Sharif Digital Repository

Sulfur containing compounds are known as the most applicable group of organic compounds. Due to their medicinal and biological applications, dithiocarbamates are the most considerable among the many sulfur containing compounds. There are many procedures reported to synthesize these compounds as synthetic intermediates instead of thiophosgen and isothiocyanates. The reaction of amine and carbon disulfide is reported as the best and least hazardous way to synthesize this functional group. In this project heterocyclic compounds such as thiazoles, thiazolidine-2-thione, and 2-(alkylthio)thiazol-4(5H)-one derivatives were synthesized from the reaction of prepared dithiocarbamates with in situ... 

Considering the advantages of heterogeneous catalysts for the easy work up procedure, being eco-friendly, and the reusability, herein, two projects are carried out by metal-supported SBA-15 catalysts. The first one is the oxidative deprotection of trimethylsilyl ethers catalyzed Cr (VI) in the presence of TBHP as oxidant. In this project, trimethylsylil ethers are oxidized in good to high yields. The second project is the oxidative coupling of thiols to disulfides catalyzed by Fe (III) in the presence of hydrogenperoxide. This catalyst/oxidant system convets different aromatic thiols to corresponding disulfides efficiently  

The reaction of α-haloketones with a variety of dithiocarbamate derivatives for the synthesis of various 2-alkylthiothiazole heterocyclic compounds was investigated in this thesis. To this end, different dithiocarbamates were initially synthesized through the reaction of amines, carbon disulfide and various alkyl halides; then, these dithiocarbamates were reacted with α-bromoketones (bromoacetophenone and chloroacetone) resulting in the formation of range of 2-alkyl thiothiazoles. To optimize the reaction conditions, ethanol and water were tested as solvents in the presence of ZrCl4 as catalyst. According to the data obtained, ethanol was selected as the optimum solvent using ZrCl4 as... 

This research project contains two parts that investigating new approaches for becoming closer to green chemistry principals is clear in it. In the first part we tried to synthesis dithiocarbamate salts using aromatic amins and than Michael addition of them to prepare bifunctional dithiocarbamats. But we found ?-thiols as final product. In the second part of this project, we investigated the regioselective epoxide ring opening with aromatic amines by using boric acid and glycerol in water as a green media. Corresponding ?-amino alcohols were obtained with excellent yields and considerable regioselectivity. High yields of the products, mild reaction conditions, using green catalyst and water... 

Dithiocabamates are valuable compounds due to their wide application as herbicides, fungicides, antitumor and etc. Another aspect of dithiocarbamates is their application in coordination chemistry. In this project, 3-((pyridin-2-yl) methyl amino) propane nitrile was prepared via Michael addition reaction of 1-methyl¬amino¬pyridine and acrylonitrile in water. Then this compound was converted to its potassium dithiocarbamate salt via treatment with carbon disulfide in the presence of potassium hydroxide in tetrahydrofuran. The prepared ligand was used in complexation with metal salts of Zn, Hg, Ni and Sn to prepare their dithiocarbamate complexes. The structure of complexes was elucidated by... 

This projct includes the following sections: In the first section, Michael addition reaction of anthrone to nitroolefins is described in water without using any catalyst to prepare 9-(2-nitro-1-arylethyl)anthracene-10(9H)-ones. This method is green, efficient and gives high yields of products. The solvent effect is also investigated. In the second section, Considerable efforts have been directed in recent years towards the transition metal complex catalyzed oxidation of organic compounds such as olefins, sulfides, benzylics alcohols and phenolics. And due to the various advantages of supported heterogeneous catalysts and in our aim to develop a simple, more efficient and eco-friendly...