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Design of the Coronary Stent Device to Improve Fluid Flow in Coagulated Vascular Regions

Haghayegh Jahromi, Mohammad | 2015

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  1. Type of Document: M.Sc. Thesis
  2. Language: English
  3. Document No: 47678 (58)
  4. University: Sharif University of Technology, International Campus, Kish Island
  5. Department: Science and Engineering
  6. Advisor(s): Shamloo, Amir
  7. Abstract:
  8. The application of computational fluid dynamics (CFD) has been growing rapidly in biomedical engineering. The altered hemodynamics inside the blood vessels plays a key role in the development of the arterial disease called atherosclerosis, which is the major cause of human death worldwide. Atherosclerosis is often treated with the stenting procedure to restore the normal blood flow. A stent is a tubular, flexible structure, usually made of metals, which is driven and expanded in the blocked arteries. The presence of non-biological device in the artery causes inflammation or re-growth of atherosclerotic lesions in the treated vessels. Several factors including the design of stents and type of stent expansion influence the restenosis process. Here, hemodynamic of blood is investigated in the presence of a coronary stent to examine the effects of blood dynamics and the resulting stresses on the vessel walls. Furthermore, the strut thickness, and flat edge of strut has been changed to investigated the effect of this parameter on the blood flow and study this parameter on the region of created vortex. It conclude that non streamlined stent struts geometries such as rectangular cross-sectional geometries can reach higher levels of WSS in comparison to streamlined geometries
  9. Keywords:
  10. ARTERY STENOSIS ; Stress ; Computational Fluid Dynamics (CFD) ; Hemodynamics ; Coronary Stent ; Optimal Geometry

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