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    An Approach for Cancer Diagnosis Based on Graph Modeling

    , M.Sc. Thesis Sharif University of Technology Taghizadeh, Ghasem (Author) ; Habibi, Jafar (Supervisor)
    Abstract
    Digital image analysis of histological datasets is a currently expanding field of research. Histological images are inherently complex in nature and contain a wide variety of visual information. Graph-based methods have recently gained immense popularity, as these methods can effectively describe tissue architecture and provide adequate numeric information for subsequent computer-based analysis. Graphs have the ability to represent spatial arrangements and neighborhood relationships of different tissue components, which are essential characteristics observed visually by pathologists during the investigation of specimens. In this thesis, we proposed an automatic approach for classification... 

    Second-Order Homogenization of BCC Lattice Structures to Strain-Gradient Continuum with the Aid of Machine Learning

    , M.Sc. Thesis Sharif University of Technology Taghizadeh, Sina (Author) ; Asghari, Mohsen (Supervisor)
    Abstract
    Engineering of properties was previously not possible. With the advent of additive manufacturing, it became possible to produce structures with architected microstructures, known as lattice structures. The popularity of these structures, due to their lightweight and tunable properties, has increased the importance of their optimal mechanical analysis. Since direct analysis of these structures is computationally prohibitive due to their high level of detail, homogenization methods have been proposed as an alternative. Since these methods couldn't capture size effects, higher-order homogenization methods were introduced. However, despite their good accuracy, these methods are still rarely used... 

    Effects of cognitive load on the amount and temporal structure of postural sway variability in stroke survivors

    , Article Experimental Brain Research ; Volume 236, Issue 1 , 2018 , Pages 285-296 ; 00144819 (ISSN) Mehdizadeh, H ; Khalaf, K ; Ghomashchi, H ; Taghizadeh, G ; Ebrahimi, I ; Taghavi Azar Sharabiani, P ; Mousavi, S. J ; Parnianpour, M ; Sharif University of Technology
    Springer Verlag  2018
    Abstract
    This study aimed to investigate the variability in postural sway patterns during quiet standing in stroke survivors. The postural sway was measured in 19 stroke survivors, as well as 19 healthy demographically matched participants, at 3 levels of postural difficulty (rigid surface with closed and open eyes, and foam surface with closed eyes), and 3 levels of cognitive difficulty (without a cognitive task, easy and difficult cognitive tasks). Both linear analyses (the amount of postural sway variability, including the standard deviation of the COP velocity in both the anteroposterior (AP) and mediolateral (ML) directions), as well as non-linear analyses [the temporal structure of the COP... 

    Autonomous Skill Acquisition in Reinforcement Learning Based on Graph Clustering

    , M.Sc. Thesis Sharif University of Technology Taghizadeh, Nasrin (Author) ; Beigy, Hamid (Supervisor)
    Abstract
    Reinforcement Learning (RL) is a branch of machine learning that tries to improve agent’s behaviour through interaction with environment and receiving reinforcement signal. As the size of environment increases, decision-making would be more difficult and learning time will increase. On of the main approaches for decreasing learning complexity is to define skills. Skill is a behavioural unit consists of primitive actions. Humans learn and use a lot of skills in their life. Walking, eating, passing the door to reach kitchen and going to airport for travelling are examples of such skills that humans utilize them for daily activities. Agent can learn skills once and then uses them in other... 

    A planar neuro-musculoskeletal arm model in post-stroke patients

    , Article Biological Cybernetics ; Volume 112, Issue 5 , 2018 , Pages 483-494 ; 03401200 (ISSN) Asghari, M ; Behzadipour, S ; Taghizadeh, G ; Sharif University of Technology
    2018
    Abstract
    Mathematical modeling of the neuro-musculoskeletal system in healthy subjects has been pursued extensively. In post-stroke patients, however, such models are very primitive. Besides improving our general understanding of how stroke affects the limb motions, they can be used to evaluate rehabilitation strategies by computer simulations before clinical evaluations. A planar neuro-musculoskeletal arm model for post-stroke patients is developed. The main idea is to use a set of new coefficients, Muscle Significance Factors (MSF), to incorporate the effects of stroke in the muscle control performance. The model uses the optimal control theory to mimic the performance of the CNS and a two-link... 

    The effects of anxiety and external attentional focus on postural control in patients with Parkinson’s disease

    , Article PLoS ONE ; Volume 13, Issue 2 , 2018 ; 19326203 (ISSN) Jazaeri, S. Z ; Azad, A ; Mehdizadeh, H ; Habibi, S. A ; Mandehgary Najafabadi, M ; Saberi, Z. S ; Rahimzadegan, H ; Moradi, S ; Behzadipour, S ; Parnianpour, M ; Taghizadeh, G ; Khalaf, K ; Sharif University of Technology
    Public Library of Science  2018
    Abstract
    Background Although anxiety is a common non-motor outcome of Parkinson's disease (PD) affecting 40% of patients, little attention has been paid so far to its effects on balance impairment and postural control. Improvement of postural control through focusing on the environment (i.e. external focus) has been reported, but the role of anxiety, as a confounding variable, remains unclear. Objectives This study aimed to investigate the influence of anxiety and attentional focus instruction on the standing postural control of PD patients. Methods Thirty-four patients with PD (17 with high anxiety (HA-PD) and 17 with low anxiety (LA-PD)), as well as 17 gender- and age-matched healthy control... 

    1D Simulation of Naturally Fractured Oil Reservoir Flow with High Resolution Central Scheme Using Black-Oil Model

    , M.Sc. Thesis Sharif University of Technology Mojaddam, Mohammad (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    In This work, the performance of a finite volume (FV) numerical method is examined for simulating naturally fractured hydrocarbon reservoir. The dual-porosity approach applied for fracture modeling, and the flow transfer formulated based on a generalized black oil model which is based on matrix formulation, leading to a system of equations prone to degeneracy. This FV high-resolution central scheme numerical method is not sensitive to the choice of CFL number like some of other central schemes and can conveniently handle degenerate equations appearing in the reservoir simulation governing equation. In this effort, one dimension multi phase flow simulated in naturally fractured reservoir and... 

    Study of Capillary Pressure Effect on Multiphase Flow in Hydrocarbon Reservoirs

    , M.Sc. Thesis Sharif University of Technology Biglarian, Hassan (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    One of the most important issues in the petroleum industry, is how to increase the oil production from hydrocarbon reservoirs. The optimum design of an enhanced oil recovery process needs the knowledge on the physical phenomena of the working flow in oil reservoirs. An important aspect of any oil recovery process is the effectiveness of process fluid in removing oil from the rock pores at microscopic scales, in a way that it determines the success or failure of the recovery process. Meanwhile, one of the most important factors on the fluid mobility and as a result the microscopic mobility efficiency is the pressure difference between different phases in narrow paths of porous media. This... 

    Petroleum Reservoir Simulation Using Combination Multi-scale Finite Volume Method and Streamline Method with Gravity Effects

    , M.Sc. Thesis Sharif University of Technology Bordbar, Amir (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    In this thesis the oil reservoir simulation is carried out by using a combination of fast Multi-scale finite volume method and Streamline method considering gravity effects. In this simulation, the governing equations for incompressible fluid flow in porous media are solved using the IMPES (implicit pressure- explicit saturation) viewpoint. Multi- scale method is rapid (equivalent on coarse-scale methods) and accurate (equivalent on fine-scale methods) in solving the pressure field. Using the pressure field obtained through this way combined with Darcy equation make us able to extract the conservative velocity field. In this study, analytical and numerical Streamline methods are used to... 

    Cosmological Black Hole

    , Ph.D. Dissertation Sharif University of Technology Taghizadeh Firouzjaee, Javad (Author) ; Mansouri, Reza (Supervisor)
    Abstract
    In the era of precision cosmology it is desirable to know if the collapse of an overdensity region within a FRW cosmological model leads to a black hole similar to that of Schwarzschild. Even the simple question of an event horizon within a dynamical universe is not a trivial one. This subject of studying collapsing over-densities within an expanding universe is called ”cosmological black holes”. Our aim is to construct such a black hole in the simplest possible scenario and study its similarities and differences to the familiar Schwarzschild one in vacuum. Therefore questions of rotating or charged black holes are not dealt with in our work. We insist, however, that the solution is dynamic... 

    Comparison and Evaluation of the Performance of some Fundamental Models for Simulation of Naturally Fractured Hydrocarbon Reservoirs

    , M.Sc. Thesis Sharif University of Technology Mahmoudi, Siamak (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    Fractured reservoirs show a different behavior from common reservoirs because of the existence of a broad network of fractures. This phenomenon makes it necessary to apply special methods for fractured reservoirs in the procedure of reservoir simulation. Since twenty percent of petroleum content in the world is buried in fractured reservoirs, investigating these reservoirs is of great importance.
    The first step in simulation of these kinds of reservoirs is to come up with a geometrical model which can be used to take the fracture network influence into account. In the course for reaching such an objective, various models have been developed which are based on specific assumptions and in... 

    Simulation of Magnetohydrodynamic Flow in the MWEC Generator Duct Using OpenFOAM Software

    , M.Sc. Thesis Sharif University of Technology Azadi, Ehsan (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    Magnetohydrodynamic (MHD) flow is concerned with the interaction between the magnetic field and electrically conducting fluid flow. In this investigation, the MHD flow in the duct of magnetohydrodynamic wave energy conversion (MWEC) generator was simulated by use of OpenFOAM software. In the MWEC generator the reciprocating motion of ocean waves lead to electrically conducting fluid flow in the duct of this generator. By applying magnetic field perpendicular to this flow, electric current generate in the fluid. This generator has a higher efficiency compared with other ocean wave energy conversion generators. Firstly, to evaluate accuracy and performance of mhdFOAM code of OpenFOAM, three... 

    Numerical Solution Of One-Dimensional Non-Fourier Bioheat Transfer Through Skin Tissue

    , M.Sc. Thesis Sharif University of Technology Fazel, Zeynab (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    Innovations in laser, microwaves, and similar technologies have significantly advanced thermal treatments for diseases or even injuries concerning skin tissue. For a thorough understanding in the underlying mechanisms of bioheat transfer behavior of skin,a1D unsteady non-dimensional hyperbolic model of heat transfer through this tissue with metabolic heat generation which is subject to specific boundary conditions, is solved numerically using the finite difference method. A thermal shock is generated at the base of the tissue, which moves forward with a finite speed. A Numerical solution for a simple one-layer skin tissue is obtained. Then, the effects of various parameters, time step,... 

    Comparison of Transfer Functions in Dual Porosity-Dual Permeability Models in Simulation of 3D Black-Oil Naturally Fractured Reservoirs Using Structured Grids

    , M.Sc. Thesis Sharif University of Technology Mohammadnejad, Hamed (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    In this work, simulation of 3D three-phase naturally fractured reservoirs is studied. Both Dual Porosity and Dual Porosity-Dual Permeability models which are commonly used in commercial softwares such as ECLIPSE and CMG, are utilized. The governing equations include the mass (in Black-oil model) and linear momentum (in Darcy law form) equations, which are converted into pressure equations and a set of transport equations for the saturations and mole fractions of phases. These equations are solved once for the matrix domain and subsequently for the fracture domain. These two set of equations are coupled through transfer functions. The accuracy of computations significantly depends on how... 

    Prediciton of Suspensions Bulk Viscosity Using Immersed Boundary Approach in the Framework of the Lattice Boltzmann Method

    , Ph.D. Dissertation Sharif University of Technology Farnoush, Somayeh (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    In this study, bulk viscosity of suspensions is predicted using numerical simulation.The elaborated numerical method consists of the lattice Boltzmann (LB) method for fluid matrix simulation and the immersed boundary (IB) method for solid boundary implementation. In order to successfully implement the IB method in the frame-work of the LB method, two important challenges, which are body force modeling in the LB method and numerical velocity slip on solid boundaries, are discussed. As a first challenge, body force modeling in the LB method is studied by using a uni-fied framework which has been devised in this study. Using this unified framework,firstly, errors of different body force... 

    Comparison of Transfer Functions in Dual Porosity-Dual Permeability Model in Simulation of Naturally Fractured Reservoirs in Two Phase Water-Oil Systems

    , M.Sc. Thesis Sharif University of Technology Asadbegi, Mohsen (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    In this study, simulation of two-phase water-oil compressible flow in naturally fractured reservoirs is studied. The studied reservoir has a 1D and horizontal ge-ometry that its properties such as porosity and permeability are homogeneous.Dual Porosity and Dual Porosity-Dual Permeability models are employed for simulation of reservoir. Reservoir descriptive equations are conservation of mass and momentum. Conservation of momentum equation is simplified by Darcy law and two-phase fluid flow is simulated with Black-oil model. Discretization of equations is done by finite volume method. In order to solve the equations of two-phase compressible fluid flow, the so-called IMPES (Implicit Pressure... 

    An Implicit Numerical Method for Simulation of Gas Production and Recycling in Gas-condensate Reservoirs Using a Two-phase Compositional Model

    , M.Sc. Thesis Sharif University of Technology Asgari, Milad (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    In this project, a response of a single well in a gas condensate reservoir has been investigated by compositional modeling and implicit numerical method. The most significant goals of this paper are as follows: 1- Examination of the flow produced in a gas condensate reservoir in constant pressure or mass rate. 2- Investigation of variables affecting the productivity of reservoir. 3- The study of effect of injection and gas cycling to the well on the production. A three-zone model has been used in this study as if there is only gas phase in the third and second zones. Condensation occurs since the pressure drops below the dewpoint pressure in the second zone; however, gas phase is only... 

    Uncertainty Quantification of Two Phase Immiscible Water Oil Flow

    , M.Sc. Thesis Sharif University of Technology Mahmoudi, Mehrdad (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    In this project، the immiscible two phase flow of oil-water in the absence of gravity in the two dimensional domain is investigated. The uncertainty quantification of pressure and saturation of fluid in the reservoir are calculated by the methods of statistical moment equation (presented by Tchelepi) and probabilistic collocation method combined with Karhunen Loeve expansion (presented by Heng Lee). Then the results are compared with Monte Carlo simulation. Matlab Reservoir Simulation Toolbox is used for flow simulation. The main problem based on Tchelepi’s work[56[ ، is a horizontal two dimensional problem that there is two injection and production wells at the two end point grids (a... 

    Optimization of a serpentine model for low-dispersion flows in micro channel turns

    , Article 5th International Conference on Perspective Technologies and Methods in MEMS Design, MEMSTECH 2009, Lviv-Polyana, 22 April 2009 through 24 April 2009 ; 2009 , Pages 136-140 ; 9789662191066 (ISBN) Fathollahi, E ; Afsharikia, S ; Taghizadeh Manzari, M.T ; Sharif University of Technology
    2009
    Abstract
    Chip-based micro fluidic separation systems often use serpentine channels to attain long separation lengths in a compact area. Such designs suffer from the dispersion, mostly 'racetrack' effect, due to the bends in the micro channels. The main goal of this paper is obtaining a model which has minimal racetrack in a serpentine geometry. A numerical analysis leads us to an optimized model which is different from previous attempts in this field. Our model uses modified turn radii, optimal length between bends with a constant zeta-potential boundary condition and a constant width through micro channel turns. It is shown that traveling fluid in this geometry has minimal dispersion as well as... 

    Simulation of Flow in Anisotropic Heterogeneous Oil Reservoirs Using Compositional Model and Cell-Based Unstructured Grid

    , Ph.D. Dissertation Sharif University of Technology Moshiri, Mojtaba (Author) ; Taghizadeh Manzari, Mehrdad (Supervisor)
    Abstract
    Reservoir simulation is a useful tool for efficient reservoir management and protective exploitation of non-renewable hydrocarbon resources as the main supplier of development programs in the country. Due to the nature of underground hydrocarbon reservoirs, the simulation faces several challenges, both in rock and fluid parts. These challenges should be overcome in order to provide reliable results from simulations. One of the major challenges pertaining to rock, is large discontinuous variations accompanied by anisotropy of rock permeability fields which causes numerous problems when governing equations are solved numerically. A viable numerical procedure shall account for complex reservoir...