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Experimental design in analytical chemistry -Part I: Theory

Ebrahimi-Najafabadi, H ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.5740/jaoacint.SGEEbrahimi1
  3. Abstract:
  4. This paper reviews the main concepts of experimental design applicable to the optimization of analytical chemistry techniques. The critical steps and tools for screening, including Plackett-Burman, factorial and fractional factorial designs, and response surface methodology such as central composite, Box-Behnken, and Doehlert designs, are discussed. Some useful routines are also presented for performing the procedures
  5. Keywords:
  6. Box-behnken ; Central composite ; Critical steps ; Doehlert design ; Fractional factorial designs ; Plackett-burman ; Response surface methodology ; Agronomy ; Statistics ; Algorithm ; Chemical analysis ; Methodology ; Review ; Theoretical model ; Algorithms ; Chemistry techniques, analytical ; Models, theoretical ; Research design
  7. Source: Journal of AOAC International ; Vol. 97, issue. 1 , 2014 , pp. 3-11 ; ISSN: 10603271
  8. URL: http://www.ingentaconnect.com/content/aoac/jaoac/2014/00000097/00000001/art00002