Study on the Efficiency of Graphene and Graphene Oxide-coated Iron Oxide Nanoparticles in the Treatment of Cancer Cells to Hyperthermia

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Azizi Darsara, Fatemeh | 2015

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Type of Document: M.Sc. Thesis
Language: Farsi
Document No: 47886 (46)
University: Sharif University of Technology
Department: Energy Engineering
Advisor(s): Otukesh, Mohammad; Saligheh Rad, Hamid Reza
Abstract:
The main methods have been used clinically for cancer treatment are included: surgery, chemotherapy, radiation therapy and hyperthermia. Hyperthermia (heat therapy) treatment method in which by raising the temperature of the tumor it removed. Magnetic hyperthermia is known as a kind of hyperthermia that have been represent appropriate results. In this study, using iron oxide nanoparticle coated with graphene for cancer treatment under a magnetic field of the laser. In the first stage, graphene oxide nanosheets and nanoparticles Magntayt are synthesized by chemical oxidation and co-precipitation, respectively. At the end, the nanoparticles on the substrate of graphene layer is obtained nanostructured magnetic properties. Characterization tests such as AFM, XPS, VSM, UV, TEM, XRD, RAMAN measure thermal, magnetic and optical properities of nanoparticles. The results of these tests show superparamagnetic nanoparticle Magntayt. The main result of this study shows nanomaterial be useful for cancer treatment in hyperthermia-laser test with low power laser
Keywords:
Graphene Oxide ; Superparamagnetic Nanoparticles ; Hyperthermia Treatment ; Cancer Treatment ; Iron Oxide Nanoparticles ; Hyperthermia Magnetic Particles ; Laser Hyperthermia

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