Sharif Digital Repository

The daily increase of fuel prices, decrease of fuel resources and the need for controlling environmental pollution, reflect the importance of optimizing the heat recovery in different industries. In the past 20 years, Pinch technology has been considered as a powerful tool used for, recovering wasted energies, optimizing the energy transfer between hot and cold streams and reducing the need for additional services. In this thesis, Pinch technology is used to optimize the process of wafer and chocolate production in one of the KitKat’s factories and different retrofits for the increase of the heat recovery are proposed. urthermore, the data collected at this factory is used to investigate the... 

One of the most important concerns in food industry is decreasing the contamination of food and increasing their shelf life. Antimicrobial/antioxidant packaging, an active packaging concept, can be considered an extremely challenging technology that could have a significant impact on shelf-life extension and food safety of meat and meat products. Due to harmfulness of chemical preservatives, their use has been limited and therefore natural antimicrobial/antioxidant agents have become more popular. Propolis is a natural resinous substance, with a high polyphenol content, produced by honeybees and characterized by antimicrobial, anti-inflammatory and antioxidant properties, which make it... 

Enzyme immobilization/drying operations are among the important operations of many biotechnological industrial units. The enzyme used in this study is bacterial alpha-amylase, which is widely used in various industries, including detergents. The production of alpha-amylase enzyme contains a large percentage of water in its composition; therefore, a wet wall tower was designed to conduct the experiments to evaporate the water present in the enzyme liquor, analyze its effects on activity, and also to validate the device. The results showed that in a flow of air around 240m3/hr and ambient temperature of 20◦C, enzyme liquor has a 250% increase in biological activity, which indicates the... 

In this research, we have studied optimization of culture medium and process factors for high alkaline protease production from Bacillus subtilis ATCC 6633 for detergent usage. Five parameter soy bean meal, initial pH, agitation rate, MgSO4, CaCl2 were selected for more studies. At first, one-factor-at-a-time method was applied to investigate effect of each factor separately. Then, optimum condition for maximum protease production was achieved using Minitab software Box-benhnken procedure. According to results, high protease production was seen in soy bean meal, 35 (g/L); MgSO4, 1 (g/L); CaCl2 , 1.5 (g/L); initial pH, 7; agitation rate, 150; inoculum ratio, 12% (v/v). The activity of the... 

The phenomenon of oil drop detachment from solid surface has great importance in many different industries, such as coating, print, membrane emulsification, detergency, and oil enhancement recovery. In our study, we tried to explore this phenomenon. Therefore, we attempted to employ Young equation as force balance for the discussed system which is comprised of n-Decane as oil droplet, aqueous solution (brine) with SDS (Sodium Dodecyl Sulfate), and glass. Also, in order to find governing factors regarding oil detachment process -such as interfacial tension, contact angle, and line friction coefficient- we used an advanced apparatus equipped with horizontal microscope and digital video camera.... 

Biosorption capacity of zinc (II) by biomasses produced from four species of microorganism including two kinds of bacteria (Pseudomonas putida and Streptomyces rimosus) and two kinds of fungi ( Aspergillus niger and Phanerochate chrysosporium) in batch case were investigated and compared. In all cases dried original bio mass and dried pretreated bio mass with NaOH were used. In all cases biosorption capacity of pretreated biomasses were much higher than non-treated biuomasses to the ratio of 3.8 – 1.4 times. Freundlich and Langmuir equilibrium isotherms were used to match with experimental results of this research. Except S.rimosus, all others were completely matched with Langmuir... 

This project related to gas purification according to difference in the deposition point in the fludized bed.The reason for choosing fluidized bed is increasing erosion on wall of bed & increasing on heat transfer compared to other heat exchangers.Separation process, by cooling the wall causes the self- deposition gas phase shifts to solid phase. Solid formed on the wall, act as an insulating layer and greatly reduces the heat transfer therefore part of vessel not used. To solve this problem, the fluidized bed system is offered because the fluid particles can remove the insulating layer beside improving convection heat transfer coefficient. In this work we studied the quantative of erosion... 

In this research, the optimization of culture medium and process conditions for the production of alkaline protease enzyme from Bacillus subtilis ATCC6633 strain for use in the detergent industry has been discussed. Among all the conditions affecting the growth and production of enzymes, the stirrer cycle in the fermenter, which causes different shear rates and is one of the most important factors in the amount of mixing and aeration, was chosen for further study. At first, the results obtained from the incubator shaker were carefully examined, and then different checks were made to adjust the fermenter stirrer speed through diagrams in three flow states: 1-laminar, 2-transitional, and... 

Many aroma compounds of fruit juice recovered by thermal processes like evaporation and distillation can lead to undesirable chemical changes and even their loss. Pervaporation is a promising process for the recovery of volatile organic compounds from their aqueous solutions. In the present work, pervaporation recovery of Butyl acetate as a model solution ofgrape juice aroma compoundwas evaluated with polyethersulfone (PES) and ethylvinylacetate (EVA) membranes. PES membrane generally showed better selectivity so that the separation factor at the concentration of 500 ppmand the temperature of 30°C for PES and EVA membranes, respectively, was 230.78 and 156.9. The effect of two operating... 

Propolis is a resin compound which is collected from different Plant sources by bees. It is processed by salivary enzymes and is combined with wax bee and is used in hives, Specially in entrance door. In this study Propolis is selected as a natural substance. The aim of this study is to change the substance to get use of in industry. For this, first, antimicrobial properties of it was proved and then for industrial use encapsulation was done to keep the capability of it. Since propolis extract was prepared with 70% ethanol, and the encapsulation was done with the polymer-effective material ratio of 5,0,1,2 by a proper polymer with no bad effect on the body. Later an appropriate powder was... 

in the present situation most of the bioproducts are supplied at the global markets. hence newcomers and also existing suppliers should study the economic and social trends to make strategic decisions in order to enter new markets. analysis of the effect of different parameters on the market entrance strategy is the main focus of this thesis. the pivotal subject of this thesis is the analysis of Enzyme industry value chain in Iran and the role of each actor and their interactions with each other. after visualizing the Enzyme industry value chain, we want to answer this question: what are the main obstacles for entering the Enzyme industry due to the interactions between the industry... 

Alpha amylase enzyme is one of the most important enzymes used in a wide range of industries. The enzyme is used in industries such as detergents, food, pharmaceuticals, paper making and textile. Various national and international articles have been published on this enzyme that focused on specific targets. Despite the extensive studies carried out in this area inside the country, there is still no industrial production of alpha amylase and other enzymes in our country. In the view of the fundamental problem of the lack of industrialization of these studies, in addition to the lack of a riskier investor, it seems that there is a lack of industrial vision in these studies.In this study, the... 

Enzymes are an important part of detergents, they reduce the activation energy of the reaction and thus increase the efficiency of the process. Protease enzyme is one of the most common enzymes in detergents. Bacillus strain is the most important strain in the production of this enzyme and among the species of Bacillus, Bacillus subtilis is the most used. Bacillus subtilis is a gram-positive, rod-shaped bacterium. This bacterium is considered a non-pathogenic cell that has the ability to form spores and prevent death and damage in harsh conditions. In this study, CRISPR system was used to modify the genome of Bacillus subtilis ATCC 6633 in order to increase alkaline protease. To increase the... 

Liver metastasis is the leading cause of death in patients with colorectal cancer (CRC). An increasing number of studies have shown that mRNAs, miRNAs, can play an important role in various biological processes that are related to cancer. Identifying and determining the relationship between them can help to diagnose and treat cancer.The aim of this study is to identify miRNA and molecular mRNA markers in the stage of polyp formation in order to diagnose colorectal cancer early and also to introduce therapeutic targets in the stage of metastasis.In this study, two microarray data sets GPL15207 and GPL16384 were analyzed to identify different miRNAs and mRNAs from the GEO database in three... 

Energy and environmental crises force different countries to consider new clean sources of energy, especially renewable energies. Fortunately, Iran is located on the solar belt and has a great potential to utilize this huge source of clean, sustainable, accessible and cheap energy. One of the applications of the solar energy is desalination of salty and polluted waters. In this regard, the performance of Multiple Active Solar Stills is investigated in this research. To do so, four similar samples of this device with one, two, three and four stages, were constructed on which many experiments were conducted for 24 hours periods. Experiments were conducted in both continuous (several days) and... 

In this research, after examining the different strains available in the enzyme center's cell bank, the bacterial strain Pseudomonas aeruginosa (RPMC-B-3556) obtained from the Russian microbial collection was used for lipase production. This microbial strain has the ability to produce extracellular lipase enzyme and for this reason it has been selected as the target strain. The purpose of this research was to optimize the lipase production process in the culture of the appropriate strain. For this purpose, the compounds used in the culture medium are changed to investigate their effect on lipase enzyme activity. Considering that the studied strain has the ability to produce protease enzyme... 

This report models the electricity supply network by means of the ESM software. In this model, the distribution company obtains its final users’ electricity demand from three sources: distributed generation plants owned by private sector, distributed generation plants owned by the distribution company and buying from electricity market (Over distribution network). According to the model, the optimum point of operating the network is a point with maximum profit, minimum waste and environmental effects. The optimum point of supply minimizes the network wastes to an optimum extent. In this model, the distribution company can supply the extra electricity to the electricity market, provided that... 

To investigate the role of biological processes in bacterial transport through poroud media, six rod shaped and motile bacteria were isolated from a crude oil sample. A multi stage screening procedure was utilized to select the most appropriate isolate in microbial enhanced oil recovery applications (MEOR). It was identified and registered as Bacillus licheniformis MS3 in GenBank database. After that, the physical properties and chemical structure of its biosurfactant were determined and it was proved to be a new lipopeptide biosurfactant which was called licheniformin. Power law logistic model was utilized to investigate the kinetics growth of the MS3 strain on insoluble carbon sources ...