Sharif Digital Repository

This research studies a 3D channeled myocardium scaffold with computational fluid dynamics. It proposes a mathematical model to evaluate the impact of oxygen carriers and scaffold geometry on cell growth in a 3D cardiac construct. The modeling results show that using 5.4% perfluorocarbon oxygen carrier (PFC) has increased cardiac cells density 15% of the initial seeded cells comparing to pure culture medium without PFC supplementation. Effects of the scaffold geometry on cell density in the construct were examined by increasing channel numbers and changing the construct length. The results show that increasing channel numbers (by 50% decreasing channels diameter and wall to wall spacing) the... 

Phase change and deposition of solid particles in liquid flows are undesirable in industrial and natural processes and hazardous in some cases. Considering the intentions to petroleum exploration in deep waters such as Caspian Sea, the Gulf of Mexico and North Sea, precipitation and deposition of wax crystals in petroleum and gas pipelines is a real concern due to the fact that during production, oil is exposed to more intense temperature gradient (the dominant mechanism in wax deposition) and its heavier components change their phase to solid and deposit. Wax deposition in production lines starting at crude oil storage tanks is not accepted due to reduction in production rate and... 

Conventional MRI has been used to diagnose different types of brain injuries. However these methods have generally failed to diagnose mild types of injury. We are working on the specification of mild traumatic brain injury, using diffusion MRI data, based on a multi compartment simulation of white matter tissue. This effort is essential for better understanding of underlying tissue micro-structure changes in patients with trauma. Some studies have been used in similar data fitting approaches in order to estimate axon diameter distribution. Specifically, a comparative study between different Compartment Models has shown that “ActiveAx” model has the best agreement with underlying tissue... 

In this study, the effect of mix design parameters and the mechanical properties of roller-compacted concrete (RCC) were considered to evaluate its water permeability coefficient. For this purpose, over 400 laboratory specimens were prepared and tested. A formula was proposed to predict the permeability coefficient of RCC by considering the main parameters. Moreover, artificial neural network (ANN) was constructed to model the permeability coefficient of RCC based on its mix design constituents and the test results. The algorithm obtained from tests results were verified independently using extra specimens. Furthermore, Taguchi method and analysis of variance (ANOVA) were used to determine... 

With the rapid progress of technology, the fabrication of smaller electronic and mechanical systems becomes more necessary. To make a small-scale system with better performance, one way is to create it from molecular components. In recent decade, many attempts have been devoted to the fabrication of molecular machines for manipulation of particles at nanoscales. In this project, the motion of two of most basic nanocars namely the Nanocar and the Nanotruck were simulated on gold and silver substrate at different conditions, both of four wheels and the nanotruck chassis is flexible. In the first chapter of this report, some of the most important natural and artificial machines are mentioned... 

Molecular communication which is inspired by nature has emerged as a promising field in recent years for its potential applications in medicine, environment, tissue engineering, industry and so on. In molecular communication, molecules are the information carriers. One of the mechanisms of movement of molecules that does not require any infrastructure is Diffusion. Diffusion-based molecular communication in which molecules diffuse in the medium in order to reach the receiver, has two major problems: delayed and lost molecules. Due to the randomness of diffusion, molecules are usually received with varied delays, their order of reception is different from the order of transmission and even... 

Molecular communication is a new paradigm in communication science, which studies opportunities and challenges of information transmission in nanoscale. Unlike the classical communication, which uses electro-magnetic waves as signal carriers, in this new method of communication, tiny agents in molecular scale are the main information barriers. In this sense, studying molecular communication requires theoretical development and updating some well-known techniques of classical communications.Although there have been some successful attempts to implement communication systems based on molecular communication, the field is still in the theoretical development phase. In this thesis, we have tried... 

Traffic flow modeling on different levels was always the topic of many studies. In this regard, many researchers have tried to eliminate traffic problems by developing precise models. Therefore, in this study and in its two major parts, we developed two models: one macroscopic and one microscopic. Like previous studies, the main purpose here was the development of traffic flow models that have better precision and give more information about the mechanism behind the traffic phenomena. Our focus was on the free spaces in front of drivers which were considered in a macroscopic traffic flow model and resulting microscopic traffic flow model.First part, addresses the first-order extension of the... 

A great deal of information are continuously generated by users in different contexts such as social networks and online service providers in terms of temporal marked events. These events indicate that what happened to who by when and where.Modeling such events and predicting future ones has interesting applications in different domains such as item recommendation in online service providers and trending topic prediction in online social networks. However, complex longitudinal dependencies among such events makes the prediction task challenging. Moreover, nonstationarity of generative model of events and large size of events, makes the modeling and learning the models challenging.In this... 

Thermal and compositional variations through porous media are the main causes of bringing changes in the density of the fluid in place and arising in density-driven flow. This phenomenon is usually called thermohaline or thermosolutal convection (TC). When the flow is driven by the concentration gradient of two different compositions the problem is called double-diffusive convection (DDC). This phenomenon can be observed in several applications as in geological carbon dioxide sequestration, geothermal systems, underground thermal energy storage, salt mining, salt domes, groundwater management, waste disposal, and seawater intrusion.Despite that TC processes are three-dimensional by nature... 

In this study, ZIF-8 was synthesized at room temperature and Then ZIF-8/PEGDA mixed matrix membranes with 5 and 10% of ZIF-8 were prepared by UV photopolymerization to analyze the separation CO2 from natural gas for the first time. The permeation results of gases in mixed matrix membranes in the temperature range of 35-75 degrees centigrade and in pressure ranging from 4-15 bar show the permeability of gases in mixed matrix membranes with 5 and 10% increase more than a pure polymer nearly 14.3 and 31%, respectively, But, CO2=CH4 selectivity decreases. The gas sorption in ZIF-8 was measured in the temperature range up to 75 ◦C and pressure ranging from 2-5 bar. The adsorption isotherm follows... 

We present a new high signal to noise ratio spectroscopic survey of the Northern hemisphere to probe the Local Bubble and its surroundings using the 5780Å and 5797Å Diffuse Interstellar Bands (DIBs). We have observed 432 sightlines to a distance of 200 pc over a duration of 3 years. In this study, for both inside and outside the Local Bubble, we establish the 5780and 5797correlations with Na i, Ca iiand E(B-V). The correlations show that among all neutral and ionized atoms, the Na ihas more similarity with 5780and Ca iihas strong correlation with 5797, which suggest that the ionization level of 5797is more than 5780. We study the 5780correlation with 5797, which shows a tight correlation... 

Transient liquid phase (TLP) bonding of Al2024-T6 alloy, using gallium interlayer, has been investigated. Bonding experiments were carried out using two basic methods; Conventional and Temperature gradient TLP bonding. Optimum values of isothermal solidification temperature and time, pressure, surface roughness, heating rate and homogenizing conditions were determined in conventional TLP bonding experiments. Aluminum oxide layer was not removed before TLP bonding to prevent gallium attack.this layer is crashed during bonding. Al2O3 particles are not soluble in the liquid and are pushed into liquid by solidification front progression. These particles are accumulated in grain boundaries and in... 

Molecular diffusion of gases in crude oils plays a crucial role in several oil recovery processes especially in cold-based production process. Nowadays, heavy oil is a considerable part of the world hydrocarbon reservoirs and its importance increases as the ordinary oil reserves decrease. The main obstacle in heavy oil production is its low mobility (i.e. high viscosity). This difficulty can be easily solved by injecting gas solvent in these reservoirs. However, experimental data concerning CO2 diffusivity in heavy oils due to the tedious nature of diffusivity measurements are relatively rare in the open literature. In this work, a comprehensive experimental investigation of the effective... 

Gas leak explosion is major risks in closed environment in the chemical industry. One of the fundamental principles of safety is control of ignition sources using special protective equipment in areas where possible flammable gases or vapors are there. Computational fluid dynamics is used in this project to evaluate and analyze the risks associated with gas distribution. Ventilation effect has been studied by computational fluid dynamics on gas cloud formed by leakage of flammable in hazardous areas. To demonstrate the accuracy of calculations performed by computational fluid dynamics, the results are validated by experimental data. The simulated results for gas dispersion are found to be in... 

Two phase flow through porous media is one of great interests which have been studied for decades in petroleum sciences and even other fields, e.g. hydrology and physics, to solve problems such as enhanced oil recovery, contaminated groundwater or CO2 sequestration projects. Flow in porous media typically predict by means of Darcy’ law which in two phase flow lead to equations such as Buckley-Leverett or Koval, but today it is well approved that compact prediction of flow pattern by these equations may be accompanied by enormous errors and it’s because flow in certain condition is fractal. In this work a new mechanistic model has been used for simulating of immiscible drainage process and... 

Recently, the nano-bio communication networks have received significant attention. Among different communication mechanisms proposed for nano communication, diffusion based molecular communication (DMC) is the most promising scheme. This thesis focuses on DMC and first proposes a theoretical model for this scheme. In the next part of the thesis, inspired by the molecule transport mechanisms in the biological cells, two biosynthetic modulator structures are proposed.In first structure, an ion channel based modulator for DMC is proposed which controls the rate of molecule release from the transmitter by modulating a gating parameter signal. The corresponding average modulated signal, i.e., the... 

Moderate and Intense Low-oxygen Dilution(MILD) is the new member of combustion field. Highly preheated reactants and lowering the oxygen level in MILD combustion has some promising advantages. In this study the MILD burner, Jet-in-Hot-Coflow(JHC), is taken as the main test case. In this Research, Eddy Dissipation Concept combustion model ,introduced by Magnussen et al,is investigated in detail and governing equations are re-extracted. EDC combsution model due to moderate compuational cost in comparison with other combustion model and well prediction ability has drawn attention. Simulations on the Jet-in-Hot-Coflow(JHC) has shown the promising performance of the EDC combustion model. It seems... 

Corrosion is a main problem for oil and gas industries at refineries and petrochemical process. Presence of sulfur compounds in crude oil and creation a corrosive environment for steel structure, caused failure and unfortunate damages. H2S which present at cracking and sweetening process in sour feed obtain hydrogen atoms that can diffuse into steel structure which involve with its instruments and consequent to hydrogen damage .distribution and storage of these sour environments can be done by high strength low alloy steel (HSLA).Electrochemical hydrogen permeation test were performed to measure the hydrogen permeation current through A106/GR B pipeline steel in the electrolytes simulating... 

Gas condensate reservoirs show very complex behavior as wellbore pressure falls below the reservoir fluid dew point pressure and consequently liquid phase appears near the wellbore. Since pressure drawdown is the largest near the wellbore, therefore, this region is the first that experience the liquid dropouts. With continuing the production, reservoir pressures at the other parts of the reservoir fall below the dew point pressure and as a result, condensate appears at these regions. The more the condensate accumulates near the wellbore the more decreasing the gas relative permeability occurs. Condensate accumulating does as a liquid barrier and causes not only decreasing the gas production;...