Loading...
Search for:
danesh-manesh--habib
0.051 seconds
Total 145 records
Specific targeting delivery to MUC1 overexpressing tumors by albumin-chitosan nanoparticles conjugated to DNA aptamer
, Article International Journal of Pharmaceutics ; Volume 515, Issue 1-2 , 2016 , Pages 607-615 ; 03785173 (ISSN) ; Mohammadi, A ; Atyabi, F ; Nabavi, S. M ; Ebrahimi, S. M ; Shahmoradi, E ; Shiri Varnamkhasti, B ; Ghahremani, M. H ; Dinarvand, R ; Sharif University of Technology
Elsevier B.V
2016
Abstract
Chitosan-coated human serum albumin nanoparticles were functionalized by MUC1 aptamer to obtain a selective drug carrier toward cancers overexpressing MUC1. The negative charges of albumin nanoparticles were shifted to positive charges by surface modification with chitosan, and MUC1 was conjugated through an acrylate spacer. The cytotoxicity of targeted nanoparticles was significantly more than non-aptamer nanoparticles, and also the chitosan-coated nanoparticles had more cytotoxic effects than the negatively charged albumin nanoparticles. The IC50 of targeted nanoparticles was 28 and 26% of free paclitaxel in MCF7 and T47D cells at 48 h, respectively. Confocal laser scanning electron...
Cyclometalated platinum(II) complexes of 2,2′-bipyridine N-oxide containing a 1,1′-bis(diphenylphosphino)ferrocene ligand: structural, computational and electrochemical studies
, Article Dalton Transactions ; Volume 46, Issue 6 , 2017 , Pages 2013-2022 ; 14779226 (ISSN) ; Fereidoonnezhad, M ; Niazi, M ; Mosavi, S. T ; Habib Kazemi, S ; Kia, R ; Shirkhan, S ; Abdollahi Aghdam, S ; Sharif University of Technology
Royal Society of Chemistry
2017
Abstract
The preparation and characterization of new heteronuclear-platinum(ii) complexes containing a 1,1'-bis(diphenylphosphino)ferrocene (dppf) ligand are described. The reaction of the known starting complex [PtMe(κ2N,C-bipyO-H)(SMe2)], A, in which bipyO-H is a cyclometalated rollover 2,2'-bipyridine N-oxide, with the dppf ligand in a 2:1 ratio or an equimolar ratio led to the formation of the corresponding binuclear complex [Pt2Me2(κ2N,C-bipyO-H)2(μ-dppf)], 1, or the mononuclear complex [PtMe(κ1C-bipyO-H)(dppf)], 2, respectively. According to the reaction conditions, the dppf ligand in 1 and 2 behaves as either a bridging or chelating ligand. All complexes were characterized by NMR spectroscopy....
Pressure Transient Analysis of Variable-rate Well Test Data
, Ph.D. Dissertation Sharif University of Technology ; Rashtchian, Davood (Supervisor) ; Van den Hof, Paul (Supervisor) ; Jansen, Jan Dirk (Supervisor)
Abstract
This study presents a novel perspective on pressure-transient analysis (PTA) of downhole-pressure and flow-rate data by use of system-identification (SI) techniques as widely used in advanced process engineering. Key features of the algorithm are that it considers the classic PTA process from a system-theoretical perspective; derives the causal structure of the flow dynamics; proposes a method to deal with continuously varying pressure and flow-rate signals contaminated with correlated noise, which estimates physical reservoir parameters through a systematic matching procedure in the frequency domain; and can cope with arbitrary (i.e., not necessarily piecewise constant) flow-rate signals....
The isaac newton telescope monitoring survey of local group dwarf galaxies. iv. the star formation history of andromeda vii derived from long-period variable stars
, Article Astrophysical Journal ; Volume 910, Issue 2 , 2021 ; 0004637X (ISSN) ; Saremi, E ; Javadi, A ; Noori, M ; Van Loon, J. T ; Khosroshahi, H. G ; McDonald, I ; Alizadeh, M ; Danesh, A ; Gozaliasl, G ; Molaeinezhad, A ; Parto, T ; Raouf, M ; Sharif University of Technology
IOP Publishing Ltd
2021
Abstract
We have examined the star formation history (SFH) of Andromeda VII (And VII), the brightest and most massive dwarf spheroidal (dSph) satellite of the Andromeda galaxy (M31). Although M31 is surrounded by several dSph companions with old stellar populations and low metallicity, it has a metal-rich stellar halo with an age of 6-8 Gyr. This indicates that any evolutionary association between the stellar halo of M31 and its dSph system is frail. Therefore, the question is whether And VII (a high-metallicity dSph located ∼220 kpc from M31) can be associated with M31's young, metal-rich halo. Here we perform the first reconstruction of the SFH of And VII employing long-period variable (LPV) stars....
The power of environmental observatories for advancing multidisciplinary research, outreach, and decision support: the case of the minnesota river basin
, Article Water Resources Research ; Volume 55, Issue 4 , 2019 , Pages 3576-3592 ; 00431397 (ISSN) ; Dolph, C ; Baker, A ; Bevis, M ; Cho, S. J ; Czuba, J. A ; Dalzell, B ; Danesh Yazdi, M ; Hansen, A. T ; Kelly, S ; Lang, Z ; Schwenk, J ; Belmont, P ; Finlay, J. C ; Kumar, P ; Rabotyagov, S ; Roehrig, G ; Wilcock, P ; Foufoula Georgiou, E ; Sharif University of Technology
Blackwell Publishing Ltd
2019
Abstract
Observatory-scale data collection efforts allow unprecedented opportunities for integrative, multidisciplinary investigations in large, complex watersheds, which can affect management decisions and policy. Through the National Science Foundation-funded REACH (REsilience under Accelerated CHange) project, in collaboration with the Intensively Managed Landscapes-Critical Zone Observatory, we have collected a series of multidisciplinary data sets throughout the Minnesota River Basin in south-central Minnesota, USA, a 43,400-km2 tributary to the Upper Mississippi River. Postglacial incision within the Minnesota River valley created an erosional landscape highly responsive to hydrologic change,...