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    A Novel Digital Dentistry Platform Based on Cloud Manufacturing Paradigm

    , Ph.D. Dissertation Sharif University of Technology Valizadeh, Siavash (Author) ; Houshmand, Mahmoud (Supervisor) ; Fatahi Valilai, Omid (Supervisor) ; Vasegh, Zahra (Supervisor)
    Abstract
    This thesis has developed a novel platform for digital dentistry which facilitates the interoperability among different digital components and improves digital workflow in a collaborative environment. The platform is inspired by the cloud manufacturing paradigm for enabling the interoperability and collaboration management and also applies the DICOM standard to improve the integration for the coordination among the different stakeholders for better sharing of their resources while they are geographically distributed. The paper has proposed the application of the PACS concept to include design, implant planning, process planning and production workstations. The paper has conducted a... 

    Design and Prototyping of an Axial Flux Resolver for Reduction of Estimated Position Error

    , Ph.D. Dissertation Sharif University of Technology Alipour-Sarabi, Ramin (Author) ; Oraee Mirzamani, Hashem (Supervisor) ; Nasiri-Gheidari, Zahra (Supervisor)
    Abstract
    Providing a precise estimation of the position of a moving element is one of the requirements of many position control systems. Resolvers, as electromagnetic sensors, are one of the most suitable options for use in harsh environments with high thermal and mechanical stresses and high contamination. Although resolvers are the most reliable solution for sensitive applications in stressful environments, they are less accurate in normal operating conditions than optical encoders. In this regard, many efforts have been made to reduce the estimated position. Most of the studies have focused on modifying the electronic converter structure, which is responsible for processing the output signals of... 

    Investigation of the Effects Of Microbially-Induced Calcium Carbonate Precipitation on the Soil-Water Retention Curve and Changes of Small Strain Shear Modulus of Unsaturated Sand During Drying Path

    , M.Sc. Thesis Sharif University of Technology Jahanbakhsh, Yashar (Author) ; Pak, Ali (Supervisor) ; Khosravi, Ali (Supervisor) ; Ghobadi Nejad, Zahra (Supervisor)
    Abstract
    Microbially-induced calcium carbonate precipitation is a low-cost, environmentally friendly, novel ground improvement technique that has received much attention in recent years. Most studies on biological soil stabilization have investigated the mechanical and hydraulic behavior of soils in dry and saturated conditions. However, the behavior of soils stabilized by this method in the unsaturated state should be of immense concern through the extent of unsaturated soils in nature. Therefore, this study aims to investigate the effects of microbially-induced calcium carbonate precipitation on the soil-water retention curve and changes of small strain shear modulus of unsaturated cemented and... 

    Biodecolourization and Biodetoxification of Dye-containing Wastewaters from Textile Dyeing by the Native Fungal Strain Phanerochaete Chrysosporium and Trametes Species

    , M.Sc. Thesis Sharif University of Technology Alimohammadi, Fatemeh (Author) ; Borghei, Mehdi (Supervisor) ; Mosavi, Abas (Supervisor) ; Ghobadi Nehad, Zahra (Co-Supervisor)
    Abstract
    Treatment of Wastewater of textile industries has been always challenging due to the high organic matter which is a suitable substrate for the growth of microorganisms. Also, discharge of wastewater into the open water causes water adsorbing more sunlight, raising water temperature and therefor decreasing dissolved oxygen. In addition, the acidity of wastewater decreases the quality of agricultural soil. Among wastewater treatment methods, biological methods are cheaper, environment friendly, and produce less by product. Among all the microorganism responsible for biological treatment, fungi and enzymes are more applicable. Especially white-rot fungi are the most effective microorganism to... 

    Synthesis, Characterization and Applications of Antibacterial Metal-Organic Framework Nanocomposites for Water Remediation

    , M.Sc. Thesis Sharif University of Technology Talebi Deylamani, Sara (Author) ; Borghei, Mehdi (Supervisor) ; Yaghmaei, Soheila (Supervisor) ; Ghobadi Nejad, Zahra (Co-Supervisor)
    Abstract
    Contaminants in drinking water, including microbial contaminants, have a great impact on the health of people in the community and can seriously threaten public health. In recent years, diseases caused by pathogenic bacteria due to the consumption of contaminated water have led to many deaths. As a result, water treatment has been one of the most important human concerns. Among the new water treatment technologies, metal-organic(MOF) frameworks are a new generation of porous materials that have properties such as high surface area, water stability and functionality due to their dual structure. As a result, they are widely used today in various scientific fields, including water purification.... 

    Theoretical Investigation of Hydrogen Bonding Effects on Interaction of Metal Nanoclusters with Histidine, Oxidation of Olefins by MnO4– & Acidity Enhancement of Alcohols

    , Ph.D. Dissertation Sharif University of Technology Jebeli Javan, Marjan (Author) ; Fattahi, Alireza (Supervisor) ; Mahmoodi Hashemi, Mohammad (Supervisor) ; Jamshidi, Zahra (Supervisor)
    Abstract
    This thesis is divided into three parts: In part I, interactions of neutral and anionic forms of histidine with coinage metal nano clusters M3 (M = Au, Ag and Cu) are investigated. Results demonstrate that nonconventional M…H-O hydrogen bonds and M-X bonds (X = N, O) play stabilization roles in interactions of histidine and metal nano clusters. Presence of negative charge in ligand leads to increase of binding energy of complexes. In the next step, the effects of coinage metal nano clusters on the gas-phase acidity of weak organic acid (histidine) have been explored. The acidity of isolated histidine is compared with the acidity of its Au3–, Ag3– and Cu3–complexed species. Moreover, pKa... 

    Isolation and Identification of Native Microorganisms Capable of Biological Degradation of Microplastics and Evaluation of its Performance in the Degradation of These Microplastics

    , M.Sc. Thesis Sharif University of Technology Kashisaz Shahriyar (Author) ; Yaghmaei, Soheila (Supervisor) ; Ghobadi Nejad, Zahra (Supervisor) ; Hamzehluoyan, Tayebeh (Supervisor)
    Abstract
    In recent years, non-biodegradable microplastics (MPs), which cause a lot of pollution in the environment, have become a major concern worldwide. Due to their small size and large surface area, these plastic particles have a great ability to be absorbed into biological cells. Due to their hydrophobic surface, these particles have the ability to absorb pollutants such as heavy metals, toxic medicinal substances, softeners, etc. Microplastics are usually persistent in the environment, allowing them to be transported along the food chain. Research on the degradation of microplastics is focused on biological and non-biological approaches. To date, microorganisms such as algae, fungi, and... 

    MicroRNA profiling reveals important functions of miR-125b and let-7a during human retinal pigment epithelial cell differentiation

    , Article Experimental Eye Research ; Volume 190 , 2020 Shahriari, F ; Satarian, L ; Moradi, S ; Sharifi Zarchi, A ; Günther, S ; Kamal, A ; Totonchi, M ; Mowla, S. J ; Braun, T ; Baharvand, H ; Sharif University of Technology
    Academic Press  2020
    Abstract
    Retinal pigment epithelial (RPE) cells are indispensable for eye organogenesis and vision. To realize the therapeutic potential of in vitro-generated RPE cells for cell-replacement therapy of RPE-related retinopathies, molecular mechanisms of RPE specification and maturation need to be investigated. So far, many attempts have been made to decipher the regulatory networks involved in the differentiation of human pluripotent stem cells into RPE cells. Here, we exploited a highly-efficient RPE differentiation protocol to determine global expression patterns of microRNAs (miRNAs) during human embryonic stem cell (hESC) differentiation into RPE using small RNA sequencing. Our results revealed a... 

    Design and Fabrication of Bioactive Nano Fibrous Scaffold for Central Nervous Tissue Engineering

    , M.Sc. Thesis Sharif University of Technology Rasti Boroojeni, Fatemeh (Author) ; Mashayekhan, Shohreh (Supervisor) ; Abbaszadeh, Hojjatollah (Supervisor) ; Hasannejad, Zahra (Co-Advisor)
    Abstract
    A system of electrospun scaffold containing drug-loaded chitosan nanoparticles was introduced for using in spinal cord tissue engineering. In spinal cord injury treatment, the formation of glial scar after injury which contains proteoglycans and activate glial cells should be avoided. In this study, the release of Dexamethasone sodium phosphate (DEXP) as a steroid anti-inflammatory agent from electrospun nanofiber composite containing chitosan nanoparticles was investigated. DEXP is believed to act through its glucocorticoid receptors found in most neurons and glial cells. These receptors’ pathways are involved in the inhibition of astrocyte proliferation and microglial activation.... 

    Image Reconstruction in Superconducting Bolometric Detector Infra Red Imaging System Based on Physical Optics Principle

    , M.Sc. Thesis Sharif University of Technology Aghaeizadeh Ghezelghaya, Mosa (Author) ; Fardmanesh, Mehdi (Supervisor) ; Kavehvash, Zahra (Co-Supervisor) ; Mirzaei, Eiman (Co-Supervisor)
    Abstract
    Recently Infrared imaging has been very much considered for its applications.and because the infrared wavelengths are harmless, considered in medical and industrial applications. the imaging system examined in this thesis is passive and the object's own radiation is received by a single-pixel detector, these images are taken by two superconducting sensors and a pyroelectric Sensor. the purpose of this thesis is to improve the quality of images And reconstruction for the resulting images and if possible, optimize the system. to improve this system, various work has been proposed and done. including parabolic mirror distortion survey available in the system and compensated for it, take a... 

    Theoretical Investigation of Hydrogen Bonding Effects on Interaction of Metal Nanoclusters with Biomolecules & Acidity Enhancement of Alcohols

    , Ph.D. Dissertation Sharif University of Technology Ali Akbar Tehrani, Zahra (Author) ; Fattahi, Alireza (Supervisor) ; Mahmoodi Hashemi, Mohammad (Supervisor) ; Jamshidi, Zahra (Co-Advisor)
    Abstract
    This thesis is divided into three parts: In part I, conformational properties of neutral, anionic, cationic and zwitterionic forms of glutathione tripeptide were investigated by means of DFT-B3LYP method with 6-31+G (d,p) basis set. Results show that glutathione is a very flexible molecule and its conformational energy landscape is strongly influenced by forming intramolecular hydrogen bond and its charge. Conformation of each amino acid in glutathione tripeptide depends on its orientation within the peptide sequence in addition to the conformation of other amino acids within the chain. Investigation of intramolecular hydrogen bonds in these conformers by means of AIM analysis demonstrates... 

    Constructing Calcite Core by Microbially Induced Calcite Precipitation (MICP) Usable in Oil and Gas Tests

    , M.Sc. Thesis Sharif University of Technology Ali Doust Salimi, Nazanin (Author) ; Yaghmaei, Soheila (Supervisor) ; Bazargan, Mohammad (Supervisor) ; Ghobadi Nejad, Zahra (Co-Supervisor)
    Abstract
    Acidizing is the most widely performed job to remove the formation damage, and enhance the oil recovery. Different models have been introduced to design the optimized condition for acidizing. However, none of them are able to predict the optimum injection flow rate in the actual application. As a result, Calcite cores are extracted from reservoirs for conducting experiments and modifying the present models. Nevertheless, acidizing is an intrusive technique destroying the costly extracted cores. Thus, there is a need to construct calcite cores of various porosities and permeabilities to take advantage of them in acidizing modelling.Microbially induced calcite precipitation is a well-known... 

    Investigation of The Effect Of Microgravity On Bone Marrow Stromal Cell Growth And Infiltration On An Optimized 3d Structured Scaffold

    , M.Sc. Thesis Sharif University of Technology Ahmadi, Armin (Author) ; Yaghmaei, Soheila (Supervisor) ; Vossoughi, Manouchehr (Supervisor) ; Haji Ebrahimi, Zahra (Supervisor) ; Janmaleki, Mohsen (Co-Supervisor)
    Abstract
    To develop a novel cell culture method for enhancement of bone marrow stromal cell growth and infiltration into the 3d electrospun PCL-based scaffold, we utilized the RPM system to simulate microgravity. In current study, six different scaffolds are produced using the electrospinningelectrospraying technique. These scaffolds are compared based on their structural (average diameter and SEM micrographs), mechanical (Tensile strength, elongation and wettability) and biological (Biodegradability, bioactivity, biocompatibility, cell adhesion, cell infiltration and antibacterial quality) characteristics. It is noted that the porous nano-hydroxyapatite/titanium hydroxide/polycaprolactone...