Sharif Digital Repository

With the increasingly collected biological data, appropriate usage of this data is of great importance for understanding and predicting biological systems and has been the aim of experiments and data collections. A famous category of biological data is known as “omics” which refers to transcriptomics, proteomics, metabolomics, and fluxomics, from different cells or tissues in various media and conditions. This set of data is regularly used for tasks such as studying cells and organisms, understanding cell states, cancer prediction, etc. and is of great importance in Systems Biology.In this thesis, we concentrate on studying cells or organisms using such data, where during that process, we... 

This thesis extends a probabilistic framework for evaluating the seismic resilience of communities by probabilistic modeling of the telecommunication infrastructure failure and recovery along with its interdependencies with other infrastructures. This framework, Rtx, that is being extended under continuous development at Sharif University of Technology, is based on modeling the community state from hazard incident until complete recovery by a combination of risk and agent-based simulation models. In this thesis the framework is extended with telecommunication infrastructure models. This infrastructure is modeled by developing a library of probabilistic models to predict damage to network... 

Current study reports a state-of-the-art approach for synthesis of nanocatalyst based on Oxo-vanadium Schiff base complex which itself is, covalently, immobilized on core-shell magnetic nanoparticles of silica-modified magnetite (Fe3O4@SiO2) and the substantial potential it offers as heterogeneous catalyst in selective oxidation of sulfides.Synthesized materials and complexes in this project were characterized by means of modern spectral devices such as FT-IR, XRD and SEM.Unlike routine process of the preparation of heterogeneous catalysts that requires further modification of the core-shell nanoparticles with capping agents, here we have been capable of cutting some time-consuming steps... 

In current research, two zirconium-based metal-organic frameworks, MIP-202 (Zr) and UIO-66(CO2H)2 were employed as catalysts in the epoxy ring-opening reactions by amino and alcoholic nucleophiles. Firstly, these metal-organic frameworks were prepared under mild synthetic conditions and then characterized by means of spectral techniques such as X-ray diffraction (XRD), nuclear magnetic resonance spectroscopy (NMR), Fourier transform infrared spectroscopy (FT-IR), electron microscopy Scanning (SEM) and X-ray energy diffraction (EDAX) spectroscopy were confirmed. Finally, their catalytic activity in epoxy ring-opening reactions was investigated and in to determine optimal conditions, the... 

In this research, an attempt was made to increase the efficiency and effectiveness of the targeted and controlled release systems of the anticancer drug (doxorubicin) by using inorganic and organic compounds as well as inorganic-organic hybrids. For this purpose, a whole class of aluminum fumarate metal-organic frameworks-based and reduced-graphene oxide nanocarriers were synthesized and using Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction spectroscopy (XRD), scanning electron microscope (FESEM) and atomic force microscope (AFM) analysis were characterized, and their nano-composites based on organotin-complexes with the approach of achieving a stable drug delivery system,... 

This thesis proposes a probabilistic framework for evaluating and enhancing the community recovery process following an earthquake occurrence. This framework serves as a recovery decision support tool, aiming to enhance community resilience through the optimal allocation of limited available resources following a disaster occurrence. To this end, Bayesian network and agent-based simulation are integrated, each of which forming one of the modules of the proposed framework. The first module, namely, the Bayesian network, leads to situational awareness of the status of the community after the earthquake by fusing data from various sources. The data, such as the earthquake event characteristics... 

Magnesium alloys as the lightest structural alloys, have a strong potential for improving the energy efficiency of different transportation systems such as automobiles, aerospace and electronics due to their high strength to weight ratio. Welding plays a crucial role as a foundational manufacturing technology. Hence, the extensive utilization of materials is greatly impacted by their ability to be welded.These alloys are highly susceptible to hot cracking such as liquation cracking during the fusion welding processes.Various mechanisms play a role in the occurrence of hot cracking, but the constitutional liquation of the coarse eutectic mg17al12 intermetallic phase is accountable for the... 

With the increasing number of elderly people as a proportion of the total population in the world and the aging of the world's population, the need for medical care has increased. On the one hand, most of the elderly population have chronic diseases such as diabetes, hypertension, etc., which do not require hospitalization in healthcare centers, but they need to monitor their health status. Given the progress of technology, the measurement of vital body signals has been made possible with non-invasive methods. In this thesis, an attempt has been made to provide a wearable and portable solution for the measurement, monitoring, and collection of vital signals based on the Internet of Things... 

This study proposes a probabilistic approach to prioritize a collection of buildings in a region for seismic retrofit based on regional risk analysis. Risk in this context is the exceedance probability of total economic and social losses, which include both direct and indirect consequences resulting from building damage. The prioritization criterion is determined by the benefit-to-cost ratio of retrofit, where the benefit is measured by the reduction of seismic risk achieved through retrofitting. Hence, the buildings are analyzed both in their current state and after retrofit to compute the risk measure, i.e., the mean total loss. Buildings that yield the highest reduction of the risk... 

This thesis presents a comprehensive probabilistic framework for community seismic resilience assessment considering all major infrastructures and their dependencies in an integrated analysis. The infrastructures that are modeled in this research include the buildings portfolio, electric power system, potable water system, natural gas system, telecommunication system, transportation system, healthcare system, and businesses. In fact, this research builds upon past studies, each of which focused on assessing the resilience of individual infrastructures. Integrating resilience analysis of all infrastructures allows for modeling the effects of their dependencies on robustness, rapidity, and... 

In this thesis, An All Digital Frequency Synthesizer for use in RF applications is designed in 180nm CMOS. Different blocks such as Phase detector, Loop filter and Loop counter is designed. Finally, an All Digital Frequency Synthesizer is modeled using this circuits and an Digitally controlled oscillator model and is designed for GSM. In this thesis a new method is proposed to noise shape the quantization noise of the time to digital converter. The Time to Digital Converter has 7mW power consumption for 0ns to 1ns input range. Using this noise shaping method, quantization noise is reduced about 20dB. Also, limit cycle related spurs is reduced significantly using first order and second order... 

Nowadays, general electronic devices such as computers, notebooks, cellular phones and etc. are supporting Bluetooth, RFID and Zigbee standards. By integrating all of RF sections of mentioned standards, total power consumption, occupied area and total cost and price will be decreased. RF devices communications with maximum bandwidth and data rate with minimum power consumption are the main purposes in designing RF and digital building blocks. Bluetooth and Zigbee standards are applied for networking the desired RF devices. RFID standard is providing automatic identifications, item tracking and tracing, item management and inventory. RFID standard makes the communication between Tags and... 

To synthesizeFe3O4@SiO2 core-shellnanoparticles,at first,Fe3O4 magnetic nanoparticle synthesisedby usingcoprecipitation method.Then tetraethyl orthosilicate (TEOS) was used to coverthe surface of this nanoparticle with layer of silica. In the next step, the surface of Fe3O4@SiO2 core-shellnanoparticlesfunctionalized by NO-bidentate and ONO-tridentate ligands. Finally the functionalized nanoparticle coordinated to oxovanadium(IV) to achieve Fe3O4@SiO2@NO-VO2+ and Fe3O4@SiO2@ONO-VO2+nanocatalysts for selective oxidation of sulfides to corresponding sulfoxide and oxidation of alkene. FT-IR, 1HNMR, 13CNMR, SEM, VSM and ICP analysis were used for characterization of this nanocatalysts. This... 

This project introduces a topology enabling a Low-Noise Amplifier (LNA) not only to attenuate the unwanted signals at the input stage but also to satisfy the input matching requirement in an ultra wide frequency band. Moreover, a single ended to differential signal conversion method is proposed. This method employs a noise reduction idea, so it has a lower noise figure compared to the other introduced methods with the same purpose. The introduced methods have been utilized in designing two 0.18μm reconfigurable CMOS LNAs. One of the designed LNAs covers 2.3-3.6 GHz band width and the other one covers the UHF (470-860MHz) band. Stringent sensitivity requirement, presence of strong in-band... 

In this project a novel molybdenum(VI) complex with tridentate Schiff base ligand which is soluble in water was synthesized and characterized. In the first step of complex synthesis, chloromethylation of salicylaldehyde was carried out and then, corresponding pyridine salt prepared in the second step. Ligand N-[(3-pyridinium chloride) salicylidene]-2-aminophenol was formed by reaction with aminophenol. In the presence of MoO2(acac)₂ the final product, cis-dioxo(N- (3-pyridinumchloride)salicylidene]-2-aminophenolato)ethanol olybdenum(VI) complex synthesized. The complex was characterized by CHN elemental analysis and spectroscopic methods UV, NMR and FT-IR.We used a high-yield (80-98%) and... 

In this study, Al-5052 aluminium alloy sheet was lap joined to aluminium clad steel sheet using pulsed gas tungsten arc welding and Al-Si filler metal. Effect of heat-input, thickness of clad layer and frequency were investigated on the formation of intermetallic reaction layer, microstructure of the weld seam and shear strength of the joints are explored. Stress analysis in weld is also used in order to justify the fracture location in the welds the microstructure and shear-tensile strength of the welds (joining with A1-1050 clad layer with two thickness of 350 μm and 1000 μm). Before welding, aluminum clad steel sheets were produced by roll bonding and 450 °C annealing temperature and 90... 

In this project, a new magnetically recoverable nanocatalyst was developed by immobilizing of vanadyl acetylacetonate, [VO(acac)2], onto surface of silica coated magnetite nanoparticlest that modified by reaction between 3-aminopropylthriethoxy silane and 5-bromosalicylaldehyde. In the first step, magnetite cores were synthesized by co-precipitation method and coated by tetraethyl orthosilicate (TEOS) and modified by 3-aminopropyltriethoxy silane to provide a precursor for Schiff base condensation reaction. In the next step, amino-functionalized silica coated magnetite nanoparticles were reacted by 5-bromosalicylaldehyde to formation a Schiff base moiety onto surface of magnetite coated... 

Resistive pulse sensing (RPS) has proved to be a viable method for detection and characterization of micro and nano particles. This method works based on ionic current variation inside nanopores. Modern fabrication methods have introduced different nanopore geometries for resistive pulse sensors therefore studing the effects of geometry on sensing performance of nanaopores is important. Numerical simulation has been used to study a wide variation of nanopore’s geometry configurations and study the physics behind this phenomena. Based on the results, numerical simulation could be used as a fast and easy tool for size determination for nanopore. To compare the sensing performance of different... 

This study aims to design and develop procedures, forms, and tools for post-earthquake reconnaissance. The current procedure for data collection is based on the sending of groups to identify the dimensions of the evidence and its consequences by the executive and responsible institutions. Studying and reviewing the reports that have been produced by this method shows that there is not any systematic mechanism for collecting data on a wide scale and from all aspects of the evidence. The limited data collected by the executive and responsible institutions are scattered in the reports and are less documented in the database. Therefore, it is necessary to collect big data on the severity and...