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One-pot reductive amination of aldehydes by the dihydropyridine in water

Ghafuri, H ; Sharif University of Technology | 2012

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  1. Type of Document: Article
  2. DOI: 10.1016/j.scient.2012.10.030
  3. Publisher: 2012
  4. Abstract:
  5. An efficient, highly chemoselective and simple synthesis of secondary amines via reductive amination of aldehydes, aromatic amines and inexpensive and easily accessible Diethyl 2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate (DHP) in the presence of catalytic amounts of p-toluenesulfonic acid (PTSA) in water in good to excellent yields is reported
  6. Keywords:
  7. Dihydropyridine ; Aromatic amines ; Catalytic amounts ; Chemoselective ; Dihydropyridines ; One pot ; p-Toluene sulfonic acids ; Reductive amination ; Secondary amines ; Aldehydes ; Pyridine ; Amines ; Aldehyde ; Catalyst ; Chemosynthesis ; Reduction ; Water chemistry
  8. Source: Scientia Iranica ; Volume 19, Issue 6 , December , 2012 , Pages 1591-1593 ; 10263098 (ISSN)
  9. URL: http://www.sciencedirect.com/science/article/pii/S1026309812002416