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Dithiocarbamate as an efficient intermediate for the synthesis of 2-amino-1,3,4-thiadiazoles in water
Aryanasab, F ; Sharif University of Technology | 2010
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- Type of Document: Article
- DOI: 10.1016/j.tetlet.2009.11.100
- Publisher: 2010
- Abstract:
- A new and facile protocol for the synthesis of 2-amino-1,3,4-thiadiazoles in water is described. Reaction of acid hydrazides with easily prepared dithiocarbamates gives the corresponding thiadiazoles in moderate to excellent yields. 2-Amino-1,3,4-oxadiazoles were not observed as side products using this procedure
- Keywords:
- Aminothiadiazole ; Dithiocarbamic acid ; Hydrazide ; Thiadiazole derivative ; Water ; Chemical reaction ; One pot synthesis
- Source: Tetrahedron Letters ; Volume 51, Issue 5 , February , 2010 , Pages 790-792 ; 00404039 (ISSN)
- URL: http://www.sciencedirect.com/science/article/pii/S0040403909022205