vortex bursting. The using leading edge flap effect on the vortex power and postpone vortex bursting and increasing wing lift coefficient in the high AOA. Also the leading edge flap effect on the pitch moment coefficient and change the pitch moment coefficient curve slope. The other effects of... 

    Design and Fabrication of Water and Oil Separation Membranes Using Nano Technology and Wettability Properties of Surfaces

    , M.Sc. Thesis Sharif University of Technology Heydari, Mohammad Reza (Author) ; Moosavi, Ali (Supervisor)
    Abstract
    Due to population growth, the demand for water supply has increased. This need has drawn attention to the use of consumed and treatable water resources. Organic pollutants are a key source of water pollution. On the other hand, petrochemical oil pollution and frequent oil accidents during oil production or maritime transport have become one of the environmental problems.There are different methods for water and oil separation and water purification that in the present project, selective separation can be achieved by using hydrophobic materials and surface roughness and creating surfaces with two properties: superhydrophobic and ultra-oil friendly. This method is also very effective, cheap... 

    Surface Modification of Ultrafiltration Membranes to Reduce Fouling in the Dairy Industry

    , M.Sc. Thesis Sharif University of Technology Jabari, Behnam (Author) ; Musavi, Abbas (Supervisor) ; Molaei Dehkordi, Asghar (Co-Supervisor)
    Abstract
    In the dairy industry, for the processing of raw milk, including the isolation of living bacteria and microorganisms from milk to increase the shelf life and improve the taste of milk, or the isolation of casein and whey proteins from milk for pHarmaceutical and medical purposes, as well as the production of low-lactose or lactose-free milk for patients with Digestive problems, use membrane processes, especially ultrafiltration and microfiltration, and the main problem in these methods is the fouling of the polymer membranes used, which results in the loss of flux or the reduction of product quality and system efficiency. With the help of bulk modification and surface modification of the... 

    Design & Manufacture of IGF/DGF Plant in Semi Industrial Scale for Wastewater Separation

    , M.Sc. Thesis Sharif University of Technology Hemmati, Amir Hossein (Author) ; Ghotbi, Siroos (Supervisor)
    Abstract
    The increasing demand for energy forced to production of oil as one of the main sources of energy. Along with the increase in oil production, the proportion of water produced with oil is increasing relative to the oil produced. On the other hand, environmental restrictions for the discharge of industrial effluents into the environment are becoming more and more stringent every day. Before discharging the effluent into the environment, petroleum must be removed. The complexity of these issues demonstrates the need to develop new technologies and improve the efficiency of existing technologies. Gas flotation are among the technologies adopted in the field that have been used throughout the... 

    Data Analysis of Gaia and OGLE Projects and Determination Properties of Gravitational Microlensing

    , M.Sc. Thesis Sharif University of Technology Mozaheb, Saeed (Author) ; Rahvar, Sohrab (Supervisor)
    Abstract
    At the beginning of the 20th century, Albert Einstein introduced the equations of general relativity, opening a new avenue for investigating various phenomena. One of the predictions of these equations, gravitational lensing, was observed by Eddington during his lifetime, confirming the theory's ability to describe nature. Gravitational lensing can be categorized into three types: strong lensing, weak lensing, and microlensing. The current focus of research is on observing the separation phenomenon in gravitational microlensing. The observation of gravitational microlensing provides valuable insights into the composition of celestial bodies in the universe. Calculating the mass of different... 

    Design and Simulation of a Passive Microfluidic Device for Particle Separation

    , M.Sc. Thesis Sharif University of Technology Vatankhah, Parham (Author) ; Shamloo, Amir (Supervisor)
    Abstract
    Nowadays, separation and filtration of particles has many industrial applications in biology and medicine. In this thesis, passive microfluidics are designed and simulated which are able to separate and filter particles. Although particles aer generally expected to follow laminar flow streamlines in the absence of external forces, inertial forxes van cause particles to migrate across mictochannels in an accurate and predictable manner. The effect of these forces is invedtigated, and by using previous research, a model is developed to predict these forces. First design is a microchannel with Archimedean spiral which utilizes both inertial forces and Dean flow to separate particles in the... 

    Design, Simulation and Fabrication of Integrated Centrifugal Microfluidic Platform for Separation and Lysis of Circulating Tumor Cells

    , M.Sc. Thesis Sharif University of Technology Momeni, Maede (Author) ; Shamloo, Amir (Supervisor) ; Firoozbakhsh, Keykhosrow (Supervisor)
    Abstract
    Cancer diagnosis area has recently been in the limelight of the medical research and there exist an unremitting focus on the devices & technologies which enable cancer detection in its victims. Lately a genius diagnostic method based on isolation and entrapment of circulating tumor cells has been developed which pave the path for cancer identification. These circulating cells which are detached from the primary tumor are carried out through body by means of circulation system. They play key role in phenomenon called metastasis. Separating these rare cells from multifarious background blood cells, assessing their quantity can supply valuable information on the stage of disease as well as its... 

    Reducing the Size of the Reactor for Production of Fullerene-containing Soot and Study on the Efficiency of Alumina and Silica Gel as Stationary Phase for Separation of C60 and C70

    , M.Sc. Thesis Sharif University of Technology Kadivar Salekoyeh, Mohammad (Author) ; Ghanbari, Bahram (Supervisor) ; Gol Nabi, Hossein (Supervisor)
    Abstract
    In this study, with respect to previous projects, we focused on size reduction of hollow and endohedral fullerenes research reactors. For this reason, we set up two reactors having 1/2 and 3 liters volumes and then such parameters as pressure, reactor temperature, arc duration time, arc time interval and the working electrical current through the electrodes circuit, in both reactors were optimized. The reactors, 3- and 1/2-liter reactors were of types of horizontal and vertical, respectively. In this project spatial angle between two electrodes were also found as effective variable on fullerenes yield in the 3-liters arc reactor for the first time. We found that upon correction of the... 

    Simulation of Droplet Sorting in Microfluidic Systems

    , M.Sc. Thesis Sharif University of Technology Fattahi, Hamid Reza (Author) ; Mousavi, Ali (Supervisor) ; Asghari, Mohsen (Supervisor)
    Abstract
    A new microfluidic device is introduced for sorting the particles based on the hydrodynamic resistance induced in a microchannel which is not needed for additional detection or sorting modules. Hydrodynamic resistance affects physical properties, such as size and deformability of the particle. This device could apply application in cell sorting for remedies, diagnostics, and industrial applications. The device design is performed using an equivalent resistance model, and also numerical simulations are performed. For validation of the results, they are compared with experimental results. Moreover, we will discuss threshold particle size and will introduce a way to approximate it to ... 

    Separating Linkages in 3-Space

    , M.Sc. Thesis Sharif University of Technology Kouhestani, Bahram (Author) ; Mahdavi Amiri, Nezamoddin (Supervisor)
    Abstract
    Here, the properties of separability of linkages are studied. In general, a linkage is a simple polygonal chain embedded in 3-space with disjoint, straight-line edges, which are fixed-length bars. The internal vertices are called joints. If the two end points are connected then the linkage is a closed linkage, otherwise it is an open linkage. By imposing restrictions on the way the bars in joints can move, three kinds of linkages as rigid, revolute and flexible can be introduced. A motion in a linkage is the motion of its vertices that preserves the length of the bars, and adheres the restrictions on joints. A collection of linkages are said to be separatable if for any distance d, there is... 

    Separation of Xylene Isomers

    , M.Sc. Thesis Sharif University of Technology Khademi, Mahmoud (Author) ; Molaei Dehkordi, Asghar (Supervisor)
    Abstract
    Xylene isomers have similar boiling points and, therefore, their separation by conventional distillation is not practical. The industrial separation of these isomers is generally performed by adsorption or crystallization processes, which are very energy consuming. In this work, the various methods of the separation of these isomers have been reviewed and the equilibrium adsorption of these components in liquid phase using two commercial types of zeolite including Z-700 and Na-BETA as adsorbent at 15, 25, and 35 oC and an initial concentration range of up to 50 wt% as well as in single and binary solutions was investigated. It was found that Z-700 adsorbent has no selectivity for the binary... 

    Fabrication of DEP-inertial Microfluidic Device for Focusing and Separation of Particles/Cells

    , M.Sc. Thesis Sharif University of Technology Rezaei, Mohammad Reza (Author) ; Mohammadi, Ali Asghar (Supervisor)
    Abstract
    Separation of particles and cells is one of the most important and practical methods in fields such as biomedicine, medicine and industry. In microfluidics There are various methods for particles and cells separation According to the source of them, they can be categorised as active and passive techniques. Active techniques rely on an external force field. The most important advantage of this method is controlling the force on the particles during the experiment. However, the flow speed is always limited because particles must be exposed to the outer force field for sufficient duration to achieve effective functionality. passive techniques depend entirely on the channel geometry or intrinsic... 

    Separation and Preconcentration of Gold and Silver Nanoparticles Using Cloud Point Extraction

    , M.Sc. Thesis Sharif University of Technology Zare-moghadam, Mousa (Author) ; Hormozi-Nezhad, M.R (Supervisor)
    Abstract
    Separation and identification of metal nanoparticles in surface water samples such as river water is very important. Nanoparticles specially metal nanoparticles have small dimensions can easily pass through from the body's outer immune system and disrupt biological function. Most of the nanoparticles have active surface so environmental contaminants can be absorbed on their surface and then can penerated in the body, and they may cause disease. Therefore determination of nanoparticles type and concentrations and their separation from the surrounding environment, especially surface waters is important. Separation and preconcentration of metal nanoparticles was done by using cloud point... 

    Simulation, Evaluation and Fabrication of a Two-step Microfluidic System to Separate Circulating Tumor Cells

    , M.Sc. Thesis Sharif University of Technology Mir Mohammad Sadeghi, Fatemeh Sadat (Author) ; Vosoughi, Manouchehr (Supervisor) ; Alamzadeh, Iran (Supervisor)
    Abstract
    Cancer is an abnormal growth of cells which is one of the major cause of worldwide’s mortality. Circulating Tumor Cells (CTCs) are rare cancer cells released from the primary or metastatic tumors and transported though the peripheral circulatory system and spreads in body and seize healthy organs. Early detection of CTCs can help in overtaking the cancer, hence isolation of CTCs is an essential step for many therapeutics. In spite of its clinical potential, the isolation and detection of CTCs has been a challenging task due to its rare presence amongst other blood cells (as low as 1–10 CTCs per billions of blood cells), similarity to white blood cell in size and also variability in terms of... 

    Comparative Evaluation of Geometric Shapes for Aircrafts Standard Separation in Air Traffic Management

    , M.Sc. Thesis Sharif University of Technology Aliverdypour, Mohsen (Author) ; Malaek, Mohammad Bagher (Supervisor)
    Abstract
    In today's complex engineering systems, any increase in efficiency naturally comes with concerns about accepted level of safety. As demand for aerial transportation is increasing, more researches are conducted to increase the capacity of current controlled airspaces; as the limited capacity of the so called "en-route" corridors appears to be the main concern in the industry. Meanwhile, a solution is expected to be in more efficient exploitation of the current airspace capacities via optimizing the standards related to maintaining Separation Minima (SM) among flying aircrafts. Current standards assume an aircraft to be at the center of a circle with a radius equal to 5 nm. In this work,... 

    Design, Simulation and Construction of a Microfluidic Device for the Purpose of Target Cells Separation and DNA Extraction

    , M.Sc. Thesis Sharif University of Technology Amani, Ali (Author) ; Shamloo, Amir (Supervisor) ; Nouri Borujerdi, Ali (Supervisor)
    Abstract
    Today, microfluidic experiments have found wide applications in medical sciences, engineering, and chemistry. Because of their small size, microfluidic devices help us to be able to use very little amount of sample for the experiments and also easily control and observe the under-experiment fluid. One of the most important applications of these devices is the separation of cancer cells in blood for counting their number and DNA genetic studies. In the current project we have tried to do the separation of cancer cells from other cells by designing an inertia microchannel. For this purpose, in the first step a geometry for the channel is designed with analyzing the induced forces on the cells.... 

    Using Supported Ionic Liquid Membranes (SILMs) for Selective Separation of CO2/CH4

    , M.Sc. Thesis Sharif University of Technology M.Barghi, Hamed (Author) ; Rashtchian ,Davood (Supervisor) ; Adibi, Mina (Supervisor)
    Abstract
    Supported Ionic Liquid Membranes (SILMs) are fabricated by saturating the pores of a porous support with ionic liquids. To assess the performance of SILMS, it is necessary to obtain data about the properties of ionic liquids such as diffusivity, solubility, and etc. To accomplish this task, in this project the permeability and diffusivity of CO2 and CH4 through three immidazolium-based ionic liquids: [bmim][PF6], [hmim][Tf2N], and "1-methyl-3-(3- tri methoxi silil propyl) imidazolium bis (tri fluoro methyl solphonyl)" , in the temperature range between 27-45 ℃ and pressures within 10-50 kPa, are measured. It is shown in data validation section that the results of this study are in good... 

    Leaching, Solvent Extraction and Separation of Cerium, Lanthanum, Neodymium Rare Earth Elements from Apatite Concentrate of Chadormalu Mine

    , Ph.D. Dissertation Sharif University of Technology Ferdowsi, Ali (Author) ; Youzbashizadeh, Hossein (Supervisor)
    Abstract
    Waste of iron ore concentrate production plant of Chadormalu contains apatite mineral. The content of rare earths elements (REEs) in apatite concentrate of Chadormalu is about one percent. However, considering apatite deposite and production rate, extraction of REEs from apatite is one of valuable source for production of REEs. Lanthanum, cerium and neodymium which have most application amonge other REEs and have the highest frequency in the apatite. Due to their similar physical and chemical properties, it is difficult to separate individual rare earths from each other and the separation process are too complicated. In this study, in order to extract REEs from apatite, it was leached by...