Sharif Digital Repository

This paper addresses a real-world problem faced by the public healthcare sector. The problem consists of both the patients’ and service provider's requirements (i.e., accessibility vs. costs) for locating healthcare facilities, allocating service units to those facilities, and determining the facilities’ capacities. The main contribution of this study is capturing both short-term and long-term uncertainties at the modelling stage. The queuing theory is incorporated to consider stochastic demand and service time as a short-term uncertainty, as well as a service level measurement. The developed nonlinear model is then converted into a linear model after introducing a new set of decision... 

Stochastic activity networks (SANs) are a well-known petri net-based formalism used for the performance and dependability modeling of a wide range of systems. On the other hand, the growing complexity of timed systems makes it imperative to apply formal analysis techniques in the early stages of the system's development. Finding a suitable framework for the modeling, evaluation, and verication of these systems is still a great challenge. In this paper, we introduce a new formalism named timed activity networks (TANs), which are based on the activity networks that are the nondeterministic settings of the SANs. The advantages of TANs are 2-fold: 1) allowing the construction of more compact... 

Real networks exhibit nontrivial topological features, such as heavy-tailed degree distribution, high clusteringsmall-worldness. Researchers have developed several generative models for synthesizing artificial networks that are structurally similar to real networks. An important research problem is to identify the generative model that best fits to a target network. In this paper, we investigate this problem and our goal is to select the model that is able to generate graphs similar to a given network instance. By the means of generating synthetic networks with seven outstanding generative models, we have utilized machine learning methods to develop a decision tree for model selection. Our... 

In this paper, we propose a two-phase approach to find the optimal solutions of a class of fuzzy linear programming problems called fully fuzzified linear programming (FFLP), where all decision parameters and variables are fuzzy numbers. Our approach is constructed on the basis of comparison of mean and standard deviation of fuzzy numbers. In this approach, the first phase maximizes the possibilistic mean value of fuzzy objective function and obtains a set of feasible solutions. The second phase minimizes the standard deviation of the original fuzzy objective function, by considering all basic feasible solutions obtained at the end of the first phase. The advantage of the proposed approach... 

Biomechanical modeling approaches require body posture to evaluate the risk of spine injury during manual material handling. The procedure to measure body posture via motion-analysis techniques as well as the subsequent calculations of lumbosacral moments and spine loads by, respectively, inverse-dynamic and musculoskeletal models are complex and time-consuming. We aim to develop easy-to-use yet accurate artificial neural networks (ANNs) that predict 3D whole-body posture (ANNposture), segmental orientations (ANNangle), and lumbosacral moments (ANNmoment) based on our measurements during load-handling activities. Fifteen individuals each performed 135 load-handling activities by reaching (0... 

Functional magnetic resonance imaging (fMRI) is an imaging tool that is used to analyze the brain’s functions. Brain functional connectivity analysis based on fMRI signals often calculated correlations among time series in different areas of the brain. For FC analysis most prior research works generate the brain graphs based on linear correlations, however, the nonlinear behavior of the brain can lower the accuracy of such graphs. Usually, the Pearson correlation coefficient is used which has limitations in revealing nonlinear relationships. One of the proper methods for nonlinear analysis is the Kernel trick. This method maps the data into a high dimensional space and calculates the linear... 

Alzheimer's Disease (AD) begins several years before the symptoms develop. It starts with Mild Cognitive Impairment (MCI) which can be separated into Early MCI and Late MCI (EMCI and LMCI). Functional connectivity analysis and classification are done among the different stages of illness with Functional Magnetic Resonance Imaging (fMRI). In this study, in addition to the four stages including healthy, EMCI, LMCI, and AD, the patients have been tracked for a year. Indeed, the classification has been done among 7 groups to analyze the functional connectivity changes in one year in different stages. After generating the functional connectivity graphs for eliminating the weak links, three... 

Purpose: Alzheimer's disease (AD) starts years before its signs and symptoms including the dementia become apparent. Diagnosis of the AD in the early stages is important to reduce the speed of brain decline. Aim of the study: Identifying the alterations in the functional connectivity of the brain during the disease stages is among the main important issues in this regard. Therefore, in this study, the changes in the functional connectivity during the AD stages were analyzed. Materials and methods: By employing the functional magnetic resonance imaging (fMRI) data and graph theory, weighted undirected graphs of the whole-brain and default mode network (DMN) network were investigated... 

Functional magnetic resonance imaging (fMRI) is a non-invasive method that helps to analyze brain function based on BOLD signal fluctuations. Functional Connectivity (FC) catches the transient relationship between various brain regions usually measured by correlation analysis. The elements of the correlation matrix are between -1 to 1. Some of them are very small values usually related to weak and spurious correlations due to noises and artifacts. They can not be concluded as real strong correlations between brain regions and their existence could make a misconception and leads to fake results. It is crucial to make a conclusion based on reliable and informative correlations. In order to... 

Functional magnetic resonance imaging (fMRI) is an imaging tool that is used to analyze the brain’s functions. Brain functional connectivity analysis based on fMRI signals often calculated correlations among time series in different areas of the brain. For FC analysis most prior research works generate the brain graphs based on linear correlations, however, the nonlinear behavior of the brain can lower the accuracy of such graphs. Usually, the Pearson correlation coefficient is used which has limitations in revealing nonlinear relationships. One of the proper methods for nonlinear analysis is the Kernel trick. This method maps the data into a high dimensional space and calculates the linear... 

Functional magnetic resonance imaging (fMRI) is a non-invasive method that helps to analyze brain function based on BOLD signal fluctuations. Functional Connectivity (FC) catches the transient relationship between various brain regions usually measured by correlation analysis. The elements of the correlation matrix are between -1 to 1. Some of them are very small values usually related to weak and spurious correlations due to noises and artifacts. They can not be concluded as real strong correlations between brain regions and their existence could make a misconception and leads to fake results. It is crucial to make a conclusion based on reliable and informative correlations. In order to... 

Functional magnetic resonance imaging (fMRI) is an imaging tool that is used to analyze the brain’s functions. Brain functional connectivity analysis based on fMRI signals often calculated correlations among time series in different areas of the brain. For FC analysis most prior research works generate the brain graphs based on linear correlations, however, the nonlinear behavior of the brain can lower the accuracy of such graphs. Usually, the Pearson correlation coefficient is used which has limitations in revealing nonlinear relationships. One of the proper methods for nonlinear analysis is the Kernel trick. This method maps the data into a high dimensional space and calculates the linear... 

Purpose: Alzheimer's disease (AD) starts years before its signs and symptoms including the dementia become apparent. Diagnosis of the AD in the early stages is important to reduce the speed of brain decline. Aim of the study: Identifying the alterations in the functional connectivity of the brain during the disease stages is among the main important issues in this regard. Therefore, in this study, the changes in the functional connectivity during the AD stages were analyzed. Materials and methods: By employing the functional magnetic resonance imaging (fMRI) data and graph theory, weighted undirected graphs of the whole-brain and default mode network (DMN) network were investigated... 

Effective connectivity is one of the most important considerations in brain functional mapping via EEG. It demonstrates the effects of a particular active brain region on others. In this paper, a new method is proposed which is based on dual Kalman filter. In this method, firstly by using a brain active localization method (standardized low resolution brain electromagnetic tomography) and applying it to EEG signal, active regions are extracted, and appropriate time model (multivariate autoregressive model) is fitted to extracted brain active sources for evaluating the activity and time dependence between sources. Then, dual Kalman filter is used to estimate model parameters or effective... 

Common similarity measures of time domain signals such as cross-correlation and Symbolic Aggregate approximation (SAX) are not appropriate for nonlinear signal analysis. This is because of the high sensitivity of nonlinear systems to initial points. Therefore, a similarity measure for nonlinear signal analysis must be invariant to initial points and quantify the similarity by considering the main dynamics of signals. The statistical behavior of local extrema (SBLE) method was previously proposed to address this problem. The SBLE similarity index uses quantized amplitudes of local extrema to quantify the dynamical similarity of signals by considering patterns of sequential local extrema. By... 

In this research, the interaction between electroencephalogram (EEG) and, a cardiac parameter, photoplethysmogram (PPG), using connectivity measures to emphasize the importance of autonomic nervous system over the central nervous system during a deception is investigated. In this survey, connectivity analysis was applied, since it can provide information flow of brain regions; moreover, lying and truth appear to be cohered with the flow of information in the brain. Initially, a new wavelet-based approach for EEG/PPG effective connectivity fusion was introduced; then, it was validated for 41 subjects. For each subject, after extracting specific wavelet component of EEG and PPG signals, an... 

Deception is mentioned as an expression or action which hides the truth and deception detection as a concept to uncover the truth. In this research, a connectivity analysis of Electro Encephalography study is presented regarding cognitive processes of an instructed liar/truth-teller about identity during an interview. In this survey, connectivity analysis is applied because it can provide unique information about brain activity patterns of lying and interaction among brain regions. The novelty of this paper lies in applying an open-ended questions interview protocol during EEG recording. We recruited 40 healthy participants to record EEG signal during the interview. For each subject,...