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Investigation of Designing and Material Property Parameters in Mechanical Behavior of Balloonexpandable Stent in Coronary Artery by Finite Element Analysis

Yousefan, Mohammad Mahdi | 2021

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 54541 (08)
  4. University: Sharif University of Technology
  5. Department: Mechanical Engineering
  6. Advisor(s): Arghavani Hadi, Jamal
  7. Abstract:
  8. The coronary arteries of the heart are one of the most important arteries in the body's cardiovascular system, which carry oxygen and nutrients to the heart.Therefore, coronary heart disease is one of the most important causes of death in society. In this disease, when the adhesion of sediments and blood plugs to the walls of the arteries increase, the ducts become narrow and the circulatory system gets hard. As a result, the risk of heart attack and mortality increases.Due to the increase in mortality caused by coronary heart disease, working on treatment methods for this disease is important. Angioplasty and stent implantation in a vein are the latest treatments for this disease and have become a good alternative to open-heart surgery. It has been almost three decades since the first cardiac stent was implanted, but there is a great deal of experimental and clinical evidence that, in some cases, the vessel becomes narrow again after the stent is implanted. To solve this problem, a lot of research has been done to provide an optimal and body-compatible design, and stents have been marketed with different structures and raw materials. So, the material and geometric shape of the stent and its implantation technique have a significant effect on the performance of the stent and the vein may become narrower.In the product development process, the use of numerical solution methods to solve complex physical problems is always superior to the product manufacturing process. In simulating the performance of a loaded stent, the finite element method is one of the best and most accurate methods available for evaluating stent performance. Because this method reduces the risk of conducting experimental tests and the cost of making the sample.In this study, changes in stent geometry design parameters, as well as material parameters on the performance of the balloon expanding stent, were investigated. The results show that the effect of geometric parameters on material stent expansion is much greater than material parameters. Changes in the thickness or metal to artery ratio have the greatest impact on the results. On the other hands, by reducing the properties of the plastic, the results will be closer to the ideal stent. Finally, by using product optimization, an optimal design for the expandable balloon stent was proposed. Also, the method of conducting this research can be a basis for the development of expandable stents in the future
  9. Keywords:
  10. Coronary Artery ; Finite Element Method ; Coronary Stent ; Angiography ; Laser Cutting ; Balloon Expandable Stent ; Geometric Parameters

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