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Investigation of the Effect of High Accelerations on Human Cardiac Function

Jamshidi, Masoud | 2013

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 44240 (08)
  4. University: Sharif University of Technology
  5. Department: Mechanical Engineering
  6. Advisor(s): Ahmadian, Mohammad Taghi; Meghdari, Ali
  7. Abstract:
  8. When the human body is subjected to high accelerations, cardiac function and blood supply to the body can be changed. Due to the complex geometrical and mechanical properties of heart, finite element method is useful way for analysis of response of this structure under different load types. Modeling heart using finite element method requires mechanical and geometrical properties of heart. Soft tissues modeling, such as heart muscle using finite element method is one of the most challenging issues in field of biomechanics. In this thesis, the mechanical properties of heart are obtained by performing experimental compression tests on samples of fresh bovine heart. Using obtained experimental data, different types of hyperelastic material models typically used for soft tissue modeling, were investigated and by comparing curve fitting results, the Yeoh hyperelastic model is selected. For finite element modeling and analysis of cardiac function, three-dimensional model of heart in Mimics and Catia software is constructed using cardiac MRI images. Then the constructed heart model is imported ABAQUS FEM software and calculated hyperelastic material coefficients are implemented to the heart model. Considering appropriate boundary conditions, finite element analysis of heart for different levels of acceleration in the upward direction of vertical axis of body during rapid filling phase of the cardiac cycle is done. Finally finite element results of deformation, stress and strain distribution in heart are investigated. The ventricular volume change caused by the acceleration which is important in the amount blood supply to the body is also calculated
  9. Keywords:
  10. Finite Element Method ; Hyperelastic Materials ; Cardiac Cine Magnetic Resonance Imagin (MRI) ; Heart Soft Tissue ; Acceleration

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