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Modeling of self-controlling hyperthermia based on nickel alloy ferrofluids: Proposition of new nanoparticles

Delavari H. H ; Sharif University of Technology | 2013

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  1. Type of Document: Article
  2. DOI: 10.1016/j.jmmm.2013.01.027
  3. Publisher: 2013
  4. Abstract:
  5. In order to provide sufficient heat without overheating healthy tissue in magnetic fluid hyperthermia (MFH), a careful design of the magnetic properties of nanoparticles is essential. We perform a systematic calculation of magnetic properties of Ni-alloy nanoparticles. Stoner-Wohlfarth model based theories (SWMBTs) are considered and the linear response theory (LRT) is used to extract the hysteresis loop of nickel alloy nanoparticles in alternating magnetic fields. It is demonstrated that in the safe range of magnetic field intensity and frequency the LRT cannot be used for the calculation of the area in the hysteresis for magnetic fields relevant for hyperthermia. The best composition and particle size for self-controlling hyperthermia with nickel alloys is determined based on SWMBTs. It is concluded that Ni-V and Ni-Zn are good candidates for self-controlling hyperthermia
  6. Keywords:
  7. Hyperthermia ; Modeling ; Nanoparticle ; Nickel alloy ; Alternating magnetic field ; Linear-response theory ; Magnetic fluid hyperthermia ; Magnetic properties of nanoparticle ; Magnetic-field intensity ; Self-controlling ; Stoner-Wohlfarth model ; Magnetic fields ; Magnetic fluids ; Magnetic properties ; Models ; Nickel ; Nickel alloys ; Tissue ; Nanoparticles
  8. Source: Journal of Magnetism and Magnetic Materials ; Volume 335 , 2013 , Pages 59-63 ; 03048853 (ISSN)
  9. URL: http://www.sciencedirect.com/science/article/pii/S0304885313000413