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    Investigation of the continuum-rarefied flow and isotope separation using a hybrid CFD-DSMC simulation for UF6 in a gas centrifuge

    , Article Annals of Nuclear Energy ; 2020 Ghazanfari, V ; Akbar Salehi, A ; Reza Keshtkar, A ; Mahdi Shadman, M ; Hossein Askari, M ; Sharif University of Technology
    Elsevier Ltd  2020
    Abstract
    UF6 gas flow in the total regions of a rotor with the radius of 0.1 m and the length of 1 m in axisymmetric and steady states was simulated using a new hybrid CFD-DSMC method in the OpenFOAM framework. Implicit coupled density-based scheme was performed for CFD method, and Variable Hard Sphere (VHS) and diffuse model were employed in DSMC method. Also, as an initial estimation, the local Knudsen number was applied to determine the interface location between the continuum-rarefied regions (r = 0.0855 m). Then it was modified (r = 0.084 m) to reduce the computational cost. The comparison results of pure CFD and CFD-DSMC methods illustrated that there were large differences between the flow... 

    Collagen-based highly porous hydrogel without any porogen: Synthesis and characteristics

    , Article European Polymer Journal ; Volume 43, Issue 3 , 2007 , Pages 877-889 ; 00143057 (ISSN) Pourjavadi, A ; Kurdtabar, M ; Sharif University of Technology
    2007
    Abstract
    In this contribution we have developed a collagen-based highly porous hydrogel by neutralizing the grafted poly(acrylamide-co-acrylic acid) after gel formation. Preparation of the hydrogels involved free radical polymerization of a combination of hydrolyzed collagen, acrylic acid (AA), acrylamide (AAm) and distilled water, in appropriate amounts and contained a crosslinking agent called N,N′-methylene bisacrylamide (MBA). The chemical structure of the hydrogels was characterized by means of FTIR spectroscopy, DSC and TGA thermal methods. Morphology of the samples was examined by scanning electron microscopy (SEM). Systematically, the certain variables of the graft copolymerization were... 

    Evaluation of variation of permeability in liquefiable soil under earthquake loading

    , Article Computers and Geotechnics ; Volume 40 , 2012 , Pages 74-88 ; 0266352X (ISSN) Shahir, H ; Pak, A ; Taiebat, M ; Jeremić, B ; Sharif University of Technology
    2012
    Abstract
    Liquefaction phenomenon is usually accompanied by large amounts of settlement owing to disruption of soil structure. In addition to that, large settlement also occurs by a significant increase in soil permeability during seismic excitation. To properly simulate the post-liquefaction settlement, it is important to take the compressibility properties of the liquefied sand as well as the permeability increase into account. Using initial permeability coefficient in the course of simulation of liquefaction leads to underestimation of settlement. In addition to that, using unrealistic values for permeability may cause erroneous predictions of other aspects of soil behavior. Therefore, an accurate... 

    Dynamic behavior of pile foundations under cyclic loading in liquefiable soils

    , Article Computers and Geotechnics ; Volume 40 , 2012 , Pages 114-126 ; 0266352X (ISSN) Rahmani, A ; Pak, A ; Sharif University of Technology
    Abstract
    In this paper, a fully coupled three-dimensional dynamic analysis is carried out to investigate the dynamic behavior of pile foundations in liquefied ground. A critical state bounding surface plasticity model is used to model soil skeleton, while a fully coupled (u- P) formulation is employed to analyze soil displacements and pore water pressures. Furthermore, in this study, variation of permeability coefficient during liquefaction is taken into account; the permeability coefficient is related to excess pore water pressure ratio. Results of a centrifuge test on pile foundations are used to demonstrate the capability of the model for reliable analysis of piles under dynamic loading. Then, the... 

    Numerical simulation of vortex engine flow field: One phase and two phases

    , Article Journal of Thermal Science ; Volume 18, Issue 3 , 2009 , Pages 226-234 ; 10032169 (ISSN) Najafi, A. F ; Saemi, S. D ; Saidi, M. H ; Sharif University of Technology
    2009
    Abstract
    Aiming at improving efficiency in combustion systems, the study on droplet behavior and its trajectory is of crucial importance. Vortex engine is a kind of internal combustion engine which uses swirl flow to achieve higher combustion efficiency. One of the important advantages of designing vortex engine is to reduce the temperature of walls by confining the combustion products in the inner vortex. The scopes of this investigation are to study vortex engine flow field as well as effective parameters on fuel droplet behavior such as droplet diameter, droplet initial velocity and inlet velocity of the flow field. The flow field is simulated using Reynolds Stress Transport Model (RSM). The... 

    Design and Fabrication of a Centrifugal Microfluidic System to Cell Lysis

    , M.Sc. Thesis Sharif University of Technology Khorrami Jahromi, Arash (Author) ; Saadatmand, Maryam (Supervisor) ; Eghbal, Manouchehr (Supervisor) ; Parsa Yeganeh, Laleh (Co-Supervisor)
    Abstract
    Cell lysis, as the first procedure of cell pretreatment, is a process that breaks cell membranes open thereby facilitating access to intracellular substances, such as DNA, proteins, and other components for further analysis to diagnose and treat diseases at early stages. Currently, there are several methods for cell lysis at macroscales. However, the time-consuming and expensive procedures as well as the large scal of the system are the main disadvantages of the systems. Recently, microfluidic systems have attracted considerable attention due to advantages associated with automation, integration and miniaturization of biomedical test protocols. Centrifugal microfluidics (Lab-on-a-Disc) is a... 

    Design, Simulation and Fabrication of a Centrifugal Microfluidic Platform for Separation and Studying of Circulating Tumor Cells

    , M.Sc. Thesis Sharif University of Technology Akbari, Ali (Author) ; Shamloo, Amir (Supervisor) ; Firoozbakhsh, Keikhosrow (Supervisor)
    Abstract
    In this project a centrifugal, microfluidic platform to the end of separation and studying circulating tumor cells is designed, modelled and analyzed. Circulating tumor cells (CTCs) are specific types of cancer cells which leave the original tumor and enter the blood stream. For the separation of CTCs, a novel anti-body separation technic has been used which targets the specific MCF7 CTCs using their corresponding Ep-CAM antibody. First the Ep-CAM antibody is coated on magnetic nanoparticles through a chemical bonding process. Afterwards the CTCs are exposed to their antibodies, through which they will bind together and form CTCs with magnetic characteristics. Finally through exerting an... 

    Design and Fabrication of a Centrifugal Microfluidic System to DNA Extraction

    , M.Sc. Thesis Sharif University of Technology Fathi Ganje Lou, Ali (Author) ; Farhadi, Fathollah (Supervisor) ; Saadatmand, Maryam (Supervisor) ; Parsa Yeganeh, Laleh (Co-Supervisor)
    Abstract
    Deoxyribonucleic acid (DNA) extraction, as one of the most important steps in modern molecular diagnostics, is the process by which DNA is separated from intracellular materials like proteins, membranes, and other materials contained in the cell. Microfluidic technology enables sophisticated, time-consuming and costly experiments with minimal use of raw materials, time and cost and acceptable accuracy. The predominant advantages of centrifugal microfluidic systems are utilizing centrifugal force to generate propulsion without the need for a pump, and eliminating the need for experts to run the system. Various fluidic operations such as valving, mixing, metering, heating, and sample... 

    Thermal Cyclic Effects on the Long-Term Behaviour of Elevated Floating Energy Pile Groups in Saturated Lightly Overconsolidated Clay by Centrifuge Modelling

    , Ph.D. Dissertation Sharif University of Technology Farivar, Alireza (Author) ; Jafarzadeh, Fardin (Supervisor)
    Abstract
    There is an increasing interest and use of energy foundations worldwide. Heat transfer from/to energy piles may cause plastic contraction of soft clay with a low overconsolidation ratio (OCR) during heating and cooling. This can influence pile-soil interaction due to thermally induced excess pore water pressure and changes of lateral stress acting on the pile.These thermally induced phenomena cause additional plastic settlement of the soil and pile. The irreversible settlement may cause serviceability or even ultimate limit state problems for floating energy piles whose capacity is mainly derived from shaft resistance. Due to intended operational needs or by accident, cyclic non-symmetrical... 

    Hydrodynamic Circuit Modeling of Surge Control System of a Centrifugal Compressor with Variable Gas Combination to Combine an Active Surge Control System with Surge Avoidance System

    , M.Sc. Thesis Sharif University of Technology Ghanbari, Arash (Author) ; Mazaheri, Karim (Supervisor)
    Abstract
    In this research, first, the performance map and surge line of 46M6 and 46MB8 multi-stage radial compressors, which have 6 and 8 stages, respectively, have been estimated and invarianted. Invarianting the performance map makes the performance curve and surge line of the compressor, unchanged from input conditions, including molecular weight, which is very important for control systems. Then, the hydrodynamic circuit of Compressor System C-3002 of Nouri Petrochemical Company was modeled according to the characteristics of its components by solving equations in MATLAB software. main working condition of the hydrodynamic circuit is close to Start of Life operating condition which has a... 

    Model Predictive Control Applications in Turbocompressor Control System

    , Ph.D. Dissertation Sharif University of Technology Sheikhbahaei, Reza (Author) ; Alasty, Aria (Supervisor) ; Vossoughi, Gholamreza (Supervisor)
    Abstract
    The purpose of this study is to develop model predictive control approach to control a turbocompressor. The turbocompressor which is consisted of a gas turbine and a centrifugal compressor is manufactured for providing the necessary pressure for gas transport via the gas transmission network. The turbocompressor control system regulates the compressor outlet pressure by controlling the rotational speed of the gas turbine, while preventing the surge phenomenon in the compressor. Surge is a serious instability in the compressor that is associated with periodic fluctuations in system variables and can cause heavy damage to expensive machine parts.In this research, model predictive control has... 

    The Study of Flow with Suspended Solid Particles through a Centrifugal Fan to Avoid Asymmetric Erosion of the Impeller and its Redesign to Improve its Endurance

    , M.Sc. Thesis Sharif University of Technology Mirzakhani, Hossein (Author) ; Darbandi, Masoud (Supervisor)
    Abstract
    Industrial centrifuge fans operate in various industries, specifically heavy industries such as pelletizing plants, steel mills, and cement plants. These fans transfer process gas in the production cycle. In some cases, due to their off-design working conditions, asymmetrical wear and failure happen on one side of the impeller's blades more than the other side. The most important reason is the heterogeneity of the entrance fluid's properties. One of the many critical parameters in this issue is the asymmetric distribution of particles between the two entrances of the fan. This research investigates the asymmetric erosion problem of a specific centrifugal fan with a double-suction side... 

    Particle dispersion dependency on the entrance position in bidirectional flow

    , Article Particulate Science and Technology ; Volume 31, Issue 6 , 2013 , Pages 576-584 ; 02726351 (ISSN) Dehghani, S. R ; Saidi, M. H ; Mozafari, A. A ; Soleimani, F ; Sharif University of Technology
    2013
    Abstract
    This article presents a process of numerically predicting and experimentally verifying the dispersion quality and penetration level of fuel particles entering and moving in various directions relative to vortex engine walls. If the length scale of particles considered in this study is not comparable to the chamber length and, furthermore, the density is ignored, the effect of the particle on the flow field can be neglected and a one-way solution will be viable for the problem. The solutions in each case are carried out to estimate the particle trajectory and parameters affecting it. The governing equations are converted to a set of nonlinear, coupled, ordinary differential equations (ODEs)... 

    Vibration and dynamic analysis of oil well drillstring considering coupled axial and torsional effects using cylindrical superelement

    , Article ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE) ; Volume 14 , November , 2013 ; 9780791856437 (ISBN) Ahmadian, M. T ; Ghorbani, Sh ; Firoozbakhsh, K ; Barari, A ; ASME ; Sharif University of Technology
    American Society of Mechanical Engineers (ASME)  2013
    Abstract
    In this paper axial and torsional vibrations of a drillstring are studied using cylindrical superelement. Drillstring vibration equation is derived by calculating kinetic and potential energy and work done by external forces on drillstring, and utilizing Hamilton's principle. The model is analyzed by implementing finite element technique with consideration drillstring weight, centrifugal force due to rotation of drillstring, axial force resulting from bit with the formation contact and torsional torque caused by the stick-slip phenomenon. To calculate the vibrational response of drillstring, a computational finite element scheme was developed. For a typical case of oil well drillstring, the... 

    Experimental and numerical investigation of radial flow compressor volute shape effects in characteristics and circumferential pressure non-uniformity

    , Article Scientia Iranica ; Volume 20, Issue 6 , 2013 , Pages 1753-1764 ; 10263098 (ISSN) Mojaddam, M ; Hajilouy Benisi, A ; Movahhedy, M. R ; Sharif University of Technology
    Sharif University of Technology  2013
    Abstract
    In this article, the effects of volute cross section shape and centroid profile of a radial ow compressor volute were investigated. The performance characteristics of a turbocharger compressor were obtained experimentally by measuring rotor speed and ow parameters at the inlet and outlet of the compressor. The three-dimensional ow field model of the compressor was obtained numerically solving Navier-Stokes equations with SST turbulence model. The compressor characteristic curves were plotted. For model verification, the results were compared with experimental data, showing good agreement. Modification of a volute was performed by introducing a shape factor for volute cross section geometry.... 

    Evaluating the effect of ultrasmall superparamagnetic iron oxide nanoparticles for a long-term magnetic cell labeling

    , Article Journal of Medical Physics ; Volume 38, Issue 1 , 2013 , Pages 34-40 ; 09716203 (ISSN) Shanehsazzadeh, S ; Oghabian, M. A ; Allen, B. J ; Amanlou, M ; Masoudi, A ; Daha, F. J ; Sharif University of Technology
    2013
    Abstract
    In order to evaluate the long-term viability, the iron content stability, and the labeling efficiency of mammalian cells using magnetic cell labeling; dextran-coated ultrasmall superparamagnetic iron oxide (USPIOs) nanoparticles with plain surfaces having a hydrodynamic size of 25 nm were used for this study. Tests were carried out in four groups each containing 5 flasks of 5.5 × 10 6 AD-293 embryonic kidney cells. The cell lines were incubated for 24 h using four different iron concentrations with and without protamine sulfate (Pro), washed with phosphate-buffered saline (PBS) and centrifuged three times to remove the unbounded USPIOs. Cell viability was also verified using USPIOs. There... 

    Zero D and 3D analysis of the centrifugal compressor of a gas turbine and its evaluation using experimental results

    , Article ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011, 11 November 2011 through 17 November 2011 ; Volume 1 , November , 2011 , Pages 897-906 ; 9780791854877 (ISBN) Karrabi, H ; Pourfarzaneh, H ; Hajilouy Benisi, A ; Sharif University of Technology
    Abstract
    In compressor design, it is necessary to simulate the compressor before manufacturing and performing experimental studies. One of the most efficient and common modeling methods is zero D analysis using scaling method with constant coefficients. Although it is efficient in the vicinity of the design point, its results are not acceptable in the off design points due to the growing error by getting away from design points. In this research, a novel zero D analysis method is developed predict accurately the compressor performance not only in the design point but also in the off design pint. In this method, variable coefficients are used instead of constant coefficients, which are obtained based... 

    Numerical study of slip factor model, effect of inlet total pressure and gas composition on the performance curve of centrifugal compressor

    , Article ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 ; Volume 1 , 2011 , Pages 885-895 ; 9780791854877 (ISBN) Aligooda, M. R ; Moshnofi A., M. H ; Karrabi, H ; Soleimani Tehrani, M. R ; ASME ; Sharif University of Technology
    Abstract
    Development of hardware and CFD codes, especially in turbulence model and optimization of numerical codes has led to increment in usage of CFD which is capable of simulating different experimental situations take place at laboratory. Particularly in issues related to turbo machinery, twodimensional test of blades, three-dimensional investigation of different stages and studying the effect of different parameters are very costly. By means of CFD modeling all these issues are accessible. Actual flow within the compressor is three dimensional and fully turbulent due to geometry complexity, flow velocity and viscosity. For this reason it has become more and more popular to perform 3D numerical... 

    Numerical investigation on the behavior of the gravity waterfront structures under earthquake loading

    , Article Ocean Engineering ; Volume 106 , September , 2015 , Pages 152-160 ; 00298018 (ISSN) Khosrojerdi, M ; Pak, A ; Sharif University of Technology
    Elsevier Ltd  2015
    Abstract
    Abstract Lateral Spreading, which usually occurs as a consequence of liquefaction in gently sloped loose saturated sand layers, is known to be a major source of earthquake-induced damages to structures such as quay walls, bridge piers, pipelines, and highway/railways. Therefore evaluation of the liquefaction potential and using appropriate methods for prediction of the adverse consequences of lateral spreading is of great importance. In this study, numerical modeling has been used to study lateral spreading phenomenon behind rigid waterfront structures. Coupled dynamic field equations of the extended Biot's theory with u-P formulation are used for simulating the phenomenon. A fully coupled... 

    Chlorophyll-based wicking sensing bioplatform coupled with a smartphone-based sample-to-answer analytical device for on-site detection of picric acid

    , Article Biosensors and Bioelectronics: X ; Volume 11 , 2022 ; 25901370 (ISSN) Shafizadeh, M ; Abbasi Moayed, S ; Hamzei, Z ; Keshavarz, A ; Yousefi, S ; Hormozi Nezhad, M. R ; Golmohammadi, H ; Sharif University of Technology
    Elsevier Ltd  2022
    Abstract
    The development of inexpensive, equipment-free, portable, and user/environmentally-friendly analytical devices that can be efficiently utilized for on-site detection of PA is still a great challenge. To address these unmet demands, we have developed a smartphone-based disposable sensing bioplatform through immobilization of chlorophyll in a cotton thread for fluorescent monitoring of picric acid (PA). The fluorescence quenching of chlorophyll upon increasing the PA concentration based on the inner filter effect was considered as the sensing strategy in the developed sensor. The fabricated thread-based microfluidic sensing bioplatform was further coupled with a compact, low cost, portable,...