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CuO nanoparticles: A mild and efficient reusable catalyst for the one-pot synthesis of 4-amino-5-pyrimidinecarbonitriles under aqueous conditions

Ahmadi, S. J ; Sharif University of Technology | 2012

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  1. Type of Document: Article
  2. DOI: 10.4028/www.scientific.net/DDF.326-328.372
  3. Publisher: 2012
  4. Abstract:
  5. An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by three-component reaction of malononitrile, aldehydes and N-unsubstituted amidines, under aqueous conditions, using CuO nanoparticles as catalyst is reported. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst
  6. Keywords:
  7. 4-amino-5-pyrimidinecarbonitrile ; CuO nanoparticles ; Supercritical water synthesis ; Aqueous condition ; Higher yield ; Malononitriles ; Mild reaction conditions ; One-pot synthesis ; Reusable catalysts ; Short reaction time ; Supercritical water ; Three component reactions ; Aldehydes ; Catalysts ; Diffusion in solids ; Heat transfer ; Liquids ; Mass transfer ; Microstructure ; Nanostructured materials ; Reusability ; Synthesis (chemical)
  8. Source: Defect and Diffusion Forum ; Volume 326-328 , 2012 , Pages 372-376 ; 10120386 (ISSN) ; 9783037854006 (ISBN)
  9. URL: http://www.scientific.net/DDF.326-328.372