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The use of optical coherence tomography to analyze the efficacy of skin care products

Irani, S ; Sharif University of Technology | 2018

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  1. Type of Document: Article
  2. DOI: 10.1117/12.2291404
  3. Publisher: SPIE , 2018
  4. Abstract:
  5. Background: Optical coherence tomography (OCT) is an imaging method that provides real time in situ visualization of human tissue at sub-micrometer resolution. Prior research shows OCT is suitable for imaging the epidermis. Method: In this study, we utilized OCT images to noninvasively measure the quantitative effect of a specialized antiaging product compared with a petrolatum control in a split-face trial. The images acquired with OCT were analyzed to determine the average surface roughness, Ra, and surface roughness depth, Rz, of the imaged skin. These values were measured over the duration of a 28-day trial. Results: The petrolatum treated skin showed a 2.1% and 2.9% decrease in Ra and Rz values after four weeks, respectively, while the antiaging product treated skin showed a 5.9% and 6.5% decrease in Ra and Rz, respectively. Paired sample t-tests were performed and it was determined the changes in skin roughness were statistically significant. Conclusion: We conclude that the antiaging cream indeed does have a greater positive impact on skin roughness than the petrolatum product. In addition to demonstrating the benefits of the antiaging product, our study demonstrates the utility of OCT imaging as a noninvasive method of measuring the effect of skin care products. Copyright © 2018 SPIE
  6. Keywords:
  7. Dermatology ; OCT ; Optical coherence tomography ; Skin roughness ; Noninvasive medical procedures ; Optical tomography ; Surface roughness ; Surgery ; Antiaging products ; Average surface roughness ; Noninvasive methods ; Paired-sample t-test ; Quantitative effects ; Situ visualization ; Submicrometer resolution ; Wrinkle reduction ; Skin care products
  8. Source: Photonics in Dermatology and Plastic Surgery 2018, 27 January 2018 through 28 January 2018 ; Volume 10467 , 2018 ; 16057422 (ISSN); 9781510614192 (ISBN)
  9. URL: https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10467/1046715/The-use-of-optical-coherence-tomography-to-analyze-the-efficacy/10.1117/12.2291404.short?SSO=1