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4-amino-5-pyrimidinecarbonitrile
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CuO nanoparticles: A mild and efficient reusable catalyst for the one-pot synthesis of 4-amino-5-pyrimidinecarbonitriles under aqueous conditions
, Article Defect and Diffusion Forum ; Volume 326-328 , 2012 , Pages 372-376 ; 10120386 (ISSN) ; 9783037854006 (ISBN) ; Sadjadi, S ; Hosseinpour, M ; Sharif University of Technology
2012
Abstract
An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by three-component reaction of malononitrile, aldehydes and N-unsubstituted amidines, under aqueous conditions, using CuO nanoparticles as catalyst is reported. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst
Granulated copper oxide nanocatalyst: A mild and efficient reusable catalyst for the one-pot synthesis of 4-amino-5-pyrimidinecarbonitriles under aqueous conditions
, Article Monatshefte fur Chemie ; Volume 142, Issue 11 , November , 2011 , Pages 1163-1168 ; 00269247 (ISSN) ; Sadjadi, S ; Hosseinpour, M ; Sharif University of Technology
2011
Abstract
An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by the three-component reaction of malononitrile, aldehydes, and N-unsubstituted amidines under aqueous conditions using CuO microspheres as catalyst is reported. The catalyst exhibited remarkable reusable activity. Graphical abstract: [Figure not available: see fulltext.]