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    Serological assays and host antibody detection in coronavirus-related disease diagnosis

    , Article Archives of Virology ; Volume 166, Issue 3 , 2021 , Pages 715-731 ; 03048608 (ISSN) Dowlatshahi, S ; Shabani, E ; Abdekhodaie, M. J ; Sharif University of Technology
    Springer  2021
    Abstract
    Coronaviruses (CoV) are a family of viral pathogens that infect both birds and mammals, including humans. Seven human coronaviruses (HCoV) have been recognized so far. HCoV-229E, -OC43, -NL63, and -HKU1 account for one-third of common colds with mild symptoms. The other three members are severe acute respiratory syndrome (SARS)-CoV, Middle East respiratory syndrome (MERS)-CoV, and SARS-CoV-2. These viruses are responsible for SARS, MERS, and CoV disease 2019 (COVID-19), respectively. A variety of diagnostic techniques, including chest X-rays, computer tomography (CT) scans, analysis of viral nucleic acids, proteins, or whole virions, and host antibody detection using serological assays have... 

    Improved design of an outer rotor six-phase induction motor with variable turn pseudo-concentrated windings

    , Article IEEE Transactions on Energy Conversion ; Volume 37, Issue 2 , 2022 , Pages 1020-1029 ; 08858969 (ISSN) Rezazadeh, G ; Tahami, F ; Capolino, G. A ; Nasiri Gheidari, Z ; Henao, H ; Sahebazamani, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2022
    Abstract
    In this paper, a novel six-phase outer rotor induction motor equipped with pseudo-concentrated windings is introduced as a robust, reliable, and low-cost solution. Multiple aspects of the proposed motor structure have been investigated such as a design algorithm and an analytical modeling based on the modified winding function considering the skew effect. The effect of using variable number of turns for the coils has been examined on the pseudo-concentrated windings. An appropriate optimization problem has been also defined to maximize the power factor and efficiency and to minimize the output torque ripple. The designed motor has been fabricated to verify the accuracy of the design... 

    Feasibility of infrared tracking of beating heart motion for robotic assisted beating heart surgery

    , Article International Journal of Medical Robotics and Computer Assisted Surgery ; Volume 14, Issue 1 , February , 2018 ; 14785951 (ISSN) Mansouri, S ; Farahmand, F ; Vossoughi, G ; Ghavidel, A. A ; Rezayat, M ; Sharif University of Technology
    John Wiley and Sons Ltd  2018
    Abstract
    Background: Accurate tracking of the heart surface motion is a major requirement for robot assisted beating heart surgery. Method: The feasibility of a stereo infrared tracking system for measuring the free beating heart motion was investigated by experiments on a heart motion simulator, as well as model surgery on a dog. Results: Simulator experiments revealed a high tracking accuracy (81 μm root mean square error) when the capturing times were synchronized and the tracker pointed at the target from a 100 cm distance. The animal experiment revealed the applicability of the infrared tracker with passive markers in practical heart surgery conditions. Conclusion: With the current technology,... 

    , M.Sc. Thesis Sharif University of Technology Mohammad Alippour Ahari, Roua (Author) ; Eshghi, Koorosh (Supervisor)
    Abstract
    The focus of this research is to present a model to verify the acceptance of projects with time and cost dependency on the usage of equipments. Decision on these projects is based on a dynamic programming in which at each stage, the profit of available projects in this stage, equipment value and the best choice of future stage are decision keys. In other words, after the completion of a project, it should be decided between doing a project or selling the equipment and leaving the remaining projects. For each projects, there is a product network that includes projects jobs and operations. After accepting projects, equipments of the projects will not be renewed and the usage of the equipments... 

    Nonlinear Performance of 3-D Steel Structures by Scaled Nonlinear Dynamic Procedure

    , M.Sc. Thesis Sharif University of Technology Hashemian, Behdad (Author) ; Mofid, Masoud (Supervisor)
    Abstract
    It is well known that the most rigorous method to assess the performance and to predict the seismic demands of a structure subjected to earthquake is nonlinear time history analysis. However, this technique is accompanied by complexities and difficulties in evaluating the seismic demands of structures and requires superior knowledge and skill. As a result, in recent years, nonlinear static analysis has been proposed in performance based design procedures. One of the primary assumptions of nonlinear static procedures is that the behavior of a structure with multiple degrees of freedom (MDOF) subjected to seismic ground motion can be estimated from the response of an oscillator with a single... 

    Design and Modeling of a Solar Combined Cooling, Heating and Power System and it’s Validation with Empirical Results

    , M.Sc. Thesis Sharif University of Technology Yassaghi, Hamed (Author) ; Saboohi, Yadollah (Supervisor)
    Abstract
    Due to the growth of energy consumption the use of new technologies and efficient energy conversion is necessary. An example of efficient energy conversion technology is CCHP (Combined Cooling, Heating and Power). The aim of the present research work is to develop a model that could be applied for optimal design of a hybrid CCHP system which would be Solar Combined Cooling, Heating and Power (SCCHP). In order to do so,microturbine power system, cooling and heating equipment’s such as absorption system and heat exchanger and also solar collector have been considered as an integral part of the system. The objective of the application of the model has been to identify proper sizing of all... 

    A Train Sequencing and Stop Scheduling Model inDouble Track Railway Lines by hHybrid GRASP-VNS Meta-Heuristic

    , M.Sc. Thesis Sharif University of Technology Hassannayebi, Erfan (Author) ; Kianfar, Fereydoon (Supervisor)
    Abstract
    The train scheduling problem is one of the most important scheduling problems in the transportation systems. The goal of train scheduling problem is generating a feasible timetable which consists of train departure times and determining the best station to stop. Optimizing the railway capacity is one of the most important goals in train scheduling phase. The sequence of dispatching trains and stopping schedule are the main factors that can affect railway capacity on double track lines. In this thesis, a double-track train sequencing problem is studied in order to maximize the railway capacity, subject to a set of operational requirements. This research proposes a flexible flow shop... 

    Design and Implementation of an Auto-Grasping Algorithm for a Robotic Laparoscopic Instrument

    , M.Sc. Thesis Sharif University of Technology Amirkhani, Golchehr (Author) ; Farahmand, Farzam (Supervisor)
    Abstract
    The main goal of this project is to design and implementation of the tissue auto-grasping algorithm for a wristed laparoscopic instrument. In this algorithm, the difference between the pinch forces of two jaws was taken into account when the pull force direction corresponding to the rod instrument direction was changed. The term ‘Tissue auto-grasping’ means automatic adjustment of the pinch force corresponding to the pull force exerted on the tissue by the robotic surgical instrument, so that slip and exerting excessive force on the tissue are prevented. In this study, obtaining the pinch force is based on the proximal force-sensing technique. For this reason, the force model of wristed... 

    Application of a continuous kinetic model for the hydrocracking of vacuum gas oil

    , Article Petroleum Science and Technology ; Vol. 32, Issue. 18 , 2014 , Pages 2245-2252 ; ISSN: 10916466 Arefi, A ; Khorasheh, F ; Farhadi, F ; Sharif University of Technology
    Abstract
    Hydrocracking is one of the most versatile petroleum refining processes for production of valuable products including gasoline, gas oil, and jet fuel. In this paper, a five-parameter continuous lumping model was used for kinetic modeling of hydrocracking of vacuum gas oil (VGO). The model parameters were estimated from industrial data obtained from a fixed bed reactor operating at an average temperature of 400°C and residence time of 0.3 h. Product distributions were obtained in terms of the weight fraction of various boiling point cuts. The model parameters were estimated using the Nelder-Mead optimization procedure and were correlated with temperature. Comparison of experimental and... 

    Facile synthesis of highly substituted 2-pyrone derivatives via a tandem Knoevenagel condensation/lactonization reaction of β-formyl-esters and 1,3-cyclohexadiones

    , Article Tetrahedron Letters ; Vol. 55, issue. 18 , April , 2014 , p. 2908-2911 ; ISSN: 00404039 Moghaddam, F. M ; Mirjafary, Z ; Javan, M. J ; Motamen, S ; Saeidian, H ; Sharif University of Technology
    Abstract
    A mild and efficient tandem process for the synthesis of new highly substituted 2-pyrones starting from commercially available 2-arylacetic acids has been developed. The synthesis is based on the Knoevenagel condensation of 1,3-cyclohexadiones with various β-formyl-esters, followed by lactonization in the presence of nano ZnO (20 mol %). Moderate to high yields and readily available cheap starting materials are the key features of the present method  

    Precipitated asphaltene amount at high-pressure and high-temperature conditions

    , Article Energy and Fuels ; Vol. 28, Issue. 3 , 2014 , pp. 1596-1610 ; ISSN: 08870624 Tavakkoli, M ; Panuganti, S. R ; Taghikhani, V ; Pishvaie, M. R ; Chapman, W. G ; Sharif University of Technology
    Abstract
    In the upstream asphaltene flow assurance community, both academics and industries are actively involved to predict the asphaltene deposit profile in wellbores and pipelines. Essential information for such a study is the amount of asphaltenes that can precipitate and, hence, deposit. In this work, the perturbed chain form of the statistical associating fluid theory (PC-SAFT) is applied to predict the asphaltene precipitation onset condition as well as the amount of precipitate under pressure depletion and high-pressure and high-temperature gas injection conditions. Previous PC-SAFT asphaltene studies in crude oil required the compositional data for both flashed gas and flashed liquid. This... 

    Structural analysis of Y3Ba5Cu8O 19-δ high-Tc superconductor by ab initio density functional theory

    , Article Physica C: Superconductivity and its Applications ; Volume 497 , 15 February , 2014 , 2014, Pages 84-88 ; ISSN: 09214534 Khosroabadi, H ; Rasti, M ; Akhavan, M ; Sharif University of Technology
    Abstract
    The details of the crystal structure of the recently discovered Y 3Ba5Cu8O18+δ (Y358) superconductor have been determined by ab initio density functional theory. Total energy calculation has been performed for three different suggested structures with different oxygen content. The structure with a center of inversion symmetry and the highest oxygen concentration has the lowest total energy. Thus, it is the best choice for the Y358 crystal structure. By investigating the detailed structure, it is seen that this compound is arranged either of YBa2Cu3O7 and YBaCu2O 5 or YBaCu2O5 and BaCuO2 substructural blocks in the c direction. The difference between the total energy of Y358 compound and the... 

    Investigation of membrane preparation condition effect on the PSD and porosity of the membranes using a novel image processing technique

    , Article Journal of Applied Polymer Science ; Volume 131, Issue 4 , 15 February , 2014 ; ISSN: 00218995 Sharak, A. Z ; Samimi, A ; Mousavi, S. A ; Bozarjamhari, R. B ; Sharif University of Technology
    Abstract
    A totally computerized image processing program package is developed to analyze the SEM images of membrane surface and cross-section. Pore size distribution and porosity of the fabricated membranes are determined using the proposed image processing procedure. Furthermore, effect of coagulation bath temperature on the morphology and mechanical properties (such as tensile strength, strain break, tensile energy absorbent, and tensile stiffness) of Polysulfone (PSf) membranes are investigated. The results reveal that the mechanical properties are higher when N-methyl-2-pyrrolidone (NMP) is used as solvent. Also, an increase in the coagulation bath temperature caused a monotonous increase in the... 

    Influence of tool geometry and contact condition on friction stir welding of Al-Cu laminated composites

    , Article Advanced Materials Research ; Vol. 856 , 2014 , pp. 16-21 ; ISSN: 10226680 Beygi, R ; Kazeminezhad, M ; Kokabi, A. H ; Alvani, S. M. J ; Verdera, D ; Loureiro, A ; Sharif University of Technology
    Abstract
    In this study friction stir welding of Al-Cu laminated composites were carried out by two different tool geometries. Welding procedure was carried out from both sides of Al and Cu. Analyzing cross section of welds showed that different contact conditions between shoulder and material, offers different material flow behavior which is dependent on the tool geometry. SEM analyses showed that mixing of materials in nugget region is more pronounced in the advancing side. Also XRD results indicated that welding from Cu side, leads to intermetallic formation in mixed regions  

    3D-1D simulation of flow in fontan operation: effects of antegrade flow on flow pulsations

    , Article Scientia Iranica ; Vol. 21, issue. 4 , 2014 , pp. 1378-1389 ; ISSN: 10263098 Monjezi, M ; Ghoreyshi, S. M ; Saidi, M. S ; Navabi, M. A ; Firoozabad, B. D ; Sharif University of Technology
    Abstract
    This study considers blood flow in total cavopulmonary connection (TCPC) morphology created in Fontan surgical procedure in patients with a single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility since the right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea of increasing pulmonary flow pulsations by keeping Main Pulmonary Artery (MPA) partially open while it was closed in ordinary TCPC operation. The purpose of the present study is to verify the effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary flow pulsations. The 3D geometry is reconstructed from CT... 

    Minimization of target registration error for vertebra in image-guided spine surgery

    , Article International Journal of Computer Assisted Radiology and Surgery ; Vol. 9, issue. 1 , January , 2014 , p. 29-38 Ershad, M ; Ahmadian, A ; Dadashi Serej, N ; Saberi, H ; Amini Khoiy, K ; Sharif University of Technology
    Abstract
    Purpose: The accuracy of pedicle screw placement during image-guided spine surgery (IGSS) can be characterized by estimating the target registration error (TRE). The major factors that influence TRE were identified, minimized, and verified with in vitro experiments. Materials and methods: Computed-tomography- compatible markers are placed over anatomical landmarks of lumbar vertebral segments in locations that are feasible and routinely used in surgical procedures. TRE was determined directly for markers placed on the pedicles of vertebra segments. First, optimum selections of landmarks are proposed for different landmarks according to the minimum achievable TRE values in different... 

    Sparse representation-based super-resolution for diffusion weighted images

    , Article 21st Iranian Conference on Biomedical Engineering, ICBME ; 26-28 November , 2014 , pp. 12-16 ; ISBN: 9781479974177 Afzali, M ; Fatemizadeh, E ; Soltanian-Zadeh, H ; Sharif University of Technology
    Abstract
    Diffusion weighted imaging (DWI) is a non-invasive method for investigating the brain white matter structure. It can be used to evaluate fiber bundles in the brain. However, clinical acquisitions are often low resolution. This paper proposes a method for improving the resolution using sparse representation. In this method a non-diffusion weighted image (bO) is utilized to learn the patches and then diffusion weighted images are reconstructed based on the trained dictionary. Our method is compared with bilinear, nearest neighbor and bicubic interpolation methods. The proposed method shows improvement in terms of Peak Signal-to-Noise Ratio (PSNR) and Structural SIMilarity (SSIM)  

    Wide-band high-efficiency Ku-band power amplifier

    , Article IET Circuits, Devices and Systems ; Vol. 8, issue. 6 , December , 2014 , p. 583-592 ; 1751858X Yousefi, A ; Medi, A ; Sharif University of Technology
    Abstract
    A 37 dBm power amplifier (PA) is designed on a 0.25 μm optical T-gate pseudomorphic high electron mobility transistor (pHEMT) technology. The design of this two-stage PA along with a step-by-step design procedure is presented in this paper. This methodology can be used for design of PA in different technologies and frequencies. The PA delivers 5 W output power over the frequency band of 13-19 GHz. It shows average power-added efficiency of 37% and large signal gain of 15 dB in measurements which is consistent with simulation results. The output power and efficiency of the realised amplifier reach maximums of 37.6 dBm and 45%, respectively. Considering output power, bandwidth, chip area and... 

    Real-time hybrid switching control of automotive cold start hydrocarbon emission

    , Article Journal of Dynamic Systems, Measurement and Control, Transactions of the ASME ; Vol. 136, issue. 4 , January , 2014 Salehi, R ; Shahbakhti, M ; Hedrick, J. K ; Sharif University of Technology
    Abstract
    Reduction of cold start hydrocarbon (HC) emissions requires a proper compromise between low engine-out HC emission and fast light-off of the three way catalytic converter (TWC). In this paper, a hybrid switching system is designed and optimized for reducing HC emissions of a mid-sized passenger car during the cold start phase of FTP-75 (Federal Test Procedure). This hybrid system has the benefit of increasing TWC temperature during the early stages of the driving cycle by switching between different operational modes. The switching times are optimized to reduce the cumulative tailpipe HC of an experimentally validated automotive emission model. The designed hybrid system is tested in... 

    Theoretical-experimental investigation of Co emission from an oil refinery incinerator

    , Article American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM ; Vol. 1C, issue , 2014 Darbandi, M ; Abrar, B ; Yazdi, M. K ; Zeinali, M ; Schneider, G. E ; Sharif University of Technology
    Abstract
    In this paper, we investigate the CO emission from an oil refinery gas incinerator both theoretically and experimentally. At the beginning of this research, our collected data from this incinerator showed that the CO contamination would be far exceeding the permissible environmental standards at the stack exhaust. Therefore, we decided to perform a combined theoretical-experimental study to find a reasonable solution to reduce the CO pollution suitably. Our theoretical study showed that a reliable solution would be to increase the incinerator operating temperature. However, we needed to collect some data from this incinerator to examine if our achieved analytical solution would work...