Sharif Digital Repository

The Large Hadron Collidor (LHC) will increase its luminosity to more than 10e35 cm-2 s-1. The large amount of data rates will provide enough datasets needed to probe rare Higgs processes, study the scattering of longitudinally polarized W bosons and physics beyond the standard model(BSM). In the upgraded version of the LHC, called High Luminosity LHC (HL-LHC), the number of simultaneous interactions per bunch crossing, aka pile-up, increases to 140-200. The large number of pile increases the possibility of confusion in distinguishing vertexes of interest due to the contamination from non-interesting vertexes. One of the methods to mitigate the pile-up, complementary to the precision tracking... 

Nanopositioning is technology of positioning & manipulation of Nano-scale object. This technology can be considered as one of the fundamental necessities in Nano & Micro research and fabrication and made lots of unbelievable advancement in researches and technologies. There are lots of mechanical systems designed for large scale positioning with sub millimeter resolution, but when it’s come to Nano scale, the range of access should be limited to some micrometer. Also in Nano-scale motion some difficulties like backlash, stick-slip and friction is phenomenon. For increasing the workspace using coarse and fine positioning systems may be an appropriate method. In this method a fine positioning... 

In this thesis, optimum set of satellite constellations for regional navigation has been investigated. The cost function is the required multiple coverage for navigation in the Iran region with the lowest possible positioning error. In the satellite navigation systems the GDOP (Geometric Dilution of Precision) is a quantitative measure which is usually used to determine the effect of satellites’ orbits geometry on position error estimation. The lower the GDOP, the more precise the navigation would be. In fact, GDOP relates computed satellite-receiver range error to position estimation error. This thesis has two major parts; modeling and optimization. In the modeling of the problem,... 

The development of technologies and some defects in medicine caused to emerge a new approach called precision medicine. Unlike the traditional medicine, medical experts do best treatment for each patient based on his genetic characteristics in this approach. Predicting drug response on cancer cell lines is one of the most vital challenges in this area. Various approaches have been proposed to construct predicting models while the substantial distinctions between resistant and sensitive cell lines had been neglected in them. Here, we propose a new approach for constructing the predictive model. In our approach, we utilized the distinctions between sensitive and resistant cell lines and also... 

Nanopositioning is a technology for moving a target object within nanometer (10-9 meter) resolution. Nowadays nanopositioning stages have emerged as an important technological advancement in hi-tech applications, including scanning probe microscopy, lithography, nanometrology, fabrication and assembly of nanostructures and beam steering for optical communication systems. To achieve nanometer resolution the stage must focus on a few tens of micrometers travel range. The combination of piezoelectric actuators and monolithic compliant mechanisms can provide a smooth motion without friction, wear, and backlash. So, piezo-driven compliant mechanisms are used widely in nanopositioning systems. The...