Sharif Digital Repository

More than 80% of desalination units in the Persian Gulf use multi-stage flash (MSF) technology. The discharge of effluent from these units sometimes causes severe impacts to the marine environment due to the increase in temperature and salinity around the discharge point. In the current thesis, the geometrical, mixing and turbulence characteristics of the discharge of thermal-saline inclined jets under the water surface, similar to the effluent of MSF units, are numerically investigated by developing the buoyantBoussinesqPimpleFoam solver in the OpenFoam open-source software, using the LES turbulence model and the dynamic Smagorinsky subgrid scale and the UNESCO equation of state. The... 

In this study, DREAM model operation as a model to predict the occurrence of dust storms has been completed. The aim of this study is to identify capability of the model to predict dust storms in IRAN. The model has been run for June 2014 because on 2 June 2014, Tehran visited a dust storm with a speed of 111 kilometers per hour and yielded a huge economic losse. In this model, dust concentration,dust load and Aerosol Optical Depth(AOD) are calculated on an hourly basis. The model results do not captured the direct relationship between the average wind speed and dust Parameters and the model do not predict the dust storm on on 2 June 2014 in Tehran. The reason is that DREAM gets... 

Bubble formation and bubble rising are widely used in many industrial processes such as bubble columns, extraction, fermentation, foaming and polymerization. Although many of these processes are faced with a series of bubbles, this study may help us better understand the hydrodynamics of single bubble formation and bubble rising and provides a deep insight into the modeling of a series of bubbles. Bubble velocity and drag coefficient in various fluids are the major parameters for designing the liquid-gas systems. These parameters are a function of the bubble size. In this study, single bubble formation is theoretically modelled in order to predict the size of the bubble at the moment of... 

Endothelial cells that cover the inner wall of blood cells and are sensitive to receiving mechanical signals play important role in regulating many vital activities of the human body especially the function of the cardiovascular system. One of the factors affecting the mechanical functions of these cells is the shear stress applied to them. Due to blood velocity increasing or decreasing the endothelial cells shear stress change and leads to some chemical reactions and finally releasing biochemical substances including Nitrogen-Monoxide and Calcium-ion. Nitrogen-Monoxide produced by endothelial cells by affecting the smooth muscle cells in the vessel wall causes dilating of the vessel wall,... 

This thesis introduces a fast and accurate two-phase reservoir flow simulation procedure. The speed up is achieved by an upscaling technique where coarsening is applied to the detailed geological reservoir descriptions. This process results to two major error sources affecting the simulation accuracy significantly. The homogenization error is appeared when coarse scale data, such as equivalent permeability, is calculated from the available fine grid model information. It is shown that the error can be reduced adjusting coarse grid (non-uniform Cartesian) distribution. For the first time in this study, the grid distribution optimization is done based on “vorticity” map. In particular, the... 

Sedimentation tanks are channels designed for sedimentation of suspended solids in water. These tanks are one of the most important parts of water treatment plants and their performance directly affects the functionality of water treatment plants. Therefore, researchers have tried to find better designs of sedimentation tanks. Among several design methods have been presented, modification of the geometry of tanks by installing baffles is one of the most effective and economic methods. According to the importance of performance improvement of industrial sedimentation tanks as well as the diversity in reported results, development and completion of previous studies seem to be necessary. In... 

Blood clotting and clot formation in damaged vessels are vital mechanisms of the body. Any disorder in performing this mechanism leads to various problems such as excessive bleeding or, on the contrary, causes vascular occlusion and diseases such as embolism. Due to the importance of this issue, extensive research has been done to understand this phenomenon and the factors affecting it. In this thesis, the effect of shear stress, coagulation factor concentration and wound location in coronary bifurcation on clot formation and growth and its interaction with velocity field is numerically investigated. Blood flow is modeled non-Newtonian with Carreau-Yasuda model. Various chemical species... 

Dense underflows are continuous currents that move down-slope due to their density being heavier than that of the ambient water. This difference between the dense fluid and environment fluid can be due to temperature difference, chemical materials, solved materials or suspend solid particles. In these currents, the effect of buoyancy force is produced by this difference density. In this research, many experiments performed in different flow rates, slopes and concentrations to understand the current structure and turbulence specification of the salt solution density currents and particle-laden density currents. Acoustic Doppler Velocimeter is used to measure the velocity fluctuations. The... 

In this thesis, hemodynamic parameters of flow and deposition of low density lipoproteins (LDL) on wall of coronary arteries with taking into account their curvature on the heart are studied. At first, numerical solution of the blood flow by assumption of blood as incompressible and Newtonian fluid for steady and pulsatile inlet is done. Then by assuming LDL particles as dilute solute in the blood, LDL transport from artery lumen into arterial wall is studied. LDL accumulation and penetration into the vessel wall cause thickening of the walls and eventually eclipse it and its known as the first stage of atherosclerosis disease. The results show that low shear region occurs on inner wall... 

Carotid bifurcation is one of the most important bifurcations in human body which has a lot of curvature in some people. The common carotid artery bifurcates into an internal carotid artery (ICA) and an external carotid artery (ECA). The incidence of stenosis in carotid bifurcation and in particular in the internal carotid artery is of special importance. In the United States of America by 2006, nearly 700000 strokes occur each year, with about 160000 deaths and 20 to 30% of strokes are caused by stenotic carotid that cost estimated at $160 billion. The purpose of this thesis is to investigate in hemodynamic factors of blood flow such as velocity variation, vortex patterns, shear stress and... 

Motion of liquid drops into another fluid is of central importance in a variety of most commonly used industries. Vast applications of emulsions in food and drug industries as well as using of drops in liquid-liquid extraction processes and direct contact heat exchangers are examples in which dynamics of motion of drops play a significant role in operation and efficiency.
In present study, we consider the accelerated motion of Newtonian and non-Newtonian liquid drops experimentally. In order to find the effect of bulk fluid on the motion of drops, air and water are used as bulk fluid. The experiments have been done on Water, Ethanol, Ethyl acetate, n-Hexane and Toluene as Newtonian and... 

The mathematical analysis of the kidney has always been considered due to its complex performance. It’s about two decades that mathematicians work on the mathematical modeling of this tissue. Since Glomerular filtration of blood in the kidney has been regarded by physiologists for many years, they can access only to the qualitative data. Mathematicians can solve this problem by numerical modeling. In this research, an engineering model is presented for the analysis of this capillary network by investigating in the different scientific fields such as, physiology, medicine, computer science and mathematics.First of all, the homogeneous model introduced by Deen, are studied. The rate of the... 

Nowadays, cardiovascular diseases are among the most prevalent cause of death worldwide. Besides, atherosclerosis is a cardiovascular disease happening with the continuous narrowing of vessels, especially medium and large-sized arteries. Moreover, the human aorta is vulnerable to this phenomenon. Atherosclerosis happens when the excess LDL in the blood flow penetrates the arterial wall. Then, the LDL is oxidized, thereby recruiting monocytes as the response against oxidized LDL. After monocytes enter the arterial wall, they differentiate and become macrophages. Macrophages then transform into foam cells by ingesting the oxidized LDL. The fatty foam cells are eventually responsible for the... 

In this thesis, flow hemodynamic parameters and white blood cell deposition on the 3- D of coronary artries of heart coronary walls are studied. At first, numerical simulation of blood flow and without the presence of white cells is performed. Then, using the Lagrangian approach, white blood cells as solid particles are tracked considering forces such as drag force, weight, buoyancy, Saffman lift force, virtual mass in one way coupling method. this particle representive of white blood cells and play significant role in low density lipoprotein (LDL) deposition.The results show that a low shear region occurs on myocardial wall. maximum flow velocity near the bifurcation towards epicardial wall... 

In this study, three recent predictors of severity of coronary stenosis including fractional flow reserve (FFR), instantaneous wave free-ratio (iFR) and coronary flow reserve (CFR), are calculated for a number of patient-specific models of left coronary arteries. These patients are admitted to Tehran heart center. The main aim is presenting the optimum numerical and clinical detection technique to assess the severity of coronary stenosis. The effect of geometric features of stenosis is studied on the results of the FFR, iFR, and CFR in order to determine their accuracy. It is observed that CFR does not have a good estimate of the amount of disease. But, iFR, as a less risky test than FFR,... 

Problems with the mitral valve can make the heart less efficient at pumping blood around the body. Severe problems can lead to heart failure if the valve is not surgically repaired or replaced. A simple approximation of the heart geometry is used and the valve dimensions are based on reported measurements. The primary objective for this study is to design and simulate the opening and closing behavior of the mitral valve using 2D fluid-structure interaction (FSI) model using ADINA software in order to evaluate and investigate the hemodynamic performance and problems of mitral valve, in which the blood is described as a viscous incompressible fluid, and the mitral valve is described as an... 

In this dissertation, mass transport in cardiovascular system has been simulated using one-dimensional approach. As one-dimensional simulation has computation cost less than that of the three-dimensional simulations, and as it is more precise than lumped models, they are extensively used in the study of the phenomena in cardiovascular system. In addition, such an approach is more useful in the extraction of medical indices. In this study, a one-dimensional geometry of the systemic arteries has been used to solve momentum and continuity equations using characteristics method.
At first, the physiological data of the systemic arteries have been used to simulate a one-dimensional geometry... 

A large number of desalination plants have been established to overcome the drinkable water scarcity in the world. These plants produce saline water as effluent, which is often discharged into local sea water. One of the applicable methods to dispose these kinds of effluents is to install an inclined nozzle below the water’s surface. Hence, an inclined negatively buoyant jet (INBJ) forms which is often fully turbulent due to the high discharge velocity. Local environmental characteristics affect the dynamics and mixing behavior of INBJs. One of these characteristics is the sea bed slope, on which the present study has been focused. Large eddy simulations (LES) are performed in the present... 

Heart attack is considered as one of the most common reasons of morality all over the world. Coronary Atherosclerosis is known as the major causes of heart attack. The commence and proceed of this disease is related to cross of Low Density Lipoprotein. In this project, based on numerical simulation using ANSYS Fluent, hemodynamic variables and the rate of LDL particles penetration to porous wall of coronary artery is investgated. The geometry is the first bifurcation of Left Anterior Descending and is located on the supposed sphere that represents heart configuration. Sinsuidal variations of shere radii, simulates pulsating movement of heart. Heart diameter is supposed to remain constant... 

Atherosclerosis is a vascular disorder caused by inflammation of the arterial wall. This inflammation leads to the accumulations of low-density lipoprotein (LDL) cholesterol, monocytes, macrophages and fat-laden foam cells at the site of inflammation, often referred to as plaque formation. This work uses a mathematical model for simulating the deposition of atheroma plaque in coronary arteries. In this study, the effect of time average wall shear stress (TAWSS), oscillatory shear index (OSI), non-Newtonian characteristics of blood and variable hematocrit values on the occurrence of atherosclerosis in a three-dimensional coronary artery was numerically investigated. Simulations was conducted...