Simulation of Droplet Sorting in Microfluidic Systems

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Fattahi, Hamid Reza | 2017

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Type of Document: M.Sc. Thesis
Language: English
Document No: 49711 (58)
University: Sharif University of Technology, International Campus, Kish Island
Department: Science and Engineering
Advisor(s): Mousavi, Ali; Asghari, Mohsen
Abstract:
A new microfluidic device is introduced for sorting the particles based on the hydrodynamic resistance induced in a microchannel which is not needed for additional detection or sorting modules. Hydrodynamic resistance affects physical properties, such as size and deformability of the particle. This device could apply application in cell sorting for remedies, diagnostics, and industrial applications. The device design is performed using an equivalent resistance model, and also numerical simulations are performed. For validation of the results, they are compared with experimental results. Moreover, we will discuss threshold particle size and will introduce a way to approximate it to obtain it quickly. Consequently, the primary simple device will be developed to an advanced system to sort any desired range size of particles incessantly
Keywords:
Sorting ; Simulation ; Microfluidic System ; Separation ; Droplet Formation Hydrodynamics ; Drop Shape

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