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Lithography-directed Self-assembly for Designing Drug Particles of Various Sizes and Morphologies
, M.Sc. Thesis Sharif University of Technology ; Safari, Hanieh (Supervisor)
Abstract
To design a drug delivery system, the drug must be encapsulated within a carrier matrix. One of the main challenges in this field is encapsulating high drug doses while achieving a linear release profile at the target site to maintain drug concentration for optimal therapeutic effects. Consequently, many research groups have focused on refining fabrication techniques to maximize loading efficiency and optimize drug release profiles from delivery systems. A potential approach to addressing this issue is the direct fabrication of a controlled-release system from the active pharmaceutical ingredient (API) itself, eliminating the need for a carrier matrix. Studies have demonstrated that such...
Impact of the Shape of the Loaded Particles on the Mechanical Properties of the Scaffolds and their Interaction with Macrophages
, M.Sc. Thesis Sharif University of Technology ; Mashayekhan, Shohreh (Supervisor) ; Safari, Hanieh (Supervisor)
Abstract
Osteoarthritis is a common musculoskeletal disorder and the most prevalent form of arthritis. To date, no comprehensive cure has been reported for osteoarthritis, and its clinical management remains challenging. The primary therapeutic goals in the early stages of osteoarthritis are to increase joint mobility and control disease progression by continuously releasing drugs and molecules modulating inflammatory responses and reducing pain. Smart drug delivery platforms are one of the strategies to overcome the challenges of injectable and oral medications. Additionally, drug carrier particles can have different therapeutic targets based on their size and shape. Different therapeutic...
Design of pid controller for control of speed of the robotic fish modeled by Lighthill's large amplitude elongated body theory in linear path
, Article ASME International Mechanical Engineering Congress and Exposition, Proceedings, 13 November 2009 through 19 November 2009, Lake Buena Vista, FL ; Volume 10, Issue PART A , 2010 , Pages 117-124 ; 9780791843833 (ISBN) ; Meghdari, A ; Sharif University of Technology
American Society of Mechanical Engineers (ASME)
2010
Abstract
Design of robotic fish based on hydrodynamics is presented and Lighthill's Large Amplitude Elongated Body Theory (LAEBT) is used for modeling of the robotic fish in linear path. A PID controller for control of speed in linear path is designed and simulations are presented which shows its effectiveness for speed control of the robotic fish. It has been shown that in perspective of used approximate LAEBT model, the used control law maintains kinematic parameters and therefore, the associated efficiency will be maintained
On the design of robotic fish based on lighthill's small-amplitude elongated body theory
, Article 2008 ASME International Mechanical Engineering Congress and Exposition, IMECE 2008, Boston, MA, 31 October 2008 through 6 November 2008 ; Volume 11 , 2009 , Pages 119-125 ; 9780791848722 (ISBN) ; Meghdari, A ; Sharif University of Technology
2009
Abstract
This paper addresses the issues of energy efficiency in robotic fish design by use of hydrodynamic models. The use of LighthilPs small-amplitude elongated body theory for designing of robotic fish, obtaining optimal kinematics and dynamic analysis with emphasis on compliant mechanism is presented. Simulation results for a sample case have demonstrated the importance of proposed approach in robotic fish design. Copyright © 2008 by ASME
Research to Provide Iranian Customer Satisfaction Index Model in Industry, Case Study: Iran Khodro Co., Golrang Co. and Kaleh Co
, M.Sc. Thesis Sharif University of Technology ; Mostafavi, Mostafa (Supervisor)
Abstract
In recent decades many countries have attempted to measure and formulate customer satisfaction index (CSI), as an important factor in micro and macro-economic level. In developed country CSI has the same value of GNP. Customer Satisfaction Index model actually represents the relationship between primary factors of satisfaction and satisfaction results in the macro level for a country and includes all business aspects. In many countries, industrial companies have a wide range of products and providing Customer Satisfaction Index model for this aspect which can be a base of presenting national customer satisfaction index model. Accordingly, the main goal of this study is providing an Iranian...
Investigating the Electrochemical Behavior of Co-Zn Sulfides and Hydroxides on Copper Oxide Nano-structures Grown on Copper Foam for Application in Electrochemical Supercapacitors
, M.Sc. Thesis Sharif University of Technology ; Shahrokhian, Saeed (Supervisor)
Abstract
In the first part, Co-Zn hydroxides were deposited onto CuO nanorods, and their electrochemical behavior and capacitive performance were investigated. To this end, Cu(OH)2 nanorods were grown on copper foam through a chemical process. Then, Cu(OH)2 were converted to CuO nanorods via a calcination process. In the next step, Co-Zn-OH sheets were electrodeposited on CuO nanorods. FE-SEM images of the prepared electrodes demonstrate the formation of Co-Zn-OH nanosheets onto CuO nanorods. Crucial electrochemical evaluations such as cyclic voltammetry (CV), galvanostatic charge/discharge (GCD), rate capability, and electrochemical impedance spectroscopy (EIS) were carried out. According to the...
Fidelity-based supervised and unsupervised learning for binary classification of quantum states
, Article European Physical Journal Plus ; Volume 136, Issue 3 , 2021 ; 21905444 (ISSN) ; Rezakhani, A. T ; Sharif University of Technology
Springer Science and Business Media Deutschland GmbH
2021
Abstract
Here, we develop two quantum-computational schemes for supervised and unsupervised classification tasks in a quantum world by employing the quantum information-geometric tools of quantum fidelity and quantum search algorithm. Presuming that pure states of a set of given quantum systems (or objects) belong to one of two known classes, the objective here is to decide to which of these classes each system belongs—without knowing its state. The supervised binary classification algorithm is based on having a training sample of quantum systems whose class memberships are already known. The unsupervised binary classification algorithm, however, uses a quantum oracle which knows the class membership...
Paving property for real stable polynomials and strongly rayleigh processes
, Article Bernoulli ; Volume 28, Issue 2 , 2022 , Pages 1198-1223 ; 13507265 (ISSN) ; Barzegar, M ; Sharif University of Technology
Bernoulli Society for Mathematical Statistics and Probability
2022
Abstract
One of the equivalent formulations of the Kadison–Singer problem which was resolved in 2013 by Marcus, Spielman and Srivastava, is the “paving conjecture”. In this paper, we first extend this result to real stable polynomials. We prove that for every multi-affine real stable polynomial satisfying a simple condition, it is possible to partition its set of variables to a small number of subsets such that the “restriction” of the polynomial to each subset has small roots. Then, we derive a probabilistic interpretation of this result. We show that there exists a partition of the underlying space of every strongly Rayleigh process into a small number of sets such that the restriction of the point...
Hybrid supercapacitors constructed from double-shelled cobalt-zinc sulfide/copper oxide nanoarrays and ferrous sulfide/graphene oxide nanostructures
, Article Journal of Colloid and Interface Science ; 2020 ; Hekmat, F ; Shahrokhian, S ; Sharif University of Technology
Academic Press Inc
2020
Abstract
Evolution of renewable energies in the era of the modernized world has been strongly tied up to the incessant development of high-performance energy storage systems benefiting from both high energy and power densities. In the present work, binder-free positive electrodes are fabricated via a facile electrochemical deposition route in which copper oxide nanorods (CuO NRs) directly grown onto the copper foam (CF) are decorated with bimetallic cobalt-zinc sulfide nanoarrays (Co-Zn-S NAs). The fabricated Co-Zn-S@CuO-CFs represent promising specific capacity of 317.03 C.g−1 at 1.76 A.g−1, along with superior cyclic stability (113% retention after 4500 cycles). Negative electrodes were further...
Hybrid supercapacitors constructed from double-shelled cobalt-zinc sulfide/copper oxide nanoarrays and ferrous sulfide/graphene oxide nanostructures
, Article Journal of Colloid and Interface Science ; Volume 585 , 2021 , Pages 750-763 ; 00219797 (ISSN) ; Hekmat, F ; Shahrokhian, S ; Sharif University of Technology
Academic Press Inc
2021
Abstract
Evolution of renewable energies in the era of the modernized world has been strongly tied up to the incessant development of high-performance energy storage systems benefiting from both high energy and power densities. In the present work, binder-free positive electrodes are fabricated via a facile electrochemical deposition route in which copper oxide nanorods (CuO NRs) directly grown onto the copper foam (CF) are decorated with bimetallic cobalt-zinc sulfide nanoarrays (Co-Zn-S NAs). The fabricated Co-Zn-S@CuO-CFs represent promising specific capacity of 317.03 C.g−1 at 1.76 A.g−1, along with superior cyclic stability (113% retention after 4500 cycles). Negative electrodes were further...
3D flower-like nickel cobalt sulfide directly decorated grassy nickel sulfide and encapsulated iron in carbon sphere hosts as hybrid energy storage device
, Article Applied Surface Science ; Volume 558 , 2021 ; 01694332 (ISSN) ; Hekmat, F ; Shahrokhian, S ; Sharif University of Technology
Elsevier B.V
2021
Abstract
Developing high-performance supercapacitors is of great significance in the area of renewable energies by virtue of having both high energy and power densities. In this work, an innovative strategy is employed for the fabrication of binder-free binary nickel–cobalt-sulfide (NCS) nanosheets (NSs) directly decorated onto the hydrothermal nickel-sulfide (Ni3S2) nanowires (NWs) as the positive electrodes. The NCS/Ni3S2-nickel foam (NF) positive electrodes rendered superior specific capacity of 499.1 mAh.g−1 at 6 A.g−1. Encapsulated iron into the carbon sphere hosts (Fe-HTCSs) are used as the negative counterparts, exhibiting remarkable specific capacitance of 336.6 F.g−1 (at 0.1 A.g−1). The...
Physiochemical evaluation of a ternary magnetic MIL-101(Fe)–GO–Fe3O4 utilized for photocatalytic conversion of CO2 into methanol under ultraviolet light irradiation
, Article Russian Journal of Physical Chemistry A ; Volume 97, Issue 7 , 2023 , Pages 1601-1614 ; 00360244 (ISSN) ; Vafajoo, L ; Kazemeini, M ; Sharif University of Technology
Pleiades Publishing
2023
Abstract
Abstract: In this research, photocatalytic conversion of CO2 to methanol was investigated under ultraviolet (UV-A) light. For this purpose, a number of the metal–organic framework photocatalysts, including MIL-101(Fe), graphene oxide (GO), GO–iron oxide (Fe3O4), MIL-101(Fe)–GO–Fe3O4 5, 10, and 20% were synthesized and characterized by X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy (RAMAN), scanning electron microscope (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy/map (EDS/map), Brunauer–Emmett–Teller (BET) surface area analysis and Barrett–Joyner–Halenda (BJH), UV–Vis diffuse reflectance spectroscopy...
An Extension of Hedberg’s Convolution Inequality and Applications
, M.Sc. Thesis Sharif University of Technology ; Ranjbar Motlagh, Alireza (Supervisor)
Abstract
HAedbbergshtasrpraovecdtthefolowinginequalityforany1pnof;nandpIsuchft(xa)tCkfkpnp(Mf(x)1np .8Tfh2erLepe(xRisnt)saCindependent fHwuhhenedecrSbteioeobrnIgo'losefvinffie.nqieusqautlhiatleyityhReefloipsrsztihpneodtReenaeltiisinazglpwooftitefhntpaiarnlod,bil.Meem.fsrdeelnatoitnegtuhseinHgatrhdeyf-uLnitcttlieowno.ofodrmexaaxmimpalel SwohbeorelevCiniseqinudaeliptyencdaenntbeofexft,racactnkeIdbefrdofmekdnuHnspeepddbferroCgm'ksfHinepedqbuearlgit'ys.iHneeqrueawlietyw.iAllgseontehraeliczleasHsiecda-l berg'sinequalitytoOrliczspaces.
On Brouwer’s Homeomorphisms in Plane
, M.Sc. Thesis Sharif University of Technology ; Fanayi, Hamid Reza (Supervisor)
Abstract
In this project we investigate Brouwer’s homeomorphisms in the plane. A Brouwer’s homeomorphisms is an orientation-preserving and fixed-point-free homeomorphism in the plane. For this purpose we prove Brouwer and scoenflies Theorem in the plane. we prove that bounded connected sets in the Plane that are open or closed and meets an infinite number of it’s iterates under Brouwer homeomorphisms must meets all of them.
Pinch Analysis of Heat Exchanger Networks in the Crude Oil Distillation Unit of Bandar-Abbas Refinery
, M.Sc. Thesis Sharif University of Technology ; Sadrhosseini, Hanieh (Supervisor) ; Shafii, Mohammad Behshad (Supervisor)
Abstract
Since oil prices continue to increase, energy conservation remains the prime industrial concern. Existing processes in power plants and oil refineries are not energy efficient as they should be therefore new projects can be defined to increase the energy efficiency without incurring any cost. The most appropriate utility for the processes should be explored to reduce emissions, increase the plant capacities and improve product qualities and energy efficiencies by one coherent strategic plan for the overall site which can be achieved by a full understanding of pinch technology and awareness of the available tools for applying it in practical way. Since the distillation unit of crude oil...
High resolution DOA estimation in fully coherent environments
, Article Progress In Electromagnetics Research C ; Volume 5 , 2008 , Pages 135-148 ; 19378718 (ISSN) ; Emadi, M ; Sadeghi, K ; Sharif University of Technology
Electromagnetics Academy
2008
Abstract
A novel method for direction-of-arrival (DOA) estimation is proposed. This technique employs the excellent performance of Bartlett method in coherent environments as well as high resolution and low computational complexity of Beamspace MUSIC. Simulation results show that the use of Beamspace MUSIC with Bartlett yields significantly improved performance compared to the original MUSIC especially in highly correlated situations. © 2008, Electromagnetics Academy. All rights reserved
Optimum selection of "number of seats/Cargo volume" for transports in uncertain business environment
, Article Journal of Aircraft ; Volume 45, Issue 1 , 2008 , Pages 98-105 ; 00218669 (ISSN) ; Malaek, S. M. B ; Sharif University of Technology
American Institute of Aeronautics and Astronautics Inc
2008
Abstract
Increasing competition in the transport commercial market has resulted in many changes in the aircraft design process. There is a great tendency to include economic factors such as "affordability" In the design process. On the other hand, the so-called market dynamics are also getting complicated and a design team has to deal with many uncertainties as far as the business environment is concerned. This leads to the need for new decision-making tools in the early stages of the design process. This paper introduces a decision-making algorithm based on fuzzy logic systems which provides a structured approach to deal with uncertainties in the aircraft preliminary design. The developed tool leads...
Effect of Waste Gate Turbocharged Performance Gas Engine Turbo Charger
, M.Sc. Thesis Sharif University of Technology ; Hajilouy Benisi, Ali (Supervisor)
Abstract
The project aims to select the best Waste gate opening pressure for my Turbocharged gas engine is m355G. For this purpose GT-power software for modeling engine power is used. it is reduced to the 38/11 percent. After checking the model in several Waste gate opening pressure Turbocharged Gas engine performance is evaluated and the best Waste gate opening pressure is achieved. The results show that the engine brake specific fuel consumption by changing the opening pressure of 165 mm Hg to 255 mm Hg 4/03 percent and 14/19 percent of the engine power is increased. Also opening pressure of 265 mm Hg to 255 mm Hg engine brake specific fuel consumption 0/25 percent and 0/88 percent of the engine...
Design of Digital Block of Receiver Section of Smart Antenna System
, M.Sc. Thesis Sharif University of Technology ; Haj Sadeghi, Khosro (Supervisor)
Abstract
In recent years with the increase of cellular phone subscribers, demand for high capacity networks is inevitable. For this reason, different methods have been proposed to increase the channel capacity. One method which has become popular in recent years is utilizing of Smart Antenna Systems. Smart antennas basically attempt to enhance the desired signal power and suppress the interferers by beamforming toward the DOA (direction-of-arrival) of the desired signal and nullsteering in the interferences’ DOAs. Smart Antennas first find the direction of signal sources, and then put the main gain toward the desired signal and put the nulls toward unwanted signals. As a result, we can obtain the...
Xylanase production under solid state fermentation by aspergillus niger
, Article International Journal of Engineering, Transactions B: Applications ; Volume 24, Issue 3 , March , 2011 , Pages 197-208 ; 1728-144X (ISSN) ; Alemzadeh, I ; Khanahmadi, M ; Roostaazad, R ; Sharif University of Technology
Materials and Energy Research Center
2011
Abstract
Central composite orthogonal design was applied to quantify relations of xylanase production, loss of dry matter and change of pH with four critical variables during solid state fermentation of a mixture of wheat bran and wheat straw on which Aspergillus niger CCUG 33991 was cultivated. The studied variables included the percentage of wheat straw, wheat bran, temperature, moisture content, and fermentation time. The second-order quadratic model predicted the xylanase activity at a suitable set of conditions namely 29°C, 55% moisture content, and 50 hours of fermentation to be 1465 U/g of fermented dry matter which differed less than 6% from measured value at this set of conditions....