Sharif Digital Repository

In this study, the numerical simulation of cavitating flows for cryogens fluids is performed. The algorithm employs the homogenous, multiphase Euler/Navier-Stokes equations with the interface capturing method. The thermodynamic and thermal effects substantially impact the cavitation dynamics of cryogenic fluids and therefore these effects should be considered by solving the energy equation in conjunction with the mass and momentum conservation, and updating the fluid physical properties. Here, two cavitation modeling strategies, namely, the barotropic cavitation model and the transport equation-based model are used. Both laminar and turbulent cavitating flows are studied in this work. For... 

Importance: Age related cataract is the major cause of blindness worldwide.in recent years several studies has been done with the aim of understanding the cataract process, but no attempts has been done for simulation and study of the vitreous aging and its effect on cataract.
Objective: To investigation and determination of effective mechanism for increasing oxygen in vitreous humor and simulation the oxygen tension changes with vitreous degeneration with age or vitrectomy.Methods: Effects of changes in chemical composition of vitreous humor with age or vitrectomy on oxygen solubility is studied by thermodynamic relations. The posterior segment of the eye is modeled using transport... 

In this study the effect of nanoparticles on the mass transfer of dispersed phase in the liquid-liquid extraction systems, containing toluene with acetic acid as dispersed phase and saturated water of toluene as continues phase was investigated. For the ease of dispersion of nanoparticles in nonpolar organic dispersed phase, with the use of a novel method, hydrophobic tiania nanoparticles were synthesized and during producing with the sole-gel method were modified by adding Tetraethyl Ortho titanate as modifying agent, also the smallest hydrophobic nanoparticles of magnetite were synthesized by co-precipitating method and then, under optimum thermal condition were coated by adding Oleic... 

Dissemination of an analyte under the laminar flows plays a major role in measuring and assessment of biological fluids such as sample preparation in the context of microfluidic systems. Due to the development of manufacturing technology in the Lab-on-a-chip devices, the production of rectangular microchannels with finite aspect ratios and micron and submicron sizes has been provided by which the effect of electrokinetic phenomena on concentration distribution will be magnified in these systems. On the other hand, these biofluids are viscoelastic and show extraordinary flow behaviors, not existing in Newtonian fluids and adopting appropriate constitutive equations these exotic flow behaviors... 

In the nuclear industry, gas centrifuges are considered of high importance for the purpose of uranium enrichment. Today, with advances in science and technology, the use of gas centrifuges for separating isotopes other than uranium, is so common. With respect to the use of conventional methods such as Pancake equation in calculating the velocity profile in centrifuges, it is needed that A^2=(MV^2)/2RT≫1 (M: Feed molecular weight; V: Peripheral speed of centrifuge; T: Mean temperature of feed; R: The universal constant of gases). While the molecular weight of the feed mixture gets lower, the A2 parameter gets closer to one. So, other methods for modeling the behavior of the gas in the... 

In this work, flow transport, distribution, and dissolution of non-aqueous phase liquids (NAPLs) in heterogeneous porous media were modeled by focusing on the dissolution process in pore-level and field scale. First, by adopting advection-diffusion and mass transfer equations, dissolution process and NAPL distribution were investigated in a heterogeneous porous media using pore network modeling. The 2-D developed model was based on observations of micromodel tests. The pore scale simulator which adopted by this work was improved in some aspects in comparison to previous models in the literatures. First, in the phase displacement, by considering more realistic geometries for pore structure... 

Atherosclerosis is one of the most important and common causes of death in the world. Atherosclerosis typically affects medium and large arteries in the body and it leads to plaque formation in arterial wall. The first stage of plaque formation has been related to accumulation of low density lipoproteins in arterial wall.
The purpose of this research is presenting a four-layer model to describe the LDL transport in the arterial wall. The endothelium, intima, internal elastic lamina (IEL) and media are all treated as macroscopically homogeneous porous media and the volume-averaged porous media equations are employed to model various layers. The physiological parameters within the various... 

In this thesis, hemodynamic parameters of flow and deposition of low density lipoproteins (LDL) on wall of coronary arteries with taking into account their curvature on the heart are studied. At first, numerical solution of the blood flow by assumption of blood as incompressible and Newtonian fluid for steady and pulsatile inlet is done. Then by assuming LDL particles as dilute solute in the blood, LDL transport from artery lumen into arterial wall is studied. LDL accumulation and penetration into the vessel wall cause thickening of the walls and eventually eclipse it and its known as the first stage of atherosclerosis disease. The results show that low shear region occurs on inner wall... 

The effects of gravity and inertia dominate our experiences of the physical world. But as systems are reduced in size, phenomena such as diffusion, surface tension and viscosity become ever more important; at the microscale they can dominate and result in a world that operates very differently from the macroscopic world. Kidney is one of the vital organs in which fluid and mass transfer occur between blood flow in microvessels and urine in microchannels called nephron. The present work is aimed at applying microchannel theory to study renal system. First, a n efficient numerical orthogonal collocation method has been employed to solve the steady-state formulation of electrolyte transport in... 

Transport phenomena i.e. momentum, heat and mass transfer are occurring inside the eye constantly. Any disturbance in each of these could lead to diseases or ocular problems. Konwledge of transport phenomena can help surgeons and specialists to identify problems more easily and cure the problems effectively. Further more, these phenomena have a great impact on drug delivery inside the eye. Therefore deep understanding of them makes investigation of different therapies easy and convenient. Consequently this understanding could lead to choose the best method and route of administration available. A precise model which is in consistence with the real human eye has been developed and the ocular... 

This is a theoretical study on heat and mass transfer in electrokinetically driven microfluidic devices with particular consideration to the lab-on-a-chip (LOC) applications. Special attention is given to disclose the effects of the fluid rheology and the aspect ratio of the rectangular geometry on the surface reaction kinetics and the temperature rise due to the Joule heating. Along this line, two different viscoelastic constitutive equations namely PTT and FENE-P models along with the power-law viscosity model are being considered. The secondary aims also include exploring the influences of the fluid properties variations throughout the channel cross section on the hydrodynamic and thermal... 

In recent two decades, with developments in micro and nano scale fabricating techniques, use of microfluidic systems is increasing in different fields. How to drive fluid is a hard question because of high pressure drop in micro scale. Different methods has been suggested to solve this problem, among which, electroosmotic pump is preferred because of its advantages. One of the main applications of microsystems is in biomechanical devices like microreactors which are usually working with non-Newtonian fluids. The cross section of these devices are most often close to rectangular shape.Therefor, in this study,Hydrodynamic charactristics and mass transport of non-Newtonian fluids under... 

Nowadays, technology has facilitate the miniaturization of laboratory systems, medical and drug delivery tools. As a result, researchers are interested to miniaturize these tools. The extensive research in this field led to invention of lab-on-a-chips, which with the size of a few µm to a few mm, can do multiple tasks in human body. One of most important components of these devices, is microreactor. A wide range of measurements and reactions in microreactors, need to bind with the receptors at the surface of the cylindrical microchannels. For this purpose, this study, investigates the effects of surface heterogeneity on microreactors performance. In this Thesis, the governing equations were... 

Due to largre number of patients treated by dialysis and its significant increasing progress, dialysis efficiency and patients' life quality are of great interest.Dialyzer, the dialysis beating heart, has the role of cleaning blood by removing toxic solutes and balancing volume of bood's water through hollow fiber membranes. In this thesis, firstly we tried to focus on performance characteristics of dialyzer by studying effective parameters influencing dialyzer efficiency and ultimately we set two important performance characteristics, ultrafiltration coefficient and solute clearance, as our goal parameters for evaluating dialyzer's yield. To this purpose, we designed an experimental set...