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Straightforward and highly efficient catalyst-free one-pot synthesis of dithiocarbamates under solvent-free conditions
Azizi, N ; Sharif University of Technology | 2006
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- Type of Document: Article
- DOI: 10.1021/ol0620141
- Publisher: 2006
- Abstract:
- A highly efficient and simple synthesis of dithiocarbamates is possible based on the one-pot reaction of amines, CS2, and alkyl halides without using a catalyst under solvent-free conditions. The mild reaction conditions, high yields, and broad scope of the reaction illustrate the good synthetic utility of this method. The reaction is a highly atom-economic process for production of S-alkyl thiocarbamates and successfully can be used in high quantities in the pharmaceutical or agrochemical industries. © 2006 American Chemical Society
- Keywords:
- Thiocarbamic acid derivative ; Catalysis ; Chemical structure ; Synthesis ; Catalysis ; Molecular Structure ; Thiocarbamates
- Source: Organic Letters ; Volume 8, Issue 23 , 2006 , Pages 5275-5277 ; 15237060 (ISSN)
- URL: https://pubs.acs.org/doi/10.1021/ol0620141