Sharif Digital Repository

Optical tweezers consist of a tightly focused laser beam. Particle with refractive index grater than that of the surrounding medium are eligible for optical trapping. This device is used for measuring forces from pico-newton to nano-newton, and displacements from nanometer to micrometer. In biopolymers, for example, it is used for studying the elasticity of DNA molecules, mechanical properties of cell membrane; and also in Microfluidics, it can is used for mixing two liquids flowing in a micro-channel by rotating a trapped particle. In general, physics of optical tweezers (or interaction of the trapped particle with the tightly focused laser beam) is treated in three different regimes:1)... 

Red blood cells are one of the most important parts of blood and their mechanical properties are so important in some diseases. Red blood cell is mostly consisted of membrane, cell skeleton, and cytoplasm which contains hemoglobin proteins. Studying these properties separately not only could give us pieces of information about cell mechanics, but also reveals a way to predict their behavior after illnesses. Optical tweezers as a tool, which can produce and measure Piconewton to Nanonewton forces, has been interesting in red blood cell parts' studying. In this thesis, at first hemoglobin is taken out gradually by using Saponin (which is enable to make some pores in the membrane) and the... 

Blood is one of the most important fluids in the human body, consisting of three parts: red blood cells, white blood cells and platelets. The mechanical properties of red blood cells are important in many diseases. The study of viscosity and other mechanical properties of red blood cells in recent years has attracted the attention of scientists in this field. The mechanical properties of red blood cells are related to the outer membrane and its cytoskeleton, and the study of these components can predict the behavior of red blood cells in diseases. The thyroid gland is located in front of the neck and secretes hormones that control many chemical processes in different parts of the body.... 

Fatigue is one of the most common failure modes that reduce the structural integrity of asphalt pavements. Dynamic tests are used as fatigue performance indicators for asphalt mixture. However, these tests are expensive and require special equipment and set up. At this research, the main goal is to develop a fuzzy model which is more efficient than the existing regression model for prediction of the fatigue life. A database from the available data from various research was compiled. For each model, a comparison between Fuzzy and regression output by actual outputs was done and it was seen that the fuzzy modeling can predict fatigue life very closely. Finally, the required software for this... 

Accurate prediction of pavement performance is essential to a pavement infrastructure management system. Selection of the prediction model is based on the extent of available data, assumptions used in performance modeling, ease of use and management purposes. Therefore, two methods were proposed in this thesis based on the assumptions of availability and unavailibility of accurate data. The first method presents a two-stage model to classify and accurately predict the performance of a pavement infrastructure system. Sections with similar characteristics are classified into groups using a support vector classifier (SVC). Then, a recurrent neural network (RNN) is utilized to predict... 

Asphalt concrete is a composite mixture of three phases; aggregate, bitumen and air void. Stress and strain distributions obtained from macroscopic modeling yield different results due to distinctly different mechanical properties of the above-mentioned phases. In this study a more exact analysis of the stress and strain, were carried out by considering the mixture as a two-phase composite; aggregate and mastic phases. Asphalt concrete was considered a composite material consisted of sand mastic and aggregate. Aggregate and mastic phases were separated and response of the loaded asphalt mixture was investigated. Aggregates finer than 2.36 mm in diameter, filler and bitumen consist the... 

Binder modification, to improve the rheological properties and meet the standard requirements, is a common practice. The modification is usually done by adding polymers like Ethylene Vinyl Acetate (EVA) and Styrene Butadiene Styrene (SBS), waste materials like crumb rubber, or acids like Poly phosphoric acid (PPA) or by air blowing techniques. High temperature rheological properties of modified binders are usually improved by using polymers while the low temperature rheological properties mostly depend on the original binder. Therefore, the rheological properties at low temperatures do not show clear improvements in the modified binder compared to the original binder. This indicates that a... 

Most available methods which are well able to improve or dewater coarse soils have little success dealing with fine soils and clays and using these methods to dewater clays needs great amount of time and money. Electrokinetic Geosynthetic is one of new methods that have had a promising future. Regarding the importance and tremendous usage of dewatering in fine soils, the efficiency of electrokinetic geosynthetic method in dewatering fine soils has been taken under the consideration in this research. Following laboratory experimentation, numerical modeling of this process has been done. In this research some laboratory test has been done on kaolinite clay and the effects of pH of specimen,... 

Modification by crumb rubber is a useful means of improving the resistance of asphalt binders and mixtures against rutting, fatigue cracking, and low temperature cracking. Increase binder viscosity and decrease stability at high temperatures are accompanied by most modifiers, and crumb rubber is no exception. Recent research efforts have shown that development of cross bonds across polymer chains and sulfur can improve the storage stability of modified binders. Also, WMA additives can considerably decrease the binder viscosity. This research showed that addition of small amount of sulfur during the crumb rubber modification can improve the workability and storage stability of this binder.... 

Asphalt concrete is a heterogeneous and multi-phase material that consists of aggregates, asphalt binder, and pores. These components create a complex microstructure. There is no consensus on how to quantify the microstructure and the required parameters from two-dimensional images. The load transfer can be managed by aggregate-aggregate or aggregate-mastic interactions that depend on the gradation, aggregate internal structure, and asphalt binder viscoelastic properties. The most important internal structure indices affecting the behavior of HMA are aggregate orientation, contact orientation, contact length, and number of contact points. In this research, the influence of aggregate... 

Human eye is one of the most important organs of the human body. Performance of the eye may be decreased by some anomalies such as myopia, hyperopia, astigmatism, cataract, glaucoma, etc. There are variety of techniques to treat eye anomalies including surgery, using optical elements and training methods.The easiest way of treating refractive errors of the eye, is to use optical elements such as contact lenses, intraocular lenses and glasses. In the case of cataract, Crystalline lens loses its opacity and should be replaced by artificial lens. The best choice is Fresnel lens which has lower weight and thickness than refractive lenses.Fresnel lens is a diffractive optical element which uses... 

The numerical simulation of asphalt concrete and pavement has gained considerable attention in recent decades. Information about the response of asphalt pavements during construction and in-service traffic loading is required by pavement specialists for improvement of pavement analysis and design methods. The goal of this study was to propose a constitutive relationship and a numerical modeling method for asphalt concrete compaction in the laboratory and in situ. Asphalt binders exhibit rate-dependent viscoelastic and viscoplastic mechanical behavior in asphalt concrete. The current study examined the viscoelastic and viscoplastic mechanical behavior of asphalt concrete under various loading... 

Nowadays, according to increasing development of construction industry in the world especially in the building area, the need to use technology and innovation for fabrication and maintenance of this industry has increased. And this fact becomes apparent that the use of traditional systems of construction isn’t tailored the countries’ requirements anymore. One of the construction industry’s limitations is the restrictions on architectural designs reys. The columns are among the most important components of structure and have a major role in bearing all gravity and lateral loads and transferring them to the foundation. The failure or destruction of the components in the structure under applied... 

This research is conducted aiming to analyze the Customer Knowledge Management and Customer Interaction Management in CRM in Iran Insurance Industry. Cheng and Yang Model was utilized for analyzing the two aforementioned parameters. The current research is descriptive and survey was conducted for data gathering. The research population involves 80 employees working in Technical and Marketing segments of the 5 insurance companies (Iran, Asia, Alborz, Dana, Parsian). The dependent parameter is Customer Interaction Management and the independent parameter is Customer Knowledge Management. The data collected from conducting the survey is analyzed by LISREL software and with Structural Equation... 

In the presence of spatially non-uniform electric field, a dielectric object can experience a translational force which is known as Dielectrophoresis (DEP) force. DEP is one of the most applicable methods in sorting mechanism of different biological cells. Moreover accurately measuring the DEP force in single cell level can lead to a valuable knwoledge about the electrical properties of various cells.In this thesis, first, the other electrokinetic forces in which the Electro-Osmosis (EO) force is the important one, have to be eliminated. Regarding that this effect is strongly dependent on the frequency of external E field, we have applied the external electric field at appropriate frequency... 

Properties of viscoelastic of biopolymers have important role in cells structure; for example: cell motility depends on viscoelastic propertie of Actin polymer. therefore according to its importance ,in this thesis we intend to examine the viscoelastic modulus using Optical tweezers and dissipation theorem.this method is benefits than methods of active microrheology. for example this method can be used for low concentrations; because in the low concentrations, the exerting force will cause changing in the state of matter that here we investigate destructive force effect. we investigate viscoelastic of water for method accuracy then obtain viscoelastic of Kelcogel  

The most important researchers’ purposes in superconductivity are achievement of the room temperature superconductivity and to understand the high temperature superconductivity mechanism. Researchers’ goal in to increase the transition temperature by applying pressure, changing oxygen content, different doping, and changing stoichiometry in the families of the high temperature superconductors. In this research, which has been carried out in the Magnet Research Laboratary of Sharif University of Technology, samples of Y3Ba5Cu8O18, Gd3Ba5Cu8O18, and Pr3Ba5Cu8O18 have been synthesized by the standard solid-state reaction technique, the structure, electrical and magnetic properties of the... 

In the present research a two stage supply chain is considered. In its first echelon, there is a producer that produces both perfect and defective items. Defective items are reworked by producer and no defective item is produced during the reworking process. There is a buyer in second echelon of the supply chain that faces constant demand and orders fixed batches in fixed periods to the producer. So in each complete cycle of production, multiple orders are received from buyer. Two different policies for reworking are investigated in this research. In the first policy, reworking is done in the same cycle that producing is conducted but in the second one all defective items that are produced...