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    Formaldehyde biodegradation using an immobilized bed aerobic bioreactor with pumice stone as a support

    , Article Scientia Iranica ; Volume 18, Issue 6 , December , 2011 , Pages 1372-1376 ; 10263098 (ISSN) Ebrahimi, S ; Borghei, M ; Sharif University of Technology
    Abstract
    The objective of this study is the investigation of formaldehyde degradation in a bioreactor with pumice stone as a support. The reactor was tested at different synthetic wastewater concentrations with total COD of 500, 1000 and 1500 mgL, respectively, at 24 h hydraulic retention time. The effect of feed composition was tested by changing the COD TCOD FA ratio in order to analyze the impact of formaldehyde concentration. The average formaldehyde and COD removal efficiencies obtained in the reactor were 97.1% and 88%, respectively. The maximum COD and formaldehyde removal efficiencies occurred at the COD TCOD F of 41 at COD T=1000mgL. The effect of toxic shock on reactor performance was... 

    Heavy metal tolerance of fungi

    , Article Scientia Iranica ; Volume 18, Issue 3 C , 2011 , Pages 502-508 ; 10263098 (ISSN) Anahid, S ; Yaghmaei, S ; Ghobadinejad, Z ; Sharif University of Technology
    Abstract
    This study was focused on the heavy metal (Ni, Co, Mo, V, Mn, Fe, W and Zn) tolerance of fungi strains Aspergillus niger, Aspergillus foetidus and Penicillium simplicissimum. Aspergillus niger was exposed to a mixture of Mo, V and Mn at a mass ratio of 1:2:6 as approximately present in the spent refinery processing catalyst. This study highlights the adaptation of fungi strains to Tungsten and Vanadium to high concentration. The effect of different metals and metal concentration on different strains of fungi was evaluated. Results showed that Ni was one of the most toxic metals for strains of Aspergillus and Penicillium. Aspergillus foetidus was the least tolerant, in particular for Ni, Co... 

    Removal of chlorophenolic derivatives by soil isolated ascomycete of Paraconiothyrium variabile and studying the role of its extracellular laccase

    , Article Journal of Hazardous Materials ; Volume 209-210 , 2012 , Pages 199-203 ; 03043894 (ISSN) Forootanfar, H ; Movahednia, M. M ; Yaghmaei, S ; Tabatabaei Sameni, M ; Rastegar, H ; Sadighi, A ; Faramarzi, M. A ; Sharif University of Technology
    2012
    Abstract
    The ability of Paraconiothyrium variabile, a laccase producing ascomycete recently isolated from soil, was studied to eliminate chlorophenol derivatives in submerged culture medium. Among the tested compounds, ρ-chlorophenol (ρ-CP) and pentachlorophenol (PCP) were found to have minimum and maximum toxic effects, respectively, on the growth of the microorganism and at the same time high and low bioelimination percentages. The fungal strain was able to remove 86% of ρ-CP (with initial concentration of 40mgl -1) and 56% of 2,4-dichlorophenol (2,4-DCP; with same concentration as ρ-CP) after 9 days of incubation while no elimination was observed in the presence of 2,4,6-trichlorophenol... 

    A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles

    , Article Colloids and Surfaces B: Biointerfaces ; Volume 75, Issue 1 , 2010 , Pages 300-309 ; 09277765 (ISSN) Mahmoudi, M ; Simchi, A ; Imani, M ; Shokrgozar, M. A ; Milani, A. S ; Häfeli, U. O ; Stroeve, P ; Sharif University of Technology
    Abstract
    Superparamagnetic iron oxide nanoparticles (SPIONs) are increasingly used in medical applications, such as targeting delivery and imaging. In the future, patients are more likely to be exposed to pharmaceutical products containing such particles. The study of toxicity of SPIONs has become of great importance in recent years, although the published data in this arena is limited. The aim of the present work is to investigate the cytotoxicity of SPIONs and the effect of the particles on the cell medium components. For this purpose, uncoated and polyvinyl alcohol (PVA) coated SPIONs with narrow size distribution were synthesized via a well-known coprecipitation method. The mouse fibroblast cell... 

    Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy

    , Article Advanced Drug Delivery Reviews ; Volume 63, Issue 1-2 , January–February , 2011 , Pages 24-46 ; 0169409X (ISSN) Mahmoudi, M ; Sant, S ; Wang, B ; Laurent, S ; Sen, T ; Sharif University of Technology
    2011
    Abstract
    At present, nanoparticles are used for various biomedical applications where they facilitate laboratory diagnostics and therapeutics. More specifically for drug delivery purposes, the use of nanoparticles is attracting increasing attention due to their unique capabilities and their negligible side effects not only in cancer therapy but also in the treatment of other ailments. Among all types of nanoparticles, biocompatible superparamagnetic iron oxide nanoparticles (SPIONs) with proper surface architecture and conjugated targeting ligands/proteins have attracted a great deal of attention for drug delivery applications. This review covers recent advances in the development of SPIONs together...