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Autoregressive modeling of the photoplethysmogram AC signal amplitude changes after flow-mediated dilation in healthy and diabetic subjects

Amiri, M ; Sharif University of Technology | 2012

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  1. Type of Document: Article
  2. DOI: 10.1109/ICBME.2012.6519679
  3. Publisher: 2012
  4. Abstract:
  5. It is proved that the endothelial (artery inner lumen cells) function is associated with cardiovascular risk factors. Among all the common non-invasive methods employed in the research setting for assessing endothelial function, flow-mediated dilation is the most widely used one. This technique measures endothelial function by inducing reactive hyperemia using temporary arterial occlusion and measuring the resultant relative increase in blood vessel diameter via ultrasound. In this paper, the limitations associated with the ultrasound technique are overcome by using the photoplethysmogram (PPG) signal recorded during FMD. The correctness of this approach is investigated by modeling the AC changes of PPG after FMD by a 2nd order autoregressive model. A sensitivity of 78.6%, specificity of 81.6% and total accuracy of 80% were achieved in classification of 16 healthy and 14 diabetic subjects
  6. Keywords:
  7. AR modeling ; Diabetes ; Auto regressive models ; Autoregressive modeling ; Blood vessel diameter ; Cardio-vascular risk factors ; Endothelial function ; FMD ; PPG ; Ultrasound techniques ; Biomedical engineering ; Blood vessels ; Medical problems ; Noninvasive medical procedures ; Ultrasonic applications ; Ultrasonics ; Endothelial cells
  8. Source: 2012 19th Iranian Conference of Biomedical Engineering, ICBME 2012 ; 2012 , Pages 170-173 ; 9781467331302 (ISBN)
  9. URL: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6519679