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Experimental investigation and finite element modelling of PMMA/carbon nanotube nanobiocomposites for bone cement applications

Sadati, V ; Sharif University of Technology | 2022

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  1. Type of Document: Article
  2. DOI: 10.1039/d2sm00637e
  3. Publisher: Royal Society of Chemistry , 2022
  4. Abstract:
  5. Multi-walled carbon nanotubes (MWCNTs) are one of the preferred candidates for reinforcing polymeric nanobiocomposites, such as acrylic bone type of cement. In this study, at first, bulk samples of the reinforced polymethylmethacrylate (PMMA) matrix were prepared with 0.1, 0.25, and 0.5 wt per wt% of MWCNTs by the casting method. Tensile and three-point bending tests were performed to determine the essential mechanical properties of bone cement, such as tensile and bending strengths. The tensile fracture surfaces were investigated by scanning electron microscopy (SEM). The commercial software (Abaqus) was used to conduct finite element analysis (FEA) by constructing a representative volume element (RVE) model for numerically computing the tensile and bending parameters of PMMA-MWCNT nanocomposites. Finally, MTT assays were utilized to evaluate the cell viability on the surface of nanobiocomposites. The results show that by increasing the MWCNT amount in the PMMA-based cement, the bending strengths (BS), tensile strength (TS), and elastic modulus (EM) increased considerably. Furthermore, the disparity between the FEA and experimental TS, EM, and BS values was less than 20%. According to MTT viability experiments, adding MWCNTs to PMMA had no influence on PMMA toxicity and resulted in a negative response to interaction with mesenchymal stem cells. The cell density on the nanobiocomposite was more than pristine-PMMA. © 2022 The Royal Society of Chemistry
  6. Keywords:
  7. ABAQUS ; Bending tests ; Biomechanics ; Bone ; Bone cement ; Cell culture ; Finite element method ; Multiwalled carbon nanotubes (MWCN) ; Scanning electron microscopy ; Stem cells ; Tensile strength ; Bulk samples ; Casting method ; Element models ; Experimental investigations ; Finite element analyse ; Matrix ; Multi-walled-carbon-nanotubes ; Nano-biocomposites ; Tensile fracture surfaces ; Three-point bending test ; Bending strength ; Carbon nanotube ; Poly(methyl methacrylate) ; Finite element analysis ; Materials testing ; Bone Cements ; Nanotubes, Carbon ; Polymethyl Methacrylate
  8. Source: Soft Matter ; Volume 18, Issue 36 , 2022 , Pages 6800-6811 ; 1744683X (ISSN)
  9. URL: https://pubs.rsc.org/en/content/articlelanding/2022/sm/d2sm00637e