Sharif Digital Repository

Major bone defects resulted from diseases or hurts that can not heal naturally, requaire bone transplantation. golden standard for transplantation is autologus one but it has some disad-vantages such as economic burden, the lack of graft source, surgery on patient, and so on. so exploring altrnative ways led to exploit stem cells.traditionally bone marrow mesenchymal stem cells (MSCs) used for stem cell-bsaed bone regeneration. bone marrow aspiration to aquaire stem cells is painfull and give a population of cells such as hematopoetic cells that requaire to seperate and can not be handled in first passages. MSCs can be substituted by multipotent adipose tissue-derived stem cells (ADSCs) in... 

Social enterprises are organisations comprised of two conflicting logics: social and commercial. However, simultaneous commitment to both logics often leads to tensions, making social enterprises fragile organisations at the risk of mission drift. The extant literature on hybridity highlights two important overall strategies – integration and differentiation - for managing tensions. However, integration or differentiation alone can create additional problems, which is especially true in the case of differentiation, creating a situation comparable to black and white, with a salient faultline and heated conflicts. In this inductive qualitative case study, responding to the recent call in the...