Sharif Digital Repository

It is important to provide an appropriate and economically method with technical and engineering considerations to stabilize excavated underground spaces. The necessity of this, especially for the construction of underground metro stations located in the cities which faces many problems, is more evident. In this research, it has been tried to introduce an optimal method according to the type of area for the construction of the underground station. In order to obtain stress and strain condition in structural elements and surface deformations due to different stages of excavating, numerical modeling in FLAC3D has been used. By examining the parameters that affect the sustainability of this... 

In recent years, monoclonal antibodies have gained attention as highly effective drugs for treating diseases, especially cancer. The high binding affinity between an antibody and its corresponding antigen is one of the key factors in triggering an effective immune response. Modeling binding affinity using machine learning is considered a promising and cost-effective computational approach; however, due to the lack of training data, the performance of these models is often poor and limited. In contrast, recent advances in geometric learning have demonstrated that incorporating the three-dimensional geometry of protein structures in the learning process can significantly impact 3D... 

In the last decades, Reaction Time research has been extended to cognitive science and more specifically human information-processing research and has gained momentum (Shim, 1996). The present study examined the reaction time in processing marked and unmarked structures with regard to the four types of conditionals (considered as unmarked, less marked, marked and strongly markedness, respectively) and prepositions (preposition pied piping that is considered as unmarked and preposition stranding as marked). To this end, two softwares were developed for which the items relating to conditionals were chosen from the Bernet’s test (1985) and the ones pertinent to prepositions were taken from... 

Using Functionally Graded Materials (FGMs) in hot sections of aged aircrafts is one of the most important ways for life extending of Thermal Barrier Coatings (TBCs). Sudden variation of thermal stresses in interface of bond coat and ceramic coat layers could be changed to gradual variation with use of FGMs. The stress in FGMs has been the subject of several researches. Both macro and micromechanical modeling approaches have been used in these studies. In the macro mechanical approach, FGM is modeled as a multi-layer composite in which mechanical properties of each layer is found by averaging the properties and volume fraction of FGM constituents through the thickness of the layer. In this... 

Designing a part of an on site repair system for refurbishing steam turbine high pressure control valve has been done in this project. The main role of this control valve is to control the input flow to the turbine in different working condition . However, due to high temperature and pressure, the seat is exposed to erosion. R epairing this part in workshop requires great amount of time and cost, because the valve is a part of the turbine body and must be cut and rewelded to the turbine body. S o using an on-site repair method is highly needed. In addition, due to the limited visibility and access to the valve seat, and accurate... 

The direct technique in which response of the soil and the structure is obtained using numerical methods like finite element is not an appropriate method for seismic analysis of soil-structure interaction of buildings. For this reason, the effects of the foundation and retaining walls are considered for a building with underground floors. Interaction models include a concrete moment frame with ten stories and zero to five underground floors in which constructed on a specific soil and analyzed in FLAC software. Three types of accelerograph Tabas, El-Centro, and Luma are used for time history analysis. Indeed, for a model with a rigid foundation, a ten stories moment frame without an... 

In this research, a mathematical model was developed to simulate a two-phase fluidized bed reactor for oxidative dehydrogenation of propane to propylene. Since the assumption of minimum fluidization condition for the emulsion phase is not realistic , the hydrodynamic structure proposed by Cui et al. was used in this study. The mass balances in unsteady state was obtained in a control volume. The differential equations contain three terms, corresponding to the mass transfer by convection, the exchange between phases and the reaction. All differential equations based upon material balances, hydrodynamics and kinetics for all components were solved numerically using MATLAB software 2010a.... 

This thesis has been done with the goal of comprehensive neutronic calculation of a small size High Temperature Gas Cooled Reactor and HTTR was selected as a reference reactor for simulations. Calculations are divided into four parts of zero and full power stochastic calculations, deterministic calculations and noise analysis. In zero power calculations, an algorithm is proposed for modeling random arrangement of TRISO particles in the fuel compacts of HTTR. The effect of this arrangement on criticality calculations, i.e. effective multiplication factor and critical position of control rods, is then compared with regular arrangement. In the second part, full power calculations with the use... 

Platelet Rich Plasma (PRP) is a blood-derived product containing concentrate of platelets, which are a rich source of autologous growth factors. PRP injection has been used clinically as a therapeutic method for cartilage repair. However, clinical efficiency of this method is unpredictable, maybe as a result of burst release of growth factors then fail cell-stimulating potential as most biomolecules are cleaned before they can exert a therapeutic effect. The aim of this project was to prepare a suitable scaffold for PRP delivery to regenerate cartilage injuries. In order to resemble polysaccharide-protein nature of the cartilaginous extracellular matrix, in this study, we developed an... 

We present a systematic study of the composition, electronic structure, and the band gap energy in pure, Cu-doped and O-vacancy@Cu-doped TiO2 using periodic density functional theory (DFT) calculations by several techniques implemented by Abinit code. Herein, the effect of Cu impurity and O-vacancy in three famous crystalline structures of TiO2 i.e. rutile, anatase and brookite, with 6.25% and 12.5% of Cu impurity were investigated. Bulk titania was modeled using 2×2×1, 2×1×1 and 1×1×1 super cells (24 atoms with formula of Ti8O16) and 2×2×2, 2 2×1 and 1×2×1 super cells (48 atoms with formula of Ti16O32) for rutile, anatase and brookite phases, respectively. One Ti atom replaces with Cu atom... 

The introduction of Minimally Invasive Surgery (MIS) has deeply influenced modern surgery. Despite all the advantages for the patient, this method produces some limitations for the surgeon. Limitations such as reducing degrees of freedom resulting in the loss of dexterity, depriving surgeons of the depth perception and sense of touch lead to human errors due to fatigue and intense mental activity. Overcoming these limitations is the reason for robots entering the operating rooms. In this research a robot-assisted surgery system including two 5-DOF robots is utilized. The goal of this research is to model and simulate this system and also to design a bilateral controller to provide haptic... 

Statistical studies indicate the fact that in Iran, like many other developing countries, a significant percentage of buildings are made of traditional materials and most of them are adobe buildings especially in rural areas. Furthermore, geological data indicates that Iran is located in alps-Himalayas seismic zone and exposed by destructive earthquakes and adobe buildings suffer the most damages comparing with other type of the structures. According to these explanations, this research deals with adobe buildings behavior and provides solutions for reinforcing them and improving the seismic response of these buildings. These studies include numerical modeling with finite elements methods by... 

In this thesis we consider the problem of distributed computation by many processors.We mainly concentrate on matrix multiplication problem in this thesis because of its importance. A distributed system consists of N worker processors and one master processor. The master processor should distribute the computation between workers and after computation in each of them, collect the results. In this thesis, we are going to mitigate the effect of straggler processors by using coding methods. Straggler processors can cause delays in the computation time.In this thesis, we firstly introduce a method to multiply any number of matrices in each other. The proposed method occurred in one shot without... 

The main goal of current investigation was partial reduction of Fe2O3 available in Hematite-rich ore to Magnetite by Fludization Bed method. The reductive gas, CO, was produced by incomplete combustion of Acetylene and Airmixed in inappropriate ratio. X-Ray Diffraction and X-Ray Florescence analyses were implemented in order to conducting qualitative analysis of present phases before and after reduction of the ore. Quantitative analysis of the same phases was also conducted by Titration. The latter analysis revealed the precise magnitude of available iron in each of the oxide containing phases. The chemical composition of the reactor gas was also determined before and after reduction... 

Abstract The problem of competetive facility location can be defined as follows: There are a number of customers in the form of points in space, and two players arrange a number of facilities in the form of points in space, given some limitations, respectively. Each customer’s connection to each facility has a cost for the customer and an advantage for the facility, and each customer wants to be connected to at most one of the facilities which has the lowest cost for him. The goal is to find the strategy of placing the facilities and determining the cost which the facility receives from the customer, in such a way that the player’s profit is maximised.In this thesis, we first sought to... 

Zero knowledge proofs allow a person (prover) to convince another person (verifier) that he has performed a specific computation on a secret data correctly, and has obtained a true answer, without having to disclose the secret data. QAP (Quadratic Arithmetic Program) based zkSNARKs (zero knowledge Succinct Non-interactive Argument of Knowledge) are a type of zero knowledge proof. They have several properties that make them attractive in practice, e.g. verifier's work is very easy. So they are used in many areas such as Blockchain and cloud computing. But yet prover's work in QAP based zkSNARKs is heavy, therefore, it may not be possible for a prover with limited processing resource to run...