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A simple, economical, and highly efficient synthesis of β-hydroxynitriles from epoxide under solvent free conditions

Mirmashhori, B ; Sharif University of Technology | 2006

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  1. Type of Document: Article
  2. DOI: 10.1016/j.molcata.2005.11.042
  3. Publisher: 2006
  4. Abstract:
  5. A simple, rapid, and highly regioselective green protocols for the synthesis of β-hydroxylnitriles by the direct reaction of epoxides with trimethylsilyl cyanide in the presence of catalytic amount of lithium perchlorate under solvent free conditions in high to quantitative yield is reported. © 2005 Elsevier B.V. All rights reserved
  6. Keywords:
  7. Cyanides ; Lithium compounds ; Lithium perchlorate ; Regioselective ; Trimethylsilyl cyanide ; Nitrogen compounds
  8. Source: Journal of Molecular Catalysis A: Chemical ; Volume 247, Issue 1-2 , 2006 , Pages 159-161 ; 13811169 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/pii/S138111690500806X