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    Multirate Transfer Functions in Dual Porosity-Dual Permeability Models in Simulation of Naturally Fractured Reservoirs in 2D Two Phase Water-Oil System

    , M.Sc. Thesis Sharif University of Technology Rezaei, Sajjad (Author) ; Taghi Zade Manzari, Meherdad (Supervisor) ; Afshin, Hossein (Co-Advisor) ; Kazemzadeh Hannani, Siamak (Co-Advisor)
    Abstract
    Naturally Fractured Reservoirs (NFRs) play an important role in petroleum industry and the global economy.. The reservoirs of the most complex geological structures in petroleum engineering science, on the other hand the largest sources of hydrocarbons are considered throughout the world and especially in our country. Therefore, characterization and modeling them frst step to develop best practices for hydraulic fracturing gap, optimal design of production Method and evaluate potential reservoirs. Physics of the present work is 2D two-phase immiscible flow under gravittational effect through fractured porous media and the most practical formulas for transfer function in dual porosity-dual... 

    Model Predictive Control for Fast Descending Maneuver of Quadrotor

    , M.Sc. Thesis Sharif University of Technology Nazeri Astanjin, Ahmad (Author) ; Fallah Rajabzadeh, Famida (Supervisor) ; Zohoor, Hassan (Supervisor) ; Nejat Pishkenari, Hossein (Co-Supervisor)
    Abstract
    Quadrotors have limitation in performing fast descending maneuver due to entering a dangerous region in velocity space called Vortex Ring State(VRS) which cause considerable loss of lift that may lead to fall. The purpose of this project is to reduce time of fast descending maneuver without entering VRS region by using model predictive control. First, appropriate nonlinear dynamic model of quadrotor obtained by considering important aerodynamics effect. Then by considering velocity constraints in order to avoid entering the VRS region, a nonlinear model predictive controller(NMPC) has designed. This controller successfully reduce the time of the maneuver up to than ordinary descending.... 

    Introducing of Novel Method to Improve the Process of Imaging in a Gamma Camera Equipped with Square PMTs

    , M.Sc. Thesis Sharif University of Technology Amir Mozafari Sabet, Kiarash (Author) ; Bagheri Shouraki, Saeed (Supervisor) ; Fatemizadeh, Emad (Supervisor) ; Ay, Mohammad Reza (Co-Supervisor)
    Abstract
    The gamma cameras, based on scintillation crystal followed by an array of photomultiplier tubes (PMTs), play a crucial role in nuclear medicine. The use of square PMTs provides the minimum dead zones in the camera. The camera with squared PMTs also reduces the number of PMTs relative to the detection area.In this thesis, we introduced a new read-out method whereby the total cost of the read-out board will be decreased by a factor of 2.4; in return, the energy and spatial resolution of the system will be reduced by 0.3% and 0.4% respectively. We also implemented a positioning module in the FPGA chip via that the transmission rate between FPGA and the computer will be tripled, and the... 

    Experimental Investigation of Heavy Oil Recovery by Liquid CO2 Huff and Puff Method

    , M.Sc. Thesis Sharif University of Technology Ekhlasjoo, Iman (Author) ; Vossoughi, Manoochehr (Supervisor) ; Shadizadeh, Reza (Supervisor) ; Kharrat, Reeaz (Supervisor) ; Ghazanfari, Mohammad Hossein (Co-Advisor)
    Abstract
    In recent years, carbon dioxide is used for enhanced oil recovery of heavy oil. Steam Huff and Puff is one of the enhanced oil recovery methods used for heavy oil. In this study liquid CO2 was used as an injecting fluid instead of steam. In this paper a series of experiments were performed to demonstrate the effect of carbon dioxide injection pressure on huff and puff process. The experimental data are used in lab scale model simulated with commercial simulator Eclipse 300 to investigate the effect of soaking time, injection pore volume and rate of injection on the heavy oil recovery. Result of experiments showed that huff and puff process under miscible pressure condition gives the most... 

    Colloidal gold nanoparticles: an unexpected catalytic activity in aqueous phase with dioxygen

    , Article catalysis letters ; Volume 144, Issue 7 , July , 2014 , pp. 1219-1222 ; 1572-879X Salari, H. (Hadi) ; Robatjazi, H. (Hossein) ; Hormozi-Nezhad, M. (Mohammad Reza) ; Padervand, M. (Mohsen) ; Gholami, M. R. (Mohammad Reza) ; Sharif University of Technology
    2014
    Abstract
    Selective oxidations of alkenes were investigated using molecular oxygen in aqueous solution under mild conditions. Colloidal gold nanoparticles are particularly versatile catalysts for oxidation reaction with exceptionally high efficiency and significant selectivity. Gold nanorods (Au NRs) exhibited a slightly enhanced activity compare to gold nanospheres  

    Modified carrageenan. 1. H-carragPAM, a novel biopolymer-based superabsorbent hydrogel [electronic resource]

    , Article Journal of Bioactive and Compatible Polymers ; September 2005 Vol. 20 no. 5 475-490 Hosseinzadeh, H. (Hossein) ; Pourjavadi, A ; Mahdavinia, G. R ; Zohuriaan-Mehr, , M. J
    Abstract
    A novel kappa-carrageenan (C)-based superabsorbing hydrogel was synthesized through graft copolymerization of acrylamide (AAm) onto a C substrate in the presence of a crosslinking agent. The crosslinked C-poly(AAm) polymer graft was partially hydrolyzed in alkaline medium to yield a superabsorbent resin, H-carragPAM. The resin structure was confirmed using FTIR spectroscopy. The variables of graft copolymerization (monomer, initiator, polysaccharide and crosslinker concentration, reaction temperature and time as well as stirrer speed) that affected on the ultimate water-swelling capacity were optimized. The time-temperature variation of the copolymerization was investigated in terms of the... 

    Experimental Investigation of New Polymers for Enhanced Oil Recovery from one of the Iranian Oil Reservoirs

    , M.Sc. Thesis Sharif University of Technology Torkaman, Mohammad (Author) ; Ramazani Saadatabadi, Ahmad (Supervisor) ; Masihi, Mohsen (Supervisor) ; Ghazanfari, Mohammad Hossein (Supervisor) ; Rasaei, Mohammad Reza (Co-Advisor)
    Abstract
    Polymer flooding is a famous enhanced oil recovery method and is used to reduce mobility ratio of displacing fluid to displaced fluid by forming a stable front in displacing process. Due to high costs, polymer flooding faces economical risks and from this point of view, performance investigation of polymer flooding in laboratory scale was concerned. In this project, performance of 7 types of polymers which have different rheological properties were investigated in fractured/non-fractured carbonated and sandstone reservoirs. These polymers consists of 4 commercial polymers, one branched polymer, one synthetic polymer and one polymer composite which have different molecular weight,... 

    Investigation of Interface Phenomena in Low Salinity/Smart Waterflooding by Applying Molecular Dynamics Simulation

    , Ph.D. Dissertation Sharif University of Technology Badizad, Mohammad Hassan (Author) ; Ayatollahi, Shahab (Supervisor) ; Ghazanfari, Mohammad Hossein (Supervisor) ; Koleini, Mhammad Mehdi (Co-Supervisor)
    Abstract
    Low salinity/smart waterflooding is simple to apply and a promising enhanced oil recovery method in which ion-tuned saltwater is injected into subsurface oil reservoirs. Many aspects of this operation, in particular those pertaining to nano-scale, are not yet fully understood. The present dissertation is an attempt to shed light on the microscopic properties and behavior of rock/brine/oil interfaces throughout low salinity/smart waterflooding. Several simulations were carried out for oil/brine and calcite/brine categories each containing various ions and hydrocarbons compounds. The surface contribution of non-functional oil compounds (aromatics and aliphatics) near brine medium was... 

    Investigation the Effect of additives on Effective Parameters in Design and Production of Agricultural Sulfur Formulation

    , M.Sc. Thesis Sharif University of Technology Abedini, Hassan (Author) ; Safekordi, Ali Akbar (Supervisor) ; Ahmadi, Amir Naser (Supervisor) ; Pakseresht, Saed (Co-Advisor) ; Roozbehani, Ahmad (Co-Advisor)
    Abstract
    Nowadays, different processes are designed in order to convert raw materials to value added products. One of these is the Bentonite sulfur production process. The most important equipment in this process are stirred tanks where mixing operation of molten sulfur with some additives such as functionalized Bentonite and oxides of iron, zinc and manganese are performed.
    In this thesis, following the design and making of a laboratory scale glass baffled stirred tank, the viscosity of molten sulfur and additive suspension has been measured at different temperature (125, 130 and 135oC) and several formulations. Concentration profile of Bentonite has also been obtained by means of local sampling... 

    Fabrication of Bioactive Bone Cement

    , M.Sc. Thesis Sharif University of Technology Mansoori Kermani, Amir Reza (Author) ; Bahrevari, Mohammad Reza (Supervisor) ; Mashayekhan, Shohreh (Supervisor) ; Abd Khodaei, Mohammad Jafar (Supervisor)
    Abstract
    PMMA bone cement lacks biodegradability and the ability to bond with surrounding bone tissue. Therefore, the development of a new generation of bioactive bone cements that are biodegradable and possess adequate mechanical properties as well as desirable setting time is receiving remarkable interest.In this study, we have developed novel mineral-based bioactive bone cements. Our mineral bioactive bone cements were composed of Calcium Sulfate Hemihydrate, Bioactive Glass, and Tricalcium Silicate. Firstly, a binary system composed of Calcium Sulfate Hemihydrate and Bioactive Glass was optimized based on mechanical and setting behavior. Secondly, Tricalcium Silicate was added to the powder phase... 

    Immobilization of modular peptides on graphene cocktail for differentiation of human mesenchymal stem cells to hepatic-like cells

    , Article Frontiers in Chemistry ; Volume 10 , 2022 ; 22962646 (ISSN) Adibi-Motlagh, B ; Hashemi, E ; Akhavan, O ; Khezri, J ; Rezaei, A ; Zamani Amir Zakria, J ; Siadat, S. D ; Sahebghadam Lotfi, A ; Farmany, A ; Sharif University of Technology
    Frontiers Media S.A  2022
    Abstract
    In this study, two novel biomimetic modular peptide motifs based on the alpha-2 subunit of type IV collagen (CO4A2) were designed and immobilized on a graphene platform to imitate integrin and heparan sulfate- (HS-) binding proteins. The in silico study was used to design 9-mer K[KGDRGD]AG and 10-mer KK[SGDRGD]AG for testing designed Integrin-Binding Peptide (dIBP) and HS-Binding Peptide (dHBP). The virtual docking technique was used to optimize the peptide motifs and their relevant receptors. Molecular dynamic (MD) simulation was used to evaluate the stability of peptide-receptor complexes. The effect of the platform on the differentiation of human mesenchymal stem cells (hMSCs) to... 

    Investigation of Ionic Diffusion and Mixing Phenomena in Polymer-Enhanced Low-Salinity Waterflooding Using Molecular Dynamics Simulation

    , M.Sc. Thesis Sharif University of Technology Abdolmaleki, Amir Hossein (Author) ; Ayatollahi, Shahaboddin (Supervisor) ; Mahani, Hassan (Supervisor) ; Esmaeilbeig, Mohammad Amin (Co-Supervisor) ; Pourkhiabani, Nahid (Co-Supervisor)
    Abstract
    Various studies have confirmed that water salinity and its composition significantly affect the efficiency of the waterflooding process. Field-scale operation of low-salinity water injection has been proven to be a cost-effective enhanced oil recovery (EOR) method which is also compatible with the environmental regulations. Although this method has satisfactory results, it faces some challenges, such as in-situ mixing of the injection low-salinity water with the saline water in the host reservoir. The salinity of the injected water increases, as it contacts the high-salinity reservoir brine in the pores. This phenomenon significantly impairs the efficiency of this technique, and increases... 

    Modeling and Laboratory Evaluation of Rheological Properties of Water based Mud for Horizontal Extended Reach Well

    , M.Sc. Thesis Sharif University of Technology Latifi Shirdar, Babak (Author) ; Taghikhani, Vahid (Supervisor) ; Ghazanfari, Mohammad Hossein (Supervisor) ; Tahmasbi Nowtarki, Koroush (Co-Supervisor) ; Kalhor, Mojtaba (Co-Supervisor)
    Abstract
    One of the most important challenges in drilling horizontal and directional wells is the optimization of hydraulics and hole cleaning and ECD management. In these wells, poor hole cleaning can lead to formation of cutting bed on the low side of the annulus and cause problems such as stuck pipe or increase in torque and drag. Also poor hydraulic design can lead to decrease in rate of penetration and thus, increase in costs. Mud weight should be placed inside the range of mud window (more than pore pressure and less than formation fracture pressure) in order to prevent kick of reservoir fluid or mud loss.In this thesis, the main goal is to optimize hydraulics and hole cleaning and manage ECD... 

    The lake urmia environmental disaster in Iran: a look at aerosol pollution

    , Article Science of the Total Environment ; Volume 633 , 2018 , Pages 42-49 ; 00489697 (ISSN) Hossein Mardi, A ; Khaghani, A ; MacDonald, A. B ; Nguyen, P ; Karimi, N ; Heidary, P ; Karimi, N ; Saemian, P ; Sehatkashani, S ; Tajrishy, M ; Sorooshian, A ; Sharif University of Technology
    2018
    Abstract
    Lake Urmia (LU) once was the second largest hypersaline lake in the world, covering up to 6000 km2, but has undergone catastrophic desiccation in recent years resulting in loss of 90% of its area and extensive coverage by playas and marshlands that represent a source of salt and dust. This study examines daily Aerosol Optical Depth (AOD) data from the Moderate Resolution Imaging Spectroradiometer (MODIS) between 2001 and 2015 over northwestern Iran, which encompasses LU. Intriguingly, salt emissions from the LU surface associated with ongoing desiccation do not drive the study region's AOD profile, whereas pollution transported from other regions and emissions around LU are more important.... 

    Folic acid-adorned curcumin-loaded iron oxide nanoparticles for cervical cancer

    , Article ACS Applied Bio Materials ; Volume 5, Issue 3 , 2022 , Pages 1305-1318 ; 25766422 (ISSN) Ramezani Farani, M ; Azarian, M ; Heydari Sheikh Hossein, H ; Abdolvahabi, Z ; Mohammadi Abgarmi, Z ; Moradi, A ; Mousavi, S. M ; Ashrafizadeh, M ; Makvandi, P ; Saeb, M. R ; Rabiee, N ; Sharif University of Technology
    American Chemical Society  2022
    Abstract
    Cancer is a deadly disease that has long plagued humans and has become more prevalent in recent years. The common treatment modalities for this disease have always faced many problems and complications, and this has led to the discovery of strategies for cancer diagnosis and treatment. The use of magnetic nanoparticles in the past two decades has had a significant impact on this. One of the objectives of the present study is to introduce the special properties of these nanoparticles and how they are structured to load and transport drugs to tumors. In this study, iron oxide (Fe3O4) nanoparticles with 6 nm sizes were coated with hyperbranched polyglycerol (HPG) and folic acid (FA). The... 

    Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: stimuli-responsive carriers, co-delivery and suppressing resistance

    , Article Expert Opinion on Drug Delivery ; Volume 19, Issue 4 , 2022 , Pages 355-382 ; 17425247 (ISSN) Ashrafizadeh, M ; Saebfar, H ; Gholami, M.H ; Hushmandi, K ; Zabolian, A ; Bikarannejad, P ; Hashemi, M ; Daneshi, S ; Mirzaei, S ; Sharifi, E ; Kumar, A.P ; Khan, H ; Heydari Sheikh Hossein, H ; Vosough, M ; Rabiee, N ; Kumar Thakur, V ; Makvandi, P ; Mishra, Y. K ; Tay, F. R ; Wang, Y ; Zarrabi, A ; Orive, G ; Mostafavi, E ; Sharif University of Technology
    Taylor and Francis Ltd  2022
    Abstract
    Introduction: The application of doxorubicin (DOX) in cancer therapy has been limited due to its drug resistance and poor internalization. Graphene oxide (GO) nanostructures have the capacity for DOX delivery while promoting its cytotoxicity in cancer. Areas covered: The favorable characteristics of GO nanocomposites, preparation method, and application in cancer therapy are described. Then, DOX resistance in cancer, GO-mediated photothermal therapy, and DOX delivery for cancer suppression are described. Preparation of stimuli-responsive GO nanocomposites, surface functionalization, hybrid nanoparticles, and theranostic applications are emphasized in DOX chemotherapy. Expert opinion: GO...